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Results: 1 to 20 of 150

1.

[Therapy resistant diabetes mellitus and lipodystrophy: leptin therapy leads to improvement].

Jazet IM, Jonker JT, Wijngaarden MA, Lamb H, Smelt AH.

Ned Tijdschr Geneeskd. 2013;157(4):A5482. Review. Dutch.

PMID:
23343738
[PubMed - indexed for MEDLINE]
2.

Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy.

Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Gorden P, Shulman GI.

J Clin Invest. 2002 May;109(10):1345-50.

PMID:
12021250
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Leptin-replacement therapy for lipodystrophy.

Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A.

N Engl J Med. 2002 Feb 21;346(8):570-8.

PMID:
11856796
[PubMed - indexed for MEDLINE]
Free Article
4.

Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.

Park JY, Chong AY, Cochran EK, Kleiner DE, Haller MJ, Schatz DA, Gorden P.

J Clin Endocrinol Metab. 2008 Jan;93(1):26-31. Epub 2007 Oct 16.

PMID:
17940115
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Metabolic correction induced by leptin replacement treatment in young children with Berardinelli-Seip congenital lipoatrophy.

Beltrand J, Beregszaszi M, Chevenne D, Sebag G, De Kerdanet M, Huet F, Polak M, Tubiana-Rufi N, Lacombe D, De Paoli AM, Levy-Marchal C.

Pediatrics. 2007 Aug;120(2):e291-6.

PMID:
17671040
[PubMed - indexed for MEDLINE]
Free Article
6.

Long-term efficacy of leptin replacement in patients with generalized lipodystrophy.

Javor ED, Cochran EK, Musso C, Young JR, Depaoli AM, Gorden P.

Diabetes. 2005 Jul;54(7):1994-2002.

PMID:
15983199
[PubMed - indexed for MEDLINE]
Free Article
7.

Clinical features and metabolic derangements in acquired generalized lipodystrophy: case reports and review of the literature.

Misra A, Garg A.

Medicine (Baltimore). 2003 Mar;82(2):129-46. Review.

PMID:
12640189
[PubMed - indexed for MEDLINE]
8.

[Difficult to manage diabetes mellitus associated with generalized congenital lipodystrophy. Report of two cases].

Cardona-Hernández R, Suárez-Ortega L, Torres M.

An Pediatr (Barc). 2011 Feb;74(2):126-30. doi: 10.1016/j.anpedi.2010.09.020. Epub 2010 Dec 17. Spanish.

PMID:
21168376
[PubMed - indexed for MEDLINE]
Free Article
9.

Clinical effects of long-term metreleptin treatment in patients with lipodystrophy.

Chan JL, Lutz K, Cochran E, Huang W, Peters Y, Weyer C, Gorden P.

Endocr Pract. 2011 Nov-Dec;17(6):922-32. doi: 10.4158/EP11229.OR.

PMID:
22068254
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.

Ebihara K, Kusakabe T, Hirata M, Masuzaki H, Miyanaga F, Kobayashi N, Tanaka T, Chusho H, Miyazawa T, Hayashi T, Hosoda K, Ogawa Y, DePaoli AM, Fukushima M, Nakao K.

J Clin Endocrinol Metab. 2007 Feb;92(2):532-41. Epub 2006 Nov 21.

PMID:
17118991
[PubMed - indexed for MEDLINE]
11.

The clinical efficacy of the adipocyte-derived hormone leptin in metabolic dysfunction.

Gorden P, Park JY.

Arch Physiol Biochem. 2006 Apr;112(2):114-8. Review.

PMID:
16931453
[PubMed - indexed for MEDLINE]
12.

Insulin resistance, acanthosis nigricans, and hypertriglyceridemia.

Eberting CL, Javor E, Gorden P, Turner ML, Cowen EW.

J Am Acad Dermatol. 2005 Feb;52(2):341-4. No abstract available.

PMID:
15692481
[PubMed - indexed for MEDLINE]
13.

Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy.

Javor ED, Ghany MG, Cochran EK, Oral EA, DePaoli AM, Premkumar A, Kleiner DE, Gorden P.

Hepatology. 2005 Apr;41(4):753-60.

PMID:
15791619
[PubMed - indexed for MEDLINE]
14.

Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy.

Simha V, Szczepaniak LS, Wagner AJ, DePaoli AM, Garg A.

Diabetes Care. 2003 Jan;26(1):30-5.

PMID:
12502655
[PubMed - indexed for MEDLINE]
15.

The liver diseases of lipodystrophy: the long-term effect of leptin treatment.

Safar Zadeh E, Lungu AO, Cochran EK, Brown RJ, Ghany MG, Heller T, Kleiner DE, Gorden P.

J Hepatol. 2013 Jul;59(1):131-7. doi: 10.1016/j.jhep.2013.02.007. Epub 2013 Feb 21.

PMID:
23439261
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Triglyceride-induced diabetes mellitus in congenital generalized lipodystrophy.

Montenegro RM Jr, Montenegro AP, Fernandes MI, de Moraes RR, Elias J Jr, Gouveia LM, Muglia VF, Foss MC, Moreira AC, Martinelli CE Jr.

J Pediatr Endocrinol Metab. 2002 Apr;15(4):441-7.

PMID:
12008692
[PubMed - indexed for MEDLINE]
17.

[Genetic and metabolic description of five patients with Berardinelli-Seip syndrome].

Barra CB, Savoldelli RD, Manna TD, Kim CA, Magre J, Porta G, Setian N, Damiani D.

Arq Bras Endocrinol Metabol. 2011 Feb;55(1):54-9. Portuguese.

PMID:
21468520
[PubMed - indexed for MEDLINE]
Free Article
18.

[Lipodystrophy. Mechanisms, clinical presentation, therapy].

Miehle K, Stumvoll M, Fasshauer M.

Internist (Berl). 2011 Apr;52(4):362, 364-6, 368-70 passim. doi: 10.1007/s00108-010-2711-5. German.

PMID:
21424143
[PubMed - indexed for MEDLINE]
19.

Leptin activates hepatic 5'-AMP-activated protein kinase through sympathetic nervous system and α1-adrenergic receptor: a potential mechanism for improvement of fatty liver in lipodystrophy by leptin.

Miyamoto L, Ebihara K, Kusakabe T, Aotani D, Yamamoto-Kataoka S, Sakai T, Aizawa-Abe M, Yamamoto Y, Fujikura J, Hayashi T, Hosoda K, Nakao K.

J Biol Chem. 2012 Nov 23;287(48):40441-7. doi: 10.1074/jbc.M112.384545. Epub 2012 Sep 28.

PMID:
23024365
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inherited lipodystrophies and hypertriglyceridemia.

Simha V, Garg A.

Curr Opin Lipidol. 2009 Aug;20(4):300-8. doi: 10.1097/MOL.0b013e32832d4a33. Review.

PMID:
19494770
[PubMed - indexed for MEDLINE]

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