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Prunellae spica extract contains antagonists for human endothelin receptors.

Chen CY, Ho LT, Yang FY, Juan CC, Au LC.

Am J Chin Med. 2013;41(1):85-98. doi: 10.1142/S0192415X13500079.


Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy.

Andrade D, Serra R, Svensjö E, Lima AP, Ramos ES Jr, Fortes FS, Morandini AC, Morandi V, Soeiro Mde N, Tanowitz HB, Scharfstein J.

Br J Pharmacol. 2012 Mar;165(5):1333-47. doi: 10.1111/j.1476-5381.2011.01609.x.


Chronic activation of endothelin B receptors: new model of experimental hypertension.

Fink G, Li M, Lau Y, Osborn J, Watts S.

Hypertension. 2007 Sep;50(3):512-8. Epub 2007 Jul 30.


Endothelin A and B receptors of preglomerular vascular smooth muscle cells.

Fellner SK, Arendshorst WJ.

Kidney Int. 2004 May;65(5):1810-7.


Dual constrictor and dilator actions of ET(B) receptors in the rat renal microcirculation: interactions with ET(A) receptors.

Just A, Olson AJ, Arendshorst WJ.

Am J Physiol Renal Physiol. 2004 Apr;286(4):F660-8. Epub 2003 Dec 16.


An endothelin type A receptor-expressing cell to characterize endothelin-1 binding and screen antagonist.

Juan CC, Au LC, Yang FY, Yang DM, Ho LT.

Anal Biochem. 2008 Aug 1;379(1):27-31. doi: 10.1016/j.ab.2008.04.020. Epub 2008 Apr 15.


ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Gα(q/11).

Montmayeur JP, Barr TP, Kam SA, Packer SJ, Strichartz GR.

Pharmacol Res. 2011 Sep;64(3):258-67. doi: 10.1016/j.phrs.2011.04.003. Epub 2011 Apr 14.


Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways.

Maguire JJ, Kuc RE, Pell VR, Green A, Brown M, Kumar S, Wehrman T, Quinn E, Davenport AP.

Life Sci. 2012 Oct 15;91(13-14):544-9. doi: 10.1016/j.lfs.2012.03.021. Epub 2012 Mar 27.


ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo.

Thai TL, Arendshorst WJ.

Am J Physiol Renal Physiol. 2008 Aug;295(2):F360-8. doi: 10.1152/ajprenal.00512.2007. Epub 2008 Jun 4.


Impaired endothelin calcium signaling coupled to endothelin type B receptors in penile arteries from insulin-resistant obese Zucker rats.

Contreras C, Sánchez A, Martínez P, Climent B, Benedito S, García-Sacristán A, Hernández M, Prieto D.

J Sex Med. 2013 Sep;10(9):2141-53. doi: 10.1111/jsm.12234. Epub 2013 Jul 22.


Interactions of endothelin-1 with dexamethasone in primary cultured human trabecular meshwork cells.

Zhang X, Clark AF, Yorio T.

Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5301-8.


Pharmacologic characterization of S-1255, a highly potent and orally active endothelin A receptor antagonist.

Iwasaki T, Mihara S, Shimamura T, Kawakami M, Masui M, Hayasaki-Kajiwara Y, Naya N, Ninomiya M, Fujimoto M, Nakajima M.

J Cardiovasc Pharmacol. 2001 Apr;37(4):471-82.


Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling.

El-Mas MM, Helmy MW, Ali RM, El-Gowelli HM.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):1-7. doi: 10.1016/j.taap.2015.01.018. Epub 2015 Feb 3.


Differential coupling of human endothelin type A receptor to G(q/11) and G(12) proteins: the functional significance of receptor expression level in generating multiple receptor signaling.

Horinouchi T, Asano H, Higa T, Nishimoto A, Nishiya T, Muramatsu I, Miwa S.

J Pharmacol Sci. 2009 Dec;111(4):338-51. Epub 2009 Nov 27.


Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca²⁺]i in mesenteric microvessels of pregnant rats.

Mazzuca MQ, Dang Y, Khalil RA.

Br J Pharmacol. 2013 Jul;169(6):1335-51. doi: 10.1111/bph.12225.


Metabolic syndrome and endothelin-1 mediated vasoconstrictor tone in overweight/obese adults.

Rocha NG, Templeton DL, Greiner JJ, Stauffer BL, DeSouza CA.

Metabolism. 2014 Jul;63(7):951-6. doi: 10.1016/j.metabol.2014.04.007. Epub 2014 Apr 18.


Pharmacological properties of J-104132 (L-753,037), a potent, orally active, mixed ETA/ETB endothelin receptor antagonist.

Nishikibe M, Ohta H, Okada M, Ishikawa K, Hayama T, Fukuroda T, Noguchi K, Saito M, Kanoh T, Ozaki S, Kamei T, Hara K, William D, Kivlighn S, Krause S, Gabel R, Zingaro G, Nolan N, O'Brien J, Clayton F, Lynch J, Pettibone D, Siegl P.

J Pharmacol Exp Ther. 1999 Jun;289(3):1262-70.

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