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Results: 1 to 20 of 100

1.

Functions of the third intracellular loop of the human melanocortin-3 receptor.

Wang ZQ, Tao YX.

Curr Pharm Des. 2013;19(27):4831-8.

PMID:
23323615
[PubMed - indexed for MEDLINE]
2.

Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction.

Chen M, Aprahamian CJ, Celik A, Georgeson KE, Garvey WT, Harmon CM, Yang Y.

Biochemistry. 2006 Jan 31;45(4):1128-37.

PMID:
16430209
[PubMed - indexed for MEDLINE]
3.

Functions of acidic transmembrane residues in human melanocortin-3 receptor binding and activation.

Wang SX, Fan ZC, Tao YX.

Biochem Pharmacol. 2008 Aug 15;76(4):520-30. doi: 10.1016/j.bcp.2008.05.026. Epub 2008 Jul 9.

PMID:
18614155
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Structural insight into the role of the human melanocortin 3 receptor cysteine residues on receptor function.

Yang Y, Chen M, McPherson D, Mishra V, Harmon CM.

Peptides. 2011 Dec;32(12):2377-83. doi: 10.1016/j.peptides.2011.09.024. Epub 2011 Oct 31.

PMID:
22079958
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.

Frändberg PA, Doufexis M, Kapas S, Chhajlani V.

Biochem Biophys Res Commun. 2001 Mar 9;281(4):851-7.

PMID:
11237737
[PubMed - indexed for MEDLINE]
6.

Novel binding motif of ACTH analogues at the melanocortin receptors.

Yang Y, Hruby VJ, Chen M, Crasto C, Cai M, Harmon CM.

Biochemistry. 2009 Oct 20;48(41):9775-84. doi: 10.1021/bi900634e.

PMID:
19743876
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations.

Yang F, Tao YX.

Biochim Biophys Acta. 2012 Nov;1822(11):1752-61. doi: 10.1016/j.bbadis.2012.07.017. Epub 2012 Aug 3.

PMID:
22884546
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Molecular cloning and pharmacological characterization of porcine melanocortin-3 receptor.

Fan ZC, Sartin JL, Tao YX.

J Endocrinol. 2008 Jan;196(1):139-48. doi: 10.1677/JOE-07-0403.

PMID:
18180325
[PubMed - indexed for MEDLINE]
Free Article
9.

Identification of ligand binding residues in extracellular loops of the melanocortin 1 receptor.

Chhajlani V, Xu X, Blauw J, Sudarshi S.

Biochem Biophys Res Commun. 1996 Feb 15;219(2):521-5.

PMID:
8605020
[PubMed - indexed for MEDLINE]
10.

Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling.

Yang Y, Chen M, Loux TJ, Georgeson KE, Harmon CM.

Biochemistry. 2005 May 10;44(18):6971-9.

PMID:
15865442
[PubMed - indexed for MEDLINE]
11.

Amino acid residues in third intracellular loop of melanocortin 1 receptor are involved in G-protein coupling.

Frändberg PA, Doufexis M, Kapas S, Chhajlani V.

Biochem Mol Biol Int. 1998 Dec;46(5):913-22.

PMID:
9861445
[PubMed - indexed for MEDLINE]
12.

Molecular characterization of human melanocortin-5 receptor ligand-receptor interaction.

Yang Y, Mishra VK, Chen M, Duffee E, Dimmitt R, Harmon CM.

Biochemistry. 2013 Mar 12;52(10):1737-45. doi: 10.1021/bi3013593. Epub 2013 Feb 27.

PMID:
23414113
[PubMed - indexed for MEDLINE]
13.

Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein.

Oosterom J, Garner KM, den Dekker WK, Nijenhuis WA, Gispen WH, Burbach JP, Barsh GS, Adan RA.

J Biol Chem. 2001 Jan 12;276(2):931-6.

PMID:
11024027
[PubMed - indexed for MEDLINE]
Free Article
14.

Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation.

Fleck BA, Ling N, Chen C.

Biochemistry. 2007 Sep 18;46(37):10473-83. Epub 2007 Aug 23.

PMID:
17713970
[PubMed - indexed for MEDLINE]
15.

γ₂-Melanocyte stimulation hormone (γ₂-MSH) truncation studies results in the cautionary note that γ₂-MSH is not selective for the mouse MC3R over the mouse MC5R.

Joseph CG, Yao H, Scott JW, Sorensen NB, Marnane RN, Mountjoy KG, Haskell-Luevano C.

Peptides. 2010 Dec;31(12):2304-13. doi: 10.1016/j.peptides.2010.08.025. Epub 2010 Sep 15.

PMID:
20833220
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor.

Mayorov AV, Cai M, Palmer ES, Dedek MM, Cain JP, Van Scoy AR, Tan B, Vagner J, Trivedi D, Hruby VJ.

J Med Chem. 2008 Jan 24;51(2):187-95. Epub 2007 Dec 19.

PMID:
18088090
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Molecular determinants of ligand binding to the human melanocortin-4 receptor.

Yang YK, Fong TM, Dickinson CJ, Mao C, Li JY, Tota MR, Mosley R, Van Der Ploeg LH, Gantz I.

Biochemistry. 2000 Dec 5;39(48):14900-11.

PMID:
11101306
[PubMed - indexed for MEDLINE]
18.
19.

Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors.

Lee EJ, Lee SH, Jung JW, Lee W, Kim BJ, Park KW, Lim SK, Yoon CJ, Baik JH.

Eur J Biochem. 2001 Feb;268(3):582-91.

PMID:
11168397
[PubMed - indexed for MEDLINE]
Free Article
20.

The third intracellular loop plays a critical role in bitter taste receptor activation.

Pydi SP, Singh N, Upadhyaya J, Bhullar RP, Chelikani P.

Biochim Biophys Acta. 2014 Jan;1838(1 Pt B):231-6. doi: 10.1016/j.bbamem.2013.08.009. Epub 2013 Aug 29.

PMID:
23994601
[PubMed - indexed for MEDLINE]

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