Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 127

1.

Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate.

Yasuo M, Mizuno S, Allegood J, Kraskauskas D, Bogaard HJ, Spiegel S, Voelkel NF.

PLoS One. 2013;8(1):e53927. doi: 10.1371/journal.pone.0053927. Epub 2013 Jan 11.

PMID:
23326540
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.

Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, Berdyshev EV, Petrache I.

Am J Respir Crit Care Med. 2010 Feb 15;181(4):344-52. doi: 10.1164/rccm.200906-0826OC. Epub 2009 Dec 3.

PMID:
19965812
[PubMed - indexed for MEDLINE]
3.

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.

Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM.

Nat Med. 2005 May;11(5):491-8. Epub 2005 Apr 24.

PMID:
15852018
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inhibition of histone deacetylase causes emphysema.

Mizuno S, Yasuo M, Bogaard HJ, Kraskauskas D, Natarajan R, Voelkel NF.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L402-13. doi: 10.1152/ajplung.00207.2010. Epub 2010 Dec 17.

PMID:
21224215
[PubMed - indexed for MEDLINE]
Free Article
5.

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.

Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA.

J Biol Chem. 2005 Jul 29;280(30):27879-87. Epub 2005 Jun 9.

PMID:
15946935
[PubMed - indexed for MEDLINE]
Free Article
6.

A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.

Abuhusain HJ, Matin A, Qiao Q, Shen H, Kain N, Day BW, Stringer BW, Daniels B, Laaksonen MA, Teo C, McDonald KL, Don AS.

J Biol Chem. 2013 Dec 27;288(52):37355-64. doi: 10.1074/jbc.M113.494740. Epub 2013 Nov 21.

PMID:
24265321
[PubMed - indexed for MEDLINE]
7.

A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model.

Wiegman CH, Li F, Clarke CJ, Jazrawi E, Kirkham P, Barnes PJ, Adcock IM, Chung KF.

Clin Sci (Lond). 2014 Mar;126(6):425-40. doi: 10.1042/CS20130039.

PMID:
24040961
[PubMed - indexed for MEDLINE]
8.

De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.

Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V.

Cell Signal. 2006 Oct;18(10):1779-92. Epub 2006 Mar 10.

PMID:
16529909
[PubMed - indexed for MEDLINE]
9.

Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets.

Melendez AJ.

Biochim Biophys Acta. 2008 Jan;1784(1):66-75. Epub 2007 Aug 14. Review.

PMID:
17913601
[PubMed - indexed for MEDLINE]
Free Article
10.

Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons.

Zhang YH, Vasko MR, Nicol GD.

J Physiol. 2006 Aug 15;575(Pt 1):101-13. Epub 2006 Jun 1.

PMID:
16740613
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.

Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JG, Natarajan V.

J Biol Chem. 2009 Feb 27;284(9):5467-77. doi: 10.1074/jbc.M805186200. Epub 2009 Jan 1.

PMID:
19119142
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hypoxia-inducible factors and sphingosine 1-phosphate signaling.

Cuvillier O, Ader I.

Anticancer Agents Med Chem. 2011 Nov;11(9):854-62. Review.

PMID:
21707486
[PubMed - indexed for MEDLINE]
13.

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells.

Baran Y, Salas A, Senkal CE, Gunduz U, Bielawski J, Obeid LM, Ogretmen B.

J Biol Chem. 2007 Apr 13;282(15):10922-34. Epub 2007 Feb 15.

PMID:
17303574
[PubMed - indexed for MEDLINE]
Free Article
14.

Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.

Bassi R, Anelli V, Giussani P, Tettamanti G, Viani P, Riboni L.

Glia. 2006 Apr 15;53(6):621-30.

PMID:
16470810
[PubMed - indexed for MEDLINE]
15.

The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes.

Karliner JS, Honbo N, Summers K, Gray MO, Goetzl EJ.

J Mol Cell Cardiol. 2001 Sep;33(9):1713-7.

PMID:
11549349
[PubMed - indexed for MEDLINE]
16.

1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase.

Kleuser B, Cuvillier O, Spiegel S.

Cancer Res. 1998 May 1;58(9):1817-24.

PMID:
9581819
[PubMed - indexed for MEDLINE]
Free Article
17.

Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

Schnitzer SE, Weigert A, Zhou J, Brüne B.

Mol Cancer Res. 2009 Mar;7(3):393-401. doi: 10.1158/1541-7786.MCR-08-0156. Epub 2009 Feb 24.

PMID:
19240180
[PubMed - indexed for MEDLINE]
Free Article
18.

Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy.

Huwiler A, Pfeilschifter J.

Curr Pharm Des. 2006;12(35):4625-35.

PMID:
17168766
[PubMed - indexed for MEDLINE]
19.

Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia.

Doyle T, Chen Z, Obeid LM, Salvemini D.

Neurosci Lett. 2011 Jul 15;499(1):4-8. doi: 10.1016/j.neulet.2011.05.018. Epub 2011 May 13.

PMID:
21605625
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

Anelli V, Gault CR, Cheng AB, Obeid LM.

J Biol Chem. 2008 Feb 8;283(6):3365-75. Epub 2007 Nov 30.

PMID:
18055454
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk