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Results: 1 to 20 of 116

1.

Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome.

Toscano MG, Anderson P, Muñoz P, Lucena G, Cobo M, Benabdellah K, Gregory PD, Holmes MC, Martin F.

Dis Model Mech. 2013 Mar;6(2):544-54. doi: 10.1242/dmm.010652. Epub 2013 Jan 11.

PMID:
23324327
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.

Prete F, Catucci M, Labrada M, Gobessi S, Castiello MC, Bonomi E, Aiuti A, Vermi W, Cancrini C, Metin A, Hambleton S, Bredius R, Notarangelo LD, van der Burg M, Kalinke U, Villa A, Benvenuti F.

J Exp Med. 2013 Feb 11;210(2):355-74. doi: 10.1084/jem.20120363. Epub 2013 Jan 21.

PMID:
23337808
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes.

Zhang J, Shehabeldin A, da Cruz LA, Butler J, Somani AK, McGavin M, Kozieradzki I, dos Santos AO, Nagy A, Grinstein S, Penninger JM, Siminovitch KA.

J Exp Med. 1999 Nov 1;190(9):1329-42.

PMID:
10544204
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The Wiskott-Aldrich syndrome.

Ochs HD, Thrasher AJ.

J Allergy Clin Immunol. 2006 Apr;117(4):725-38; quiz 739. Review.

PMID:
16630926
[PubMed - indexed for MEDLINE]
5.

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp.

Sato R, Iiizumi S, Kim ES, Honda F, Lee SK, Adachi N, Koyama H, Mizutani S, Morio T.

Int J Hematol. 2012 Mar;95(3):299-310. doi: 10.1007/s12185-012-1013-1. Epub 2012 Feb 5.

PMID:
22311461
[PubMed - indexed for MEDLINE]
6.

Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome.

Facchetti F, Blanzuoli L, Vermi W, Notarangelo LD, Giliani S, Fiorini M, Fasth A, Stewart DM, Nelson DL.

J Pathol. 1998 May;185(1):99-107.

PMID:
9713366
[PubMed - indexed for MEDLINE]
7.

The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions.

Ishihara D, Dovas A, Park H, Isaac BM, Cox D.

PLoS One. 2012;7(1):e30033. doi: 10.1371/journal.pone.0030033. Epub 2012 Jan 18.

PMID:
22279563
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hematopoietic-specific lentiviral vectors circumvent cellular toxicity due to ectopic expression of Wiskott-Aldrich syndrome protein.

Toscano MG, Frecha C, Benabdellah K, Cobo M, Blundell M, Thrasher AJ, García-Olivares E, Molina IJ, Martin F.

Hum Gene Ther. 2008 Feb;19(2):179-97. doi: 10.1089/hum.2007.098.

PMID:
18240968
[PubMed - indexed for MEDLINE]
9.

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function.

Blundell MP, Worth A, Bouma G, Thrasher AJ.

Dis Markers. 2010;29(3-4):157-75. doi: 10.3233/DMA-2010-0735. Review.

PMID:
21178275
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Novel membrane cell projection defects in Wiskott-Aldrich syndrome B cells.

Andreu N, Aran JM, Fillat C.

Int J Mol Med. 2007 Oct;20(4):445-50.

PMID:
17786274
[PubMed - indexed for MEDLINE]
11.

Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.

Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL.

Clin Immunol. 2007 Jul;124(1):41-8. Epub 2007 May 18.

PMID:
17512803
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Retrovirus-mediated WASP gene transfer corrects Wiskott-Aldrich syndrome T-cell dysfunction.

Wada T, Jagadeesh GJ, Nelson DL, Candotti F.

Hum Gene Ther. 2002 Jun 10;13(9):1039-46.

PMID:
12067437
[PubMed - indexed for MEDLINE]
13.

Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.

Taylor MD, Sadhukhan S, Kottangada P, Ramgopal A, Sarkar K, D'Silva S, Selvakumar A, Candotti F, Vyas YM.

Sci Transl Med. 2010 Jun 23;2(37):37ra44. doi: 10.1126/scitranslmed.3000813.

PMID:
20574068
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

WASP and the phenotypic range associated with deficiency.

Notarangelo LD, Notarangelo LD, Ochs HD.

Curr Opin Allergy Clin Immunol. 2005 Dec;5(6):485-90. Review.

PMID:
16264326
[PubMed - indexed for MEDLINE]
15.

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

Charrier S, Stockholm D, Seye K, Opolon P, Taveau M, Gross DA, Bucher-Laurent S, Delenda C, Vainchenker W, Danos O, Galy A.

Gene Ther. 2005 Apr;12(7):597-606.

PMID:
15616597
[PubMed - indexed for MEDLINE]
16.

Development of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome.

Boztug K, Dewey RA, Klein C.

Curr Opin Mol Ther. 2006 Oct;8(5):390-5. Review.

PMID:
17078381
[PubMed - indexed for MEDLINE]
17.

WASP: a key immunological multitasker.

Thrasher AJ, Burns SO.

Nat Rev Immunol. 2010 Mar;10(3):182-92. doi: 10.1038/nri2724. Review.

PMID:
20182458
[PubMed - indexed for MEDLINE]
18.

WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha.

Gallego MD, de la Fuente MA, Anton IM, Snapper S, Fuhlbrigge R, Geha RS.

Int Immunol. 2006 Feb;18(2):221-32. Epub 2005 Sep 1.

PMID:
16141245
[PubMed - indexed for MEDLINE]
Free Article
19.

Expression of Wiskott-Aldrich syndrome protein (WASP) gene during hematopoietic differentiation.

Parolini O, Berardelli S, Riedl E, Bello-Fernandez C, Strobl H, Majdic O, Knapp W.

Blood. 1997 Jul 1;90(1):70-5.

PMID:
9207440
[PubMed - indexed for MEDLINE]
Free Article
20.

WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype.

Imai K, Nonoyama S, Ochs HD.

Curr Opin Allergy Clin Immunol. 2003 Dec;3(6):427-36. Review.

PMID:
14612666
[PubMed - indexed for MEDLINE]

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