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Results: 1 to 20 of 109

1.

Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells.

Kelly C, Canning P, Buchanan PJ, Williams MT, Brown V, Gruenert DC, Elborn JS, Ennis M, Schock BC.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L371-82. doi: 10.1152/ajplung.00372.2011. Epub 2013 Jan 11.

PMID:
23316065
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells.

John G, Yildirim AO, Rubin BK, Gruenert DC, Henke MO.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):424-31. doi: 10.1165/rcmb.2008-0408OC. Epub 2009 Jun 5.

PMID:
19502387
[PubMed - indexed for MEDLINE]
3.

TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.

Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S, O'neill SJ, McElvaney NG.

J Immunol. 2005 Feb 1;174(3):1638-46.

PMID:
15661927
[PubMed - indexed for MEDLINE]
Free Article
4.

Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4.

Wang Y, Chen T, Han C, He D, Liu H, An H, Cai Z, Cao X.

Blood. 2007 Aug 1;110(3):962-71. Epub 2007 Mar 29.

PMID:
17395780
[PubMed - indexed for MEDLINE]
Free Article
5.

Expression of the nuclear factor-κB inhibitor A20 is altered in the cystic fibrosis epithelium.

Kelly C, Williams MT, Mitchell K, Elborn JS, Ennis M, Schock BC.

Eur Respir J. 2013 Jun;41(6):1315-23. doi: 10.1183/09031936.00032412. Epub 2012 Sep 27.

PMID:
23018911
[PubMed - indexed for MEDLINE]
6.

Reduced surface toll-like receptor-4 expression and absent interferon-γ-inducible protein-10 induction in cystic fibrosis airway cells.

John G, Chillappagari S, Rubin BK, Gruenert DC, Henke MO.

Exp Lung Res. 2011 Aug;37(6):319-26. doi: 10.3109/01902148.2011.569968. Epub 2011 Jun 7.

PMID:
21649525
[PubMed - indexed for MEDLINE]
7.

Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells.

Shuto T, Furuta T, Oba M, Xu H, Li JD, Cheung J, Gruenert DC, Uehara A, Suico MA, Okiyoneda T, Kai H.

FASEB J. 2006 Apr;20(6):782-4. Epub 2006 Feb 14.

PMID:
16478769
[PubMed - indexed for MEDLINE]
Free Article
8.

Toll-like receptors in normal and cystic fibrosis airway epithelial cells.

Muir A, Soong G, Sokol S, Reddy B, Gomez MI, Van Heeckeren A, Prince A.

Am J Respir Cell Mol Biol. 2004 Jun;30(6):777-83. Epub 2003 Dec 4.

PMID:
14656745
[PubMed - indexed for MEDLINE]
9.

Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis.

Bruscia EM, Zhang PX, Satoh A, Caputo C, Medzhitov R, Shenoy A, Egan ME, Krause DS.

J Immunol. 2011 Jun 15;186(12):6990-8. doi: 10.4049/jimmunol.1100396. Epub 2011 May 18.

PMID:
21593379
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis.

Hauber HP, Tulic MK, Tsicopoulos A, Wallaert B, Olivenstein R, Daigneault P, Hamid Q.

Can Respir J. 2005 Jan-Feb;12(1):13-8.

PMID:
15776129
[PubMed - indexed for MEDLINE]
11.

Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells.

Parker D, Cohen TS, Alhede M, Harfenist BS, Martin FJ, Prince A.

Am J Respir Cell Mol Biol. 2012 Jan;46(1):6-13. doi: 10.1165/rcmb.2011-0080OC.

PMID:
21778412
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Synergism between interleukin (IL)-17 and Toll-like receptor 2 and 4 signals to induce IL-8 expression in cystic fibrosis airway epithelial cells.

Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H.

J Pharmacol Sci. 2012;118(4):512-20. Epub 2012 Mar 29.

PMID:
22466961
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation.

Schroeder TH, Lee MM, Yacono PW, Cannon CL, Gerçeker AA, Golan DE, Pier GB.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6907-12. Epub 2002 May 7.

PMID:
11997458
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Pseudomonas aeruginosa-induced apoptosis in airway epithelial cells is mediated by gap junctional communication in a JNK-dependent manner.

Losa D, Köhler T, Bellec J, Dudez T, Crespin S, Bacchetta M, Boulanger P, Hong SS, Morel S, Nguyen TH, van Delden C, Chanson M.

J Immunol. 2014 May 15;192(10):4804-12. doi: 10.4049/jimmunol.1301294. Epub 2014 Apr 14.

PMID:
24733844
[PubMed - indexed for MEDLINE]
15.

IL-17 primes airway epithelial cells lacking functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) to increase NOD1 responses.

Roussel L, Rousseau S.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):505-9. doi: 10.1016/j.bbrc.2009.11.088. Epub 2009 Nov 20.

PMID:
19931506
[PubMed - indexed for MEDLINE]
16.

TLR expression on neutrophils at the pulmonary site of infection: TLR1/TLR2-mediated up-regulation of TLR5 expression in cystic fibrosis lung disease.

Koller B, Kappler M, Latzin P, Gaggar A, Schreiner M, Takyar S, Kormann M, Kabesch M, Roos D, Griese M, Hartl D.

J Immunol. 2008 Aug 15;181(4):2753-63.

PMID:
18684966
[PubMed - indexed for MEDLINE]
Free Article
17.

Innate immune response in CF airway epithelia: hyperinflammatory?

Machen TE.

Am J Physiol Cell Physiol. 2006 Aug;291(2):C218-30. Review.

PMID:
16825601
[PubMed - indexed for MEDLINE]
Free Article
18.

Reduced expression of Tis7/IFRD1 protein in murine and human cystic fibrosis airway epithelial cell models homozygous for the F508del-CFTR mutation.

Blanchard E, Marie S, Riffault L, Bonora M, Tabary O, Clement A, Jacquot J.

Biochem Biophys Res Commun. 2011 Aug 5;411(3):471-6. doi: 10.1016/j.bbrc.2011.06.104. Epub 2011 Jun 24.

PMID:
21723850
[PubMed - indexed for MEDLINE]
19.

Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence.

Scheid P, Kempster L, Griesenbach U, Davies JC, Dewar A, Weber PP, Colledge WH, Evans MJ, Geddes DM, Alton EW.

Eur Respir J. 2001 Jan;17(1):27-35.

PMID:
11307750
[PubMed - indexed for MEDLINE]
Free Article
20.

Differential regulation of inflammation by inflammatory mediators in cystic fibrosis lung epithelial cells.

Tsuchiya M, Kumar P, Bhattacharyya S, Chattoraj S, Srivastava M, Pollard HB, Biswas R.

J Interferon Cytokine Res. 2013 Mar;33(3):121-9. doi: 10.1089/jir.2012.0074. Epub 2013 Jan 4.

PMID:
23289731
[PubMed - indexed for MEDLINE]

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