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Results: 1 to 20 of 92

1.

Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.

Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW Jr, Laezza FM, Watson CS, Briggs JM, Cunningham KA.

J Neurosci. 2013 Jan 23;33(4):1615-30. doi: 10.1523/JNEUROSCI.2656-12.2013.

PMID:
23345234
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Intracellular 5-HT 2C-receptor dephosphorylation: a new target for treating drug addiction.

Müller CP, Carey RJ.

Trends Pharmacol Sci. 2006 Sep;27(9):455-8. Epub 2006 Jul 27. Review.

PMID:
16876260
[PubMed - indexed for MEDLINE]
3.

Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex.

Anastasio NC, Lanfranco MF, Bubar MJ, Seitz PK, Stutz SJ, McGinnis AG, Watson CS, Cunningham KA.

J Neurochem. 2010 Jun;113(6):1504-15. doi: 10.1111/j.1471-4159.2010.06694.x. Epub 2010 Mar 24.

PMID:
20345755
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse.

Ji SP, Zhang Y, Van Cleemput J, Jiang W, Liao M, Li L, Wan Q, Backstrom JR, Zhang X.

Nat Med. 2006 Mar;12(3):324-9. Epub 2006 Feb 12.

PMID:
16474401
[PubMed - indexed for MEDLINE]
5.

The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins.

Bécamel C, Gavarini S, Chanrion B, Alonso G, Galéotti N, Dumuis A, Bockaert J, Marin P.

J Biol Chem. 2004 May 7;279(19):20257-66. Epub 2004 Feb 26.

PMID:
14988405
[PubMed - indexed for MEDLINE]
Free Article
6.

PTEN-5-HT2C coupling: a new target for treating drug addiction.

Maillet JC, Zhang Y, Li X, Zhang X.

Prog Brain Res. 2008;172:407-20. doi: 10.1016/S0079-6123(08)00920-5. Review.

PMID:
18772044
[PubMed - indexed for MEDLINE]
7.
8.

Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A/2C agonism.

Bishop C, Tessmer JL, Ullrich T, Rice KC, Walker PD.

J Pharmacol Exp Ther. 2004 Aug;310(2):687-94. Epub 2004 Mar 25.

PMID:
15044557
[PubMed - indexed for MEDLINE]
Free Article
9.

Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors.

Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S, Heisler LK.

Endocrinology. 2008 Mar;149(3):1323-8. Epub 2007 Nov 26.

PMID:
18039773
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Identification of the binding sites and selectivity of sarpogrelate, a novel 5-HT2 antagonist, to human 5-HT2A, 5-HT2B and 5-HT2C receptor subtypes by molecular modeling.

Rashid M, Manivet P, Nishio H, Pratuangdejkul J, Rajab M, Ishiguro M, Launay JM, Nagatomo T.

Life Sci. 2003 May 30;73(2):193-207.

PMID:
12738034
[PubMed - indexed for MEDLINE]
11.

Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.

Labasque M, Reiter E, Becamel C, Bockaert J, Marin P.

Mol Biol Cell. 2008 Nov;19(11):4640-50. doi: 10.1091/mbc.E08-04-0422. Epub 2008 Sep 3.

PMID:
18768750
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hypothalamic Ahi1 mediates feeding behavior through interaction with 5-HT2C receptor.

Wang H, Huang Z, Huang L, Niu S, Rao X, Xu J, Kong H, Yang J, Yang C, Wu D, Li S, Li XJ, Liu T, Sheng G.

J Biol Chem. 2012 Jan 13;287(3):2237-46. doi: 10.1074/jbc.M111.277871. Epub 2011 Nov 28.

PMID:
22123816
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.

Moya PR, Berg KA, Gutiérrez-Hernandez MA, Sáez-Briones P, Reyes-Parada M, Cassels BK, Clarke WP.

J Pharmacol Exp Ther. 2007 Jun;321(3):1054-61. Epub 2007 Mar 2.

PMID:
17337633
[PubMed - indexed for MEDLINE]
Free Article
14.

Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist.

Dunlop J, Watts SW, Barrett JE, Coupet J, Harrison B, Mazandarani H, Nawoschik S, Pangalos MN, Ramamoorthy S, Schechter L, Smith D, Stack G, Zhang J, Zhang G, Rosenzweig-Lipson S.

J Pharmacol Exp Ther. 2011 Jun;337(3):673-80. doi: 10.1124/jpet.111.179572. Epub 2011 Mar 14.

PMID:
21402690
[PubMed - indexed for MEDLINE]
Free Article
15.

Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization.

Thomsen WJ, Grottick AJ, Menzaghi F, Reyes-Saldana H, Espitia S, Yuskin D, Whelan K, Martin M, Morgan M, Chen W, Al-Shamma H, Smith B, Chalmers D, Behan D.

J Pharmacol Exp Ther. 2008 May;325(2):577-87. doi: 10.1124/jpet.107.133348. Epub 2008 Feb 5.

PMID:
18252809
[PubMed - indexed for MEDLINE]
Free Article
16.

Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone.

Harada K, Aota M, Inoue T, Matsuda R, Mihara T, Yamaji T, Ishibashi K, Matsuoka N.

Eur J Pharmacol. 2006 Dec 28;553(1-3):171-84. Epub 2006 Sep 28.

PMID:
17074317
[PubMed - indexed for MEDLINE]
17.

Regulation of serotonin-2C receptor G-protein coupling by RNA editing.

Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, Emeson RB.

Nature. 1997 May 15;387(6630):303-8.

PMID:
9153397
[PubMed - indexed for MEDLINE]
18.

Differential regulation of the mesoaccumbens circuit by serotonin 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.

McMahon LR, Filip M, Cunningham KA.

J Neurosci. 2001 Oct 1;21(19):7781-7.

PMID:
11567068
[PubMed - indexed for MEDLINE]
Free Article
19.

Prospects for serotonin 5-HT2R pharmacotherapy in psychostimulant abuse.

Bubar MJ, Cunningham KA.

Prog Brain Res. 2008;172:319-46. doi: 10.1016/S0079-6123(08)00916-3. Review.

PMID:
18772040
[PubMed - indexed for MEDLINE]
20.

Oligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramers.

Herrick-Davis K, Grinde E, Lindsley T, Cowan A, Mazurkiewicz JE.

J Biol Chem. 2012 Jul 6;287(28):23604-14. doi: 10.1074/jbc.M112.350249. Epub 2012 May 16.

PMID:
22593582
[PubMed - indexed for MEDLINE]
Free PMC Article

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