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Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.

Miles RR, Perry W, Haas JV, Mosior MK, N'Cho M, Wang JW, Yu P, Calley J, Yue Y, Carter Q, Han B, Foxworthy P, Kowala MC, Ryan TP, Solenberg PJ, Michael LF.

J Biol Chem. 2013 Mar 1;288(9):6386-96. doi: 10.1074/jbc.M112.410092. Epub 2013 Jan 15.


Rosuvastatin does not affect human apolipoprotein A-I expression in genetically modified mice: a clue to the disputed effect of statins on HDL.

Marchesi M, Parolini C, Caligari S, Gilio D, Manzini S, Busnelli M, Cinquanta P, Camera M, Brambilla M, Sirtori CR, Chiesa G.

Br J Pharmacol. 2011 Nov;164(5):1460-8. doi: 10.1111/j.1476-5381.2011.01429.x.


ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes.

Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R.

J Lipid Res. 2004 Jun;45(6):1122-31. Epub 2004 Mar 1.


Reduced biliary sterol output with no change in total faecal excretion in mice expressing a human apolipoprotein A-I variant.

Parolini C, Caligari S, Gilio D, Manzini S, Busnelli M, Montagnani M, Locatelli M, Diani E, Giavarini F, Caruso D, Roda E, Roda A, Sirtori CR, Chiesa G.

Liver Int. 2012 Oct;32(9):1363-71. doi: 10.1111/j.1478-3231.2012.02855.x. Epub 2012 Jul 29.


Safe and sustained overexpression of functional apolipoprotein A-I/high-density lipoprotein in apolipoprotein A-I-null mice by muscular adeno-associated viral serotype 8 vector gene transfer.

Cimmino G, Chen W, Speidl WS, Giannarelli C, Ibanez B, Fuster V, Hajjar R, Walsh CE, Badimon JJ.

J Cardiovasc Pharmacol. 2009 Nov;54(5):405-11. doi: 10.1097/FJC.0b013e3181bad264.


ApoA-I lipidation in primary mouse hepatocytes. Separate controls for phospholipid and cholesterol transfers.

Zheng H, Kiss RS, Franklin V, Wang MD, Haidar B, Marcel YL.

J Biol Chem. 2005 Jun 3;280(22):21612-21. Epub 2005 Mar 29.


Hepatic high-density lipoprotein secretion regulates the mobilization of cell-surface hepatic lipase.

Chatterjee C, Young EK, Pussegoda KA, Twomey EE, Pandey NR, Sparks DL.

Biochemistry. 2009 Jun 30;48(25):5994-6001. doi: 10.1021/bi802009e.


Effect of experimental nephrosis on hepatic lipoprotein secretion and urinary lipoprotein excretion in rats expressing the human apolipoprotein A-I gene.

Marsh JB, Diffenderfer MR, Fisher EA, Sowden M, Dong M, Paterniti JR, Burkey BF.

J Lipid Res. 1996 May;37(5):1113-24.


Apolipoprotein E gene expression is reduced in apolipoprotein A-I transgenic mice.

Srivastava RA.

Mol Cell Biochem. 2000 Jun;209(1-2):125-9.


Proteolytic degradation and impaired secretion of an apolipoprotein A-I mutant associated with dominantly inherited hypoalphalipoproteinemia.

McManus DC, Scott BR, Franklin V, Sparks DL, Marcel YL.

J Biol Chem. 2001 Jun 15;276(24):21292-302. Epub 2001 Apr 5.


The thienotriazolodiazepine Ro 11-1464 increases plasma apoA-I and promotes reverse cholesterol transport in human apoA-I transgenic mice.

Zanotti I, Maugeais C, Pedrelli M, Gomaraschi M, Salgam P, Calabresi L, Bernini F, Kempen H.

Br J Pharmacol. 2011 Nov;164(6):1642-51. doi: 10.1111/j.1476-5381.2011.01376.x.


Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.

Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE.

J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14.


Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice.

Tietge UJ, Maugeais C, Lund-Katz S, Grass D, deBeer FC, Rader DJ.

Arterioscler Thromb Vasc Biol. 2002 Jul 1;22(7):1213-8.


ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes.

Plump AS, Azrolan N, Odaka H, Wu L, Jiang X, Tall A, Eisenberg S, Breslow JL.

J Lipid Res. 1997 May;38(5):1033-47.


The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1-dependent and -independent pathways.

Kiss RS, McManus DC, Franklin V, Tan WL, McKenzie A, Chimini G, Marcel YL.

J Biol Chem. 2003 Mar 21;278(12):10119-27. Epub 2003 Jan 22.


Low-density lipoprotein apheresis: an evidence-based analysis.

Health Quality Ontario.

Ont Health Technol Assess Ser. 2007;7(5):1-101. Epub 2006 Nov 1.

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