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Results: 1 to 20 of 105

1.

Understanding drugs and diseases by systems biology?

Schneider HC, Klabunde T.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1168-76. doi: 10.1016/j.bmcl.2012.12.031. Epub 2012 Dec 26. Review.

PMID:
23337596
[PubMed - indexed for MEDLINE]
Free Article
2.

Advances in systems biology are enhancing our understanding of disease and moving us closer to novel disease treatments.

Schadt EE, Zhang B, Zhu J.

Genetica. 2009 Jun;136(2):259-69. doi: 10.1007/s10709-009-9359-x. Epub 2009 Apr 11. Review.

PMID:
19363597
[PubMed - indexed for MEDLINE]
3.

Proteomics and systems biology: application in drug discovery and development.

Chakravarti B, Mallik B, Chakravarti DN.

Methods Mol Biol. 2010;662:3-28. doi: 10.1007/978-1-60761-800-3_1. Review.

PMID:
20824464
[PubMed - indexed for MEDLINE]
4.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
[PubMed - indexed for MEDLINE]
5.
6.

Genome-scale modeling of human metabolism - a systems biology approach.

Mardinoglu A, Gatto F, Nielsen J.

Biotechnol J. 2013 Sep;8(9):985-96. doi: 10.1002/biot.201200275. Epub 2013 Apr 24. Review.

PMID:
23613448
[PubMed - indexed for MEDLINE]
7.

Biological complexity and drug discovery: a practical systems biology approach.

Berg EL, Kunkel EJ, Hytopoulos E.

Syst Biol (Stevenage). 2005 Dec;152(4):201-6.

PMID:
16986261
[PubMed - indexed for MEDLINE]
8.

Systems and Synthetic biology: tackling genetic networks and complex diseases.

Cuccato G, Della Gatta G, di Bernardo D.

Heredity (Edinb). 2009 Jun;102(6):527-32. doi: 10.1038/hdy.2009.18. Epub 2009 Mar 4. Review.

PMID:
19259117
[PubMed - indexed for MEDLINE]
Free Article
9.

Systems biology in drug discovery.

Butcher EC, Berg EL, Kunkel EJ.

Nat Biotechnol. 2004 Oct;22(10):1253-9. Review.

PMID:
15470465
[PubMed - indexed for MEDLINE]
10.

Systems biology impact on antiepileptic drug discovery.

Margineanu DG.

Epilepsy Res. 2012 Feb;98(2-3):104-15. doi: 10.1016/j.eplepsyres.2011.10.006. Epub 2011 Nov 3. Review.

PMID:
22055355
[PubMed - indexed for MEDLINE]
11.

Applying systems biology in drug discovery and development.

Galizzi JP, Lockhart BP, Bril A.

Drug Metabol Drug Interact. 2013;28(2):67-78. doi: 10.1515/dmdi-2013-0002. Review.

PMID:
23612649
[PubMed - indexed for MEDLINE]
12.

Advanced systems biology methods in drug discovery and translational biomedicine.

Zou J, Zheng MW, Li G, Su ZG.

Biomed Res Int. 2013;2013:742835. doi: 10.1155/2013/742835. Epub 2013 Sep 19. Review.

PMID:
24171171
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Network-based approaches in drug discovery and early development.

Harrold JM, Ramanathan M, Mager DE.

Clin Pharmacol Ther. 2013 Dec;94(6):651-8. doi: 10.1038/clpt.2013.176. Epub 2013 Sep 11. Review.

PMID:
24025802
[PubMed - indexed for MEDLINE]
14.

Comparative systems biology: from bacteria to man.

Teusink B, Westerhoff HV, Bruggeman FJ.

Wiley Interdiscip Rev Syst Biol Med. 2010 Sep-Oct;2(5):518-32. doi: 10.1002/wsbm.74. Review.

PMID:
20836045
[PubMed - indexed for MEDLINE]
15.

Potential of a cytomics top-down strategy for drug discovery.

Tárnok A, Pierzchalski A, Valet G.

Curr Med Chem. 2010;17(16):1719-29. Review.

PMID:
20345347
[PubMed - indexed for MEDLINE]
16.

Network analyses in systems pharmacology.

Berger SI, Iyengar R.

Bioinformatics. 2009 Oct 1;25(19):2466-72. doi: 10.1093/bioinformatics/btp465. Epub 2009 Jul 30. Review.

PMID:
19648136
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Considerations for the sensible use of rodent models of inflammatory disease in predicting efficacy of new biological therapeutics in the clinic.

Arnett HA, Viney JL.

Adv Drug Deliv Rev. 2007 Sep 30;59(11):1084-92. Epub 2007 Aug 16. Review.

PMID:
17804112
[PubMed - indexed for MEDLINE]
18.

Systems approaches to polypharmacology and drug discovery.

Boran AD, Iyengar R.

Curr Opin Drug Discov Devel. 2010 May;13(3):297-309. Review.

PMID:
20443163
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Unveiling the role of network and systems biology in drug discovery.

Pujol A, Mosca R, Farrés J, Aloy P.

Trends Pharmacol Sci. 2010 Mar;31(3):115-23. doi: 10.1016/j.tips.2009.11.006. Epub 2010 Feb 1. Review.

PMID:
20117850
[PubMed - indexed for MEDLINE]
20.

Green systems biology - From single genomes, proteomes and metabolomes to ecosystems research and biotechnology.

Weckwerth W.

J Proteomics. 2011 Dec 10;75(1):284-305. doi: 10.1016/j.jprot.2011.07.010. Epub 2011 Jul 23. Review.

PMID:
21802534
[PubMed - indexed for MEDLINE]
Free Article
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