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Items: 1 to 20 of 91

1.

Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function.

Collins CB, Aherne CM, Yeckes A, Pound K, Eltzschig HK, Jedlicka P, de Zoeten EF.

Mucosal Immunol. 2013 Sep;6(5):960-71. doi: 10.1038/mi.2012.134. Epub 2013 Jan 16.

2.

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.

Ambade A, Catalano D, Lim A, Mandrekar P.

Hepatology. 2012 May;55(5):1585-95. doi: 10.1002/hep.24802. Epub 2012 Mar 18.

3.

Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner.

Chai RC, Kouspou MM, Lang BJ, Nguyen CH, van der Kraan AG, Vieusseux JL, Lim RC, Gillespie MT, Benjamin IJ, Quinn JM, Price JT.

J Biol Chem. 2014 May 9;289(19):13602-14. doi: 10.1074/jbc.M113.530626. Epub 2014 Apr 1.

4.

Targeted inhibition of heat shock protein 90 suppresses tumor necrosis factor-α and ameliorates murine intestinal inflammation.

Collins CB, Strassheim D, Aherne CM, Yeckes AR, Jedlicka P, de Zoeten EF.

Inflamm Bowel Dis. 2014 Apr;20(4):685-94. doi: 10.1097/01.MIB.0000442839.28664.75.

5.

The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.

Dello Russo C, Polak PE, Mercado PR, Spagnolo A, Sharp A, Murphy P, Kamal A, Burrows FJ, Fritz LC, Feinstein DL.

J Neurochem. 2006 Dec;99(5):1351-62. Epub 2006 Oct 25.

6.

HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes.

Ali A, Bharadwaj S, O'Carroll R, Ovsenek N.

Mol Cell Biol. 1998 Sep;18(9):4949-60.

7.

Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3.

Song S, Kole S, Precht P, Pazin MJ, Bernier M.

Int J Biochem Cell Biol. 2010 Nov;42(11):1856-63. doi: 10.1016/j.biocel.2010.07.021. Epub 2010 Aug 6.

8.

Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis.

Madrigal-Matute J, López-Franco O, Blanco-Colio LM, Muñoz-García B, Ramos-Mozo P, Ortega L, Egido J, Martín-Ventura JL.

Cardiovasc Res. 2010 May 1;86(2):330-7. doi: 10.1093/cvr/cvq046. Epub 2010 Feb 12.

9.

Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis.

Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T.

J Biol Chem. 2007 Aug 10;282(32):23240-52. Epub 2007 Jun 7.

10.

Characterizing the role of Hsp90 in production of heat shock proteins in motor neurons reveals a suppressive effect of wild-type Hsf1.

Taylor DM, Tradewell ML, Minotti S, Durham HD.

Cell Stress Chaperones. 2007 Summer;12(2):151-62.

11.

Heat shock transcription factor 1 attenuates TNFα-induced cardiomyocyte death through suppression of NFκB pathway.

Wu L, Hu C, Huang M, Jiang M, Lu L, Tang J.

Gene. 2013 Sep 15;527(1):89-94. doi: 10.1016/j.gene.2013.05.024. Epub 2013 Jun 12.

PMID:
23769970
12.

Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses.

Tukaj S, Tiburzy B, Manz R, de Castro Marques A, Orosz A, Ludwig RJ, Zillikens D, Kasperkiewicz M.

Exp Dermatol. 2014 Aug;23(8):585-90. doi: 10.1111/exd.12476.

PMID:
24961936
13.
14.

Possible involvement of HSP90-HSF1 multichaperone complex in impairment of HSP72 induction in the failing heart following myocardial infarction in rats.

Marunouchi T, Araki M, Murata M, Takagi N, Tanonaka K.

J Pharmacol Sci. 2013;123(4):336-46. Epub 2013 Nov 27.

15.

Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis.

Batulan Z, Taylor DM, Aarons RJ, Minotti S, Doroudchi MM, Nalbantoglu J, Durham HD.

Neurobiol Dis. 2006 Nov;24(2):213-25. Epub 2006 Sep 6.

PMID:
16950627
16.

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer.

Ruckova E, Muller P, Nenutil R, Vojtesek B.

Cell Mol Biol Lett. 2012 Sep;17(3):446-58. doi: 10.2478/s11658-012-0021-8. Epub 2012 Jun 5.

PMID:
22669480
17.

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.

Shen HY, He JC, Wang Y, Huang QY, Chen JF.

J Biol Chem. 2005 Dec 2;280(48):39962-9. Epub 2005 Oct 6.

18.

Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice.

Lee JH, Gao J, Kosinski PA, Elliman SJ, Hughes TE, Gromada J, Kemp DM.

Biochem Biophys Res Commun. 2013 Jan 18;430(3):1109-13. doi: 10.1016/j.bbrc.2012.12.029. Epub 2012 Dec 19.

PMID:
23261432
19.

Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment.

Chen Y, Wang B, Liu D, Li JJ, Xue Y, Sakata K, Zhu LQ, Heldt SA, Xu H, Liao FF.

J Neurosci. 2014 Feb 12;34(7):2464-70. doi: 10.1523/JNEUROSCI.0151-13.2014.

20.
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