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Results: 1 to 20 of 98

1.

Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.

Wu S, Kasim V, Kano MR, Tanaka S, Ohba S, Miura Y, Miyata K, Liu X, Matsuhashi A, Chung UI, Yang L, Kataoka K, Nishiyama N, Miyagishi M.

Cancer Res. 2013 Mar 15;73(6):1787-99. doi: 10.1158/0008-5472.CAN-12-0366. Epub 2013 Jan 17.

PMID:
23328582
[PubMed - indexed for MEDLINE]
Free Article
2.

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia.

Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS.

Mol Cell Biol. 2003 Jan;23(1):359-69.

PMID:
12482987
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha.

Nardinocchi L, Puca R, Sacchi A, Rechavi G, Givol D, D'Orazi G.

PLoS One. 2009 Aug 28;4(8):e6819. doi: 10.1371/journal.pone.0006819.

PMID:
19714248
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.

Nardinocchi L, Puca R, Sacchi A, D'Orazi G.

Mol Cancer. 2009 Jan 7;8:1. doi: 10.1186/1476-4598-8-1.

PMID:
19128456
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB.

Rohwer N, Dame C, Haugstetter A, Wiedenmann B, Detjen K, Schmitt CA, Cramer T.

PLoS One. 2010 Aug 10;5(8):e12038. doi: 10.1371/journal.pone.0012038.

PMID:
20706634
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Activating transcription factor 2 increases transactivation and protein stability of hypoxia-inducible factor 1alpha in hepatocytes.

Choi JH, Cho HK, Choi YH, Cheong J.

Biochem J. 2009 Nov 11;424(2):285-96. doi: 10.1042/BJ20090371.

PMID:
19712049
[PubMed - indexed for MEDLINE]
Free Article
7.

Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.

Jung DB, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim YC, Ahn KS, Chen CY, Kim SH.

Biol Pharm Bull. 2011;34(6):850-5.

PMID:
21628883
[PubMed - indexed for MEDLINE]
Free Article
8.

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

Kaluzová M, Kaluz S, Lerman MI, Stanbridge EJ.

Mol Cell Biol. 2004 Jul;24(13):5757-66.

PMID:
15199132
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A.

Genes Dev. 2000 Jan 1;14(1):34-44.

PMID:
10640274
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy.

de Nigris F, Crudele V, Giovane A, Casamassimi A, Giordano A, Garban HJ, Cacciatore F, Pentimalli F, Marquez-Garban DC, Petrillo A, Cito L, Sommese L, Fiore A, Petrillo M, Siani A, Barbieri A, Arra C, Rengo F, Hayashi T, Al-Omran M, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14484-9. doi: 10.1073/pnas.1008256107. Epub 2010 Jul 26.

PMID:
20660740
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

GDF-15 promotes angiogenesis through modulating p53/HIF-1α signaling pathway in hypoxic human umbilical vein endothelial cells.

Song H, Yin D, Liu Z.

Mol Biol Rep. 2012 Apr;39(4):4017-22. doi: 10.1007/s11033-011-1182-7. Epub 2011 Jul 20.

PMID:
21773947
[PubMed - indexed for MEDLINE]
12.

Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.

Park SS, Bae I, Lee YJ.

J Cell Biochem. 2008 Apr 15;103(6):1989-98.

PMID:
17973296
[PubMed - indexed for MEDLINE]
13.

Phosphatidylinositol 3'-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1(alpha) and vascular endothelial growth factor expression.

Xue Y, Li NL, Yang JY, Chen Y, Yang LL, Liu WC.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2169-76. doi: 10.1152/ajpheart.00970.2010. Epub 2011 Feb 25.

PMID:
21357506
[PubMed - indexed for MEDLINE]
Free Article
14.

HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation.

Nardinocchi L, Puca R, D'Orazi G.

Aging (Albany NY). 2011 Jan;3(1):33-43.

PMID:
21248371
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

Schmid T, Zhou J, Köhl R, Brüne B.

Biochem J. 2004 May 15;380(Pt 1):289-95.

PMID:
14992692
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5.

Lee SJ, No YR, Dang DT, Dang LH, Yang VW, Shim H, Yun CC.

J Biol Chem. 2013 Aug 30;288(35):25244-53. doi: 10.1074/jbc.M113.489708. Epub 2013 Jul 23.

PMID:
23880760
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pretreatment evaluation of combined HIF-1alpha, p53 and p21 expression is a useful and sensitive indicator of response to radiation and chemotherapy in esophageal cancer.

Sohda M, Ishikawa H, Masuda N, Kato H, Miyazaki T, Nakajima M, Fukuchi M, Manda R, Fukai Y, Sakurai H, Kuwano H.

Int J Cancer. 2004 Jul 20;110(6):838-44.

PMID:
15170665
[PubMed - indexed for MEDLINE]
18.

Effects of YC-1 on hypoxia-inducible factor 1 alpha in hypoxic human bladder transitional carcinoma cell line T24 cells.

Li Y, Zhao X, Tang H, Zhong Z, Zhang L, Xu R, Li S, Wang Y.

Urol Int. 2012;88(1):95-101. doi: 10.1159/000331881. Epub 2011 Oct 25.

PMID:
22041818
[PubMed - indexed for MEDLINE]
19.

[The relationship between P53 and hypoxia-inducible transcription factor-1alpha in the placenta of patient with intrahepatic cholestasis of pregnancy under acute hypoxic condition].

Hu YY, Wang XD, Liu SY.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2006 Nov;37(6):901-3, 942. Chinese.

PMID:
17236590
[PubMed - indexed for MEDLINE]
20.

Effect of hypoxia-inducible factor-1alpha on transcription of survivin in non-small cell lung cancer.

Chen YQ, Zhao CL, Li W.

J Exp Clin Cancer Res. 2009 Feb 26;28:29. doi: 10.1186/1756-9966-28-29.

PMID:
19245702
[PubMed - indexed for MEDLINE]
Free PMC Article
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