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Items: 1 to 20 of 139

1.

Membrane microdomains and cytoskeleton organization shape and regulate the IL-7 receptor signalosome in human CD4 T-cells.

Tamarit B, Bugault F, Pillet AH, Lavergne V, Bochet P, Garin N, Schwarz U, Thèze J, Rose T.

J Biol Chem. 2013 Mar 22;288(12):8691-701. doi: 10.1074/jbc.M113.449918. Epub 2013 Jan 17.

2.

IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork.

Pillet AH, Lavergne V, Pasquier V, Gesbert F, Thèze J, Rose T.

J Mol Biol. 2010 Nov 12;403(5):671-92. doi: 10.1016/j.jmb.2010.08.056. Epub 2010 Sep 21.

PMID:
20816854
3.

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.

Kirken RA, Rui H, Malabarba MG, Howard OM, Kawamura M, O'Shea JJ, Farrar WL.

Cytokine. 1995 Oct;7(7):689-700.

PMID:
8580378
4.

IL-6 activates STAT5 in T cells.

Tormo AJ, Letellier MC, Sharma M, Elson G, Crabé S, Gauchat JF.

Cytokine. 2012 Nov;60(2):575-82. doi: 10.1016/j.cyto.2012.07.002. Epub 2012 Jul 31.

PMID:
22854263
5.
7.

Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation.

Delaguillaumie A, Harriague J, Kohanna S, Bismuth G, Rubinstein E, Seigneuret M, Conjeaud H.

J Cell Sci. 2004 Oct 15;117(Pt 22):5269-82. Epub 2004 Sep 28.

8.

T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex.

Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C, Kamata T, Shin T, Seki N, Suzuki S, Taniguchi M, Nakayama T.

J Exp Med. 2000 Jun 5;191(11):1869-79.

9.

The interleukin-4 receptor activates STAT5 by a mechanism that relies upon common gamma-chain.

Lischke A, Moriggl R, Brändlein S, Berchtold S, Kammer W, Sebald W, Groner B, Liu X, Hennighausen L, Friedrich K.

J Biol Chem. 1998 Nov 20;273(47):31222-9.

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12.

Interleukin-7 promotes the survival of human CD4+ effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway.

Chetoui N, Boisvert M, Gendron S, Aoudjit F.

Immunology. 2010 Jul;130(3):418-26. doi: 10.1111/j.1365-2567.2009.03244.x. Epub 2010 May 4.

13.

CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation.

Martín P, Gómez M, Lamana A, Cruz-Adalia A, Ramírez-Huesca M, Ursa MA, Yáñez-Mo M, Sánchez-Madrid F.

Mol Cell Biol. 2010 Oct;30(20):4877-89. doi: 10.1128/MCB.00456-10. Epub 2010 Aug 9.

14.

Regulation of interleukin-2 signaling by fatty acids in human lymphocytes.

Gorjão R, Hirabara SM, de Lima TM, Cury-Boaventura MF, Curi R.

J Lipid Res. 2007 Sep;48(9):2009-19. Epub 2007 Jun 25. Retraction in: J Lipid Res. 2013 Mar;54(3):869.

15.

Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.

Rodriguez G, Ross JA, Nagy ZS, Kirken RA.

J Biol Chem. 2013 Mar 8;288(10):7137-46. doi: 10.1074/jbc.M112.408765. Epub 2013 Jan 22.

16.

Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.

Ross JA, Cheng H, Nagy ZS, Frost JA, Kirken RA.

J Biol Chem. 2010 Feb 5;285(6):3582-91. doi: 10.1074/jbc.M109.053843. Epub 2009 Nov 18.

17.

Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling.

Rochman Y, Kashyap M, Robinson GW, Sakamoto K, Gomez-Rodriguez J, Wagner KU, Leonard WJ.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19455-60. doi: 10.1073/pnas.1008271107. Epub 2010 Oct 25.

18.

Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response.

Rose T, Pillet AH, Lavergne V, Tamarit B, Lenormand P, Rousselle JC, Namane A, Thèze J.

J Biol Chem. 2010 May 14;285(20):14898-908. doi: 10.1074/jbc.M110.104232. Epub 2010 Feb 18.

19.

Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.

Burnham ME, Esnault S, Roti Roti EC, Bates ME, Bertics PJ, Denlinger LC.

PLoS One. 2014 Aug 14;9(8):e103122. doi: 10.1371/journal.pone.0103122. eCollection 2014.

20.

FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.

Rani A, Greenlaw R, Runglall M, Jurcevic S, John S.

PLoS One. 2014 Feb 28;9(2):e90370. doi: 10.1371/journal.pone.0090370. eCollection 2014.

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