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Items: 1 to 20 of 210

1.

NFAT2 mediates high glucose-induced glomerular podocyte apoptosis through increased Bax expression.

Li R, Zhang L, Shi W, Zhang B, Liang X, Liu S, Wang W.

Exp Cell Res. 2013 Apr 15;319(7):992-1000. doi: 10.1016/j.yexcr.2013.01.007. Epub 2013 Jan 20.

PMID:
23340267
2.

NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice.

Zhang L, Li R, Shi W, Liang X, Liu S, Ye Z, Yu C, Chen Y, Zhang B, Wang W, Lai Y, Ma J, Li Z, Tan X.

Br J Pharmacol. 2013 Sep;170(2):426-39. doi: 10.1111/bph.12292.

3.

Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo.

Wang L, Chang JH, Paik SY, Tang Y, Eisner W, Spurney RF.

Mol Endocrinol. 2011 Aug;25(8):1376-86. doi: 10.1210/me.2011-0029. Epub 2011 May 26.

4.

Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis.

Wang XM, Yao M, Liu SX, Hao J, Liu QJ, Gao F.

Am J Physiol Renal Physiol. 2014 Jan;306(2):F205-13. doi: 10.1152/ajprenal.90005.2013. Epub 2013 Nov 13.

5.

Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism.

Liu W, Zhang Y, Hao J, Liu S, Liu Q, Zhao S, Shi Y, Duan H.

J Cell Biochem. 2012 Oct;113(10):3186-96. doi: 10.1002/jcb.24195. Erratum in: J Cell Biochem. 2014 Jul;115(7):1342.

PMID:
22614921
6.

The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury.

Zhang B, Shi W, Ma J, Sloan A, Faul C, Wei C, Reiser J, Yang Y, Liu S, Wang W.

J Mol Med (Berl). 2012 Dec;90(12):1407-20. doi: 10.1007/s00109-012-0960-6. Epub 2012 Sep 27. Erratum in: J Mol Med (Berl). 2012 Dec;90(12):1517.

7.

Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo.

Gui D, Guo Y, Wang F, Liu W, Chen J, Chen Y, Huang J, Wang N.

PLoS One. 2012;7(6):e39824. doi: 10.1371/journal.pone.0039824. Epub 2012 Jun 22.

8.

Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes.

Li Z, Xu J, Xu P, Liu S, Yang Z.

Cell Prolif. 2013 Feb;46(1):76-85. doi: 10.1111/cpr.12010.

PMID:
23294354
9.

Ubiquitination-dependent CARM1 degradation facilitates Notch1-mediated podocyte apoptosis in diabetic nephropathy.

Kim D, Lim S, Park M, Choi J, Kim J, Han H, Yoon K, Kim K, Lim J, Park S.

Cell Signal. 2014 Sep;26(9):1774-82. doi: 10.1016/j.cellsig.2014.04.008. Epub 2014 Apr 12.

PMID:
24726896
10.

Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway.

Li G, Li Y, Liu S, Shi Y, Chi Y, Liu G, Shan T.

J Cell Biochem. 2013 Sep;114(9):2101-13. doi: 10.1002/jcb.24559.

PMID:
23553804
11.
12.

Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes.

Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CR, Geraldes P.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1188-98. doi: 10.1152/ajpendo.00560.2012. Epub 2013 Mar 26.

13.

Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.

Nijenhuis T, Sloan AJ, Hoenderop JG, Flesche J, van Goor H, Kistler AD, Bakker M, Bindels RJ, de Boer RA, Möller CC, Hamming I, Navis G, Wetzels JF, Berden JH, Reiser J, Faul C, van der Vlag J.

Am J Pathol. 2011 Oct;179(4):1719-32. doi: 10.1016/j.ajpath.2011.06.033. Epub 2011 Aug 11.

14.

High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway.

Zhang Y, Li H, Hao J, Zhou Y, Liu W.

Exp Cell Res. 2014 Aug 15;326(2):219-29. doi: 10.1016/j.yexcr.2014.04.014. Epub 2014 Apr 24.

PMID:
24768698
15.

Astragaloside IV prevents high glucose-induced podocyte apoptosis via downregulation of TRPC6.

Yao XM, Liu YJ, Wang YM, Wang H, Zhu BB, Liang YP, Yao WG, Yu H, Wang NS, Zhang XM, Peng W.

Mol Med Rep. 2016 Jun;13(6):5149-56. doi: 10.3892/mmr.2016.5167. Epub 2016 Apr 22.

PMID:
27109610
17.
18.

NFAT2 is implicated in corticosterone-induced rat Leydig cell apoptosis.

Chai WR, Wang Q, Gao HB.

Asian J Androl. 2007 Sep;9(5):623-33.

19.

Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions.

Li Z, Zhang L, Shi W, Chen Y, Zhang H, Liu S, Liang X, Ling T, Yu C, Huang Z, Tan X, Zhao X, Ye Z, Zhang B, Wang W, Li R, Ma J.

Mol Med Rep. 2015 Nov;12(5):6849-54. doi: 10.3892/mmr.2015.4295. Epub 2015 Sep 7.

PMID:
26352002
20.

Glucose specifically regulates TRPC6 expression in the podocyte in an AngII-dependent manner.

Sonneveld R, van der Vlag J, Baltissen MP, Verkaart SA, Wetzels JF, Berden JH, Hoenderop JG, Nijenhuis T.

Am J Pathol. 2014 Jun;184(6):1715-26. doi: 10.1016/j.ajpath.2014.02.008. Epub 2014 Apr 13.

PMID:
24731445
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