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Results: 1 to 20 of 135

1.

UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.

Schamber-Reis BL, Petritus PM, Caetano BC, Martinez ER, Okuda K, Golenbock D, Scott P, Gazzinelli RT.

J Biol Chem. 2013 Mar 8;288(10):7127-36. doi: 10.1074/jbc.M112.407684. Epub 2013 Jan 16.

PMID:
23325805
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking.

Fukui R, Saitoh S, Kanno A, Onji M, Shibata T, Ito A, Onji M, Matsumoto M, Akira S, Yoshida N, Miyake K.

Immunity. 2011 Jul 22;35(1):69-81. doi: 10.1016/j.immuni.2011.05.010. Epub 2011 Jun 16.

PMID:
21683627
[PubMed - indexed for MEDLINE]
Free Article
3.

Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.

Caetano BC, Carmo BB, Melo MB, Cerny A, dos Santos SL, Bartholomeu DC, Golenbock DT, Gazzinelli RT.

J Immunol. 2011 Aug 15;187(4):1903-11. doi: 10.4049/jimmunol.1003911. Epub 2011 Jul 13.

PMID:
21753151
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.

Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K.

J Exp Med. 2009 Jun 8;206(6):1339-50. doi: 10.1084/jem.20082316. Epub 2009 May 18.

PMID:
19451267
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.

Andrade WA, Souza Mdo C, Ramos-Martinez E, Nagpal K, Dutra MS, Melo MB, Bartholomeu DC, Ghosh S, Golenbock DT, Gazzinelli RT.

Cell Host Microbe. 2013 Jan 16;13(1):42-53. doi: 10.1016/j.chom.2012.12.003. Epub 2013 Jan 3.

PMID:
23290966
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

Kim YM, Brinkmann MM, Paquet ME, Ploegh HL.

Nature. 2008 Mar 13;452(7184):234-8. doi: 10.1038/nature06726. Epub 2008 Feb 27.

PMID:
18305481
[PubMed - indexed for MEDLINE]
7.

UNC93B1 mediates host resistance to infection with Toxoplasma gondii.

Melo MB, Kasperkovitz P, Cerny A, Könen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT.

PLoS Pathog. 2010 Aug 26;6(8):e1001071. doi: 10.1371/journal.ppat.1001071.

PMID:
20865117
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling.

Kim J, Huh J, Hwang M, Kwon EH, Jung DJ, Brinkmann MM, Jang MH, Ploegh HL, Kim YM.

J Immunol. 2013 May 15;190(10):5287-95. doi: 10.4049/jimmunol.1202767. Epub 2013 Apr 12.

PMID:
23585677
[PubMed - indexed for MEDLINE]
Free Article
9.

A new subset of CD103+CD8alpha+ dendritic cells in the small intestine expresses TLR3, TLR7, and TLR9 and induces Th1 response and CTL activity.

Fujimoto K, Karuppuchamy T, Takemura N, Shimohigoshi M, Machida T, Haseda Y, Aoshi T, Ishii KJ, Akira S, Uematsu S.

J Immunol. 2011 Jun 1;186(11):6287-95. doi: 10.4049/jimmunol.1004036. Epub 2011 Apr 27.

PMID:
21525388
[PubMed - indexed for MEDLINE]
Free Article
10.

Regulatory molecules required for nucleotide-sensing Toll-like receptors.

Saitoh S, Miyake K.

Immunol Rev. 2009 Jan;227(1):32-43. doi: 10.1111/j.1600-065X.2008.00729.x. Review.

PMID:
19120473
[PubMed - indexed for MEDLINE]
11.

TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions.

Abou Fakher FH, Rachinel N, Klimczak M, Louis J, Doyen N.

J Immunol. 2009 Feb 1;182(3):1386-96.

PMID:
19155485
[PubMed - indexed for MEDLINE]
Free Article
12.

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B.

Nat Immunol. 2006 Feb;7(2):156-64. Epub 2006 Jan 15.

PMID:
16415873
[PubMed - indexed for MEDLINE]
13.

Leishmania expressed lipophosphoglycan interacts with Toll-like receptor (TLR)-2 to decrease TLR-9 expression and reduce anti-leishmanial responses.

Srivastava S, Pandey SP, Jha MK, Chandel HS, Saha B.

Clin Exp Immunol. 2013 Jun;172(3):403-9. doi: 10.1111/cei.12074.

PMID:
23600828
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Toll-like receptor 7 mediates early innate immune responses to malaria.

Baccarella A, Fontana MF, Chen EC, Kim CC.

Infect Immun. 2013 Dec;81(12):4431-42. doi: 10.1128/IAI.00923-13. Epub 2013 Sep 16.

PMID:
24042114
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists.

Pohar J, Pirher N, Benčina M, Manček-Keber M, Jerala R.

J Biol Chem. 2013 Jan 4;288(1):442-54. doi: 10.1074/jbc.M112.413922. Epub 2012 Nov 19.

PMID:
23166319
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis.

Liese J, Schleicher U, Bogdan C.

Eur J Immunol. 2007 Dec;37(12):3424-34.

PMID:
18034422
[PubMed - indexed for MEDLINE]
17.

UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection.

Crane MJ, Gaddi PJ, Salazar-Mather TP.

PLoS One. 2012;7(6):e39161. doi: 10.1371/journal.pone.0039161. Epub 2012 Jun 18.

PMID:
22723955
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major.

Artis D, Speirs K, Joyce K, Goldschmidt M, Caamaño J, Hunter CA, Scott P.

J Immunol. 2003 Feb 15;170(4):1995-2003.

PMID:
12574369
[PubMed - indexed for MEDLINE]
Free Article
19.

Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response.

Muraille E, De Trez C, Brait M, De Baetselier P, Leo O, Carlier Y.

J Immunol. 2003 Apr 15;170(8):4237-41.

PMID:
12682257
[PubMed - indexed for MEDLINE]
Free Article
20.

Toll-like receptors and CD40 modulate each other's expression affecting Leishmania major infection.

Chandel HS, Pandey SP, Shukla D, Lalsare K, Selvaraj SK, Jha MK, Saha B.

Clin Exp Immunol. 2014 May;176(2):283-90. doi: 10.1111/cei.12264.

PMID:
24387292
[PubMed - indexed for MEDLINE]

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