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Items: 1 to 20 of 83

1.

Deciphering the syntax of cytotoxic lymphocyte degranulation.

Lopez JA, Voskoboinik I.

Eur J Immunol. 2013 Jan;43(1):46-9. doi: 10.1002/eji.201243221.

2.

Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.

D'Orlando O, Zhao F, Kasper B, Orinska Z, Müller J, Hermans-Borgmeyer I, Griffiths GM, Zur Stadt U, Bulfone-Paus S.

Eur J Immunol. 2013 Jan;43(1):194-208. doi: 10.1002/eji.201142343. Epub 2012 Dec 12.

3.

Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity.

Arneson LN, Brickshawana A, Segovis CM, Schoon RA, Dick CJ, Leibson PJ.

J Immunol. 2007 Sep 15;179(6):3397-401.

4.

A unique SNARE machinery for exocytosis of cytotoxic granules and platelets granules.

Tang BL.

Mol Membr Biol. 2015;32(4):120-6. doi: 10.3109/09687688.2015.1079934. Review.

PMID:
26508555
5.

The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation.

Dressel R, Elsner L, Novota P, Kanwar N, Fischer von Mollard G.

J Immunol. 2010 Jul 15;185(2):1005-14. doi: 10.4049/jimmunol.1000770. Epub 2010 Jun 11.

6.

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease.

Kögl T, Müller J, Jessen B, Schmitt-Graeff A, Janka G, Ehl S, zur Stadt U, Aichele P.

Blood. 2013 Jan 24;121(4):604-13. doi: 10.1182/blood-2012-07-441139. Epub 2012 Nov 27.

7.

Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules.

Dabrazhynetskaya A, Ma J, Guerreiro-Cacais AO, Arany Z, Rudd E, Henter JI, Karre K, Levitskaya J, Levitsky V.

J Cell Mol Med. 2012 Jan;16(1):129-41. doi: 10.1111/j.1582-4934.2011.01280.x.

8.

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

Côte M, Ménager MM, Burgess A, Mahlaoui N, Picard C, Schaffner C, Al-Manjomi F, Al-Harbi M, Alangari A, Le Deist F, Gennery AR, Prince N, Cariou A, Nitschke P, Blank U, El-Ghazali G, Ménasché G, Latour S, Fischer A, de Saint Basile G.

J Clin Invest. 2009 Dec;119(12):3765-73. doi: 10.1172/JCI40732. Epub 2009 Nov 2.

11.

Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka G, Griffiths G, Ehl S, Hennies HC.

Am J Hum Genet. 2009 Oct;85(4):482-92. doi: 10.1016/j.ajhg.2009.09.005.

13.

Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells.

Zhang S, Ma D, Wang X, Celkan T, Nordenskjöld M, Henter JI, Fadeel B, Zheng C.

Br J Haematol. 2008 Jul;142(3):469-79. doi: 10.1111/j.1365-2141.2008.07191.x. Epub 2008 Jun 11.

PMID:
18547321
14.

Perforin-mediated target-cell death and immune homeostasis.

Voskoboinik I, Smyth MJ, Trapani JA.

Nat Rev Immunol. 2006 Dec;6(12):940-52. Review.

PMID:
17124515
15.

Syntaxin binding mechanism and disease-causing mutations in Munc18-2.

Hackmann Y, Graham SC, Ehl S, Höning S, Lehmberg K, Aricò M, Owen DJ, Griffiths GM.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4482-91. doi: 10.1073/pnas.1313474110. Epub 2013 Nov 5.

16.

Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes.

Bhat SS, Friedmann KS, Knörck A, Hoxha C, Leidinger P, Backes C, Meese E, Keller A, Rettig J, Hoth M, Qu B, Schwarz EC.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1653-64. doi: 10.1016/j.bbamcr.2016.04.014. Epub 2016 Apr 17.

PMID:
27094127
17.

Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes.

Halimani M, Pattu V, Marshall MR, Chang HF, Matti U, Jung M, Becherer U, Krause E, Hoth M, Schwarz EC, Rettig J.

Eur J Immunol. 2014 Feb;44(2):573-84. doi: 10.1002/eji.201344011. Epub 2013 Dec 16.

18.

Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils.

Brochetta C, Vita F, Tiwari N, Scandiuzzi L, Soranzo MR, Guérin-Marchand C, Zabucchi G, Blank U.

Biochim Biophys Acta. 2008 Oct;1783(10):1781-91. doi: 10.1016/j.bbamcr.2008.05.023. Epub 2008 Jun 6.

19.

Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis.

Rudd E, Bryceson YT, Zheng C, Edner J, Wood SM, Ramme K, Gavhed S, Gürgey A, Hellebostad M, Bechensteen AG, Ljunggren HG, Fadeel B, Nordenskjöld M, Henter JI.

J Med Genet. 2008 Mar;45(3):134-41. Epub 2007 Nov 9.

PMID:
17993578
20.

Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.

Kojima Y, Kawasaki-Koyanagi A, Sueyoshi N, Kanai A, Yagita H, Okumura K.

Biochem Biophys Res Commun. 2002 Aug 16;296(2):328-36.

PMID:
12163021
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