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Items: 1 to 20 of 85

1.

Cancer genetics and the cardiotoxicity of the therapeutics.

Lal H, Kolaja KL, Force T.

J Am Coll Cardiol. 2013 Jan 22;61(3):267-74. doi: 10.1016/j.jacc.2012.05.066. Review.

2.

Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes.

Force T, Kolaja KL.

Nat Rev Drug Discov. 2011 Feb;10(2):111-26. doi: 10.1038/nrd3252. Review.

PMID:
21283106
3.

Molecular mechanisms of cardiovascular toxicity of targeted cancer therapeutics.

Cheng H, Force T.

Circ Res. 2010 Jan 8;106(1):21-34. doi: 10.1161/CIRCRESAHA.109.206920. Review.

4.

Why do kinase inhibitors cause cardiotoxicity and what can be done about it?

Cheng H, Force T.

Prog Cardiovasc Dis. 2010 Sep-Oct;53(2):114-20. doi: 10.1016/j.pcad.2010.06.006. Review.

PMID:
20728698
5.

Cancer treatment-induced cardiotoxicity: a cardiac stem cell disease?

Prezioso L, Tanzi S, Galaverna F, Frati C, Testa B, Savi M, Graiani G, Lagrasta C, Cavalli S, Galati S, Madeddu D, Lodi Rizzini E, Ferraro F, Musso E, Stilli D, Urbanek K, Piegari E, De Angelis A, Maseri A, Rossi F, Quaini E, Quaini F.

Cardiovasc Hematol Agents Med Chem. 2010 Jan;8(1):55-75. Review.

PMID:
20210776
6.

Review: cardiovascular toxicities due to molecularly targeted cancer therapeutics.

Chintalgattu V, Khakoo AY.

Clin Adv Hematol Oncol. 2010 Feb;8(2):133-5. Review. No abstract available.

PMID:
20386535
7.

Cardiotoxicity associated with targeting kinase pathways in cancer.

Mellor HR, Bell AR, Valentin JP, Roberts RR.

Toxicol Sci. 2011 Mar;120(1):14-32. doi: 10.1093/toxsci/kfq378. Epub 2010 Dec 22. Review.

8.

Therapeutic protein kinase inhibitors.

Grant SK.

Cell Mol Life Sci. 2009 Apr;66(7):1163-77. doi: 10.1007/s00018-008-8539-7. Review.

PMID:
19011754
9.

Selective antagonism of anticancer drugs for side-effect removal.

Fernández A, Sessel S.

Trends Pharmacol Sci. 2009 Aug;30(8):403-10. doi: 10.1016/j.tips.2009.06.001.

PMID:
19595465
10.

Tyrosine kinase inhibitor (TKI)-induced cardiotoxicity: approaches to narrow the gaps between preclinical safety evaluation and clinical outcome.

Yang B, Papoian T.

J Appl Toxicol. 2012 Dec;32(12):945-51. doi: 10.1002/jat.2813. Epub 2012 Sep 10. Review.

PMID:
22961481
11.

Point mutations of protein kinases and individualised cancer therapy.

Davies M, Hennessy B, Mills GB.

Expert Opin Pharmacother. 2006 Nov;7(16):2243-61. Review.

PMID:
17059381
12.

Kinase inhibitor conjugates.

Harmsen S, Kok RJ.

Curr Pharm Des. 2012;18(20):2891-900. Review.

PMID:
22571658
13.
14.

Chemotherapy-associated cardiotoxicity: how often does it really occur and how can it be prevented?

Witteles RM, Fowler MB, Telli ML.

Heart Fail Clin. 2011 Jul;7(3):333-44. doi: 10.1016/j.hfc.2011.03.005. Epub 2011 May 14. Review.

PMID:
21749885
15.

Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.

Gollob JA, Wilhelm S, Carter C, Kelley SL.

Semin Oncol. 2006 Aug;33(4):392-406. Review.

PMID:
16890795
16.

Introduction to cardiotoxicity review series.

Force T.

Circ Res. 2010 Jan 8;106(1):19-20. doi: 10.1161/CIRCRESAHA.109.210724. No abstract available.

17.

The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones.

Workman P.

Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S45-56. Epub 2003 Jun 18. Review.

PMID:
12819933
18.

Is there a future for Aurora kinase inhibitors for anticancer therapy?

Carpinelli P, Moll J.

Curr Opin Drug Discov Devel. 2009 Jul;12(4):533-42. Review.

PMID:
19562649
19.

New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.

Faivre S, Djelloul S, Raymond E.

Semin Oncol. 2006 Aug;33(4):407-20. Review.

PMID:
16890796
20.

Cardiotoxicity of the new cancer therapeutics--mechanisms of, and approaches to, the problem.

Force T, Kerkelä R.

Drug Discov Today. 2008 Sep;13(17-18):778-84. doi: 10.1016/j.drudis.2008.05.011. Epub 2008 Sep 2. Review.

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