Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 125

1.

The products of the reaction between 6-amine-1,3-dimethyl uracil and bis-chalcones induce cytotoxicity with massive vacuolation in HeLa cervical cancer cell line.

Solano JD, González-Sánchez I, Cerbón MA, Guzmán Á, Martínez-Urbina MA, Vilchis-Reyes MA, Martínez-Zuñiga EC, Alvarado C, Quintero A, Díaz E.

Eur J Med Chem. 2013 Feb;60:350-9. doi: 10.1016/j.ejmech.2012.12.021. Epub 2012 Dec 17.

PMID:
23314048
[PubMed - indexed for MEDLINE]
2.

Synthesis and biological evaluation of 2',5'-dimethoxychalcone derivatives as microtubule-targeted anticancer agents.

Tu HY, Huang AM, Hour TC, Yang SC, Pu YS, Lin CN.

Bioorg Med Chem. 2010 Mar 15;18(6):2089-98. doi: 10.1016/j.bmc.2010.02.012. Epub 2010 Feb 12.

PMID:
20199865
[PubMed - indexed for MEDLINE]
3.

Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: structure-activity relationship.

Shenvi S, Kumar K, Hatti KS, Rijesh K, Diwakar L, Reddy GC.

Eur J Med Chem. 2013 Apr;62:435-42. doi: 10.1016/j.ejmech.2013.01.018. Epub 2013 Jan 23.

PMID:
23395966
[PubMed - indexed for MEDLINE]
4.

Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.

Boumendjel A, Boccard J, Carrupt PA, Nicolle E, Blanc M, Geze A, Choisnard L, Wouessidjewe D, Matera EL, Dumontet C.

J Med Chem. 2008 Apr 10;51(7):2307-10. doi: 10.1021/jm0708331. Epub 2008 Feb 23.

PMID:
18293907
[PubMed - indexed for MEDLINE]
5.

Synthesis and biological evaluation of indolyl chalcones as antitumor agents.

Kumar D, Kumar NM, Akamatsu K, Kusaka E, Harada H, Ito T.

Bioorg Med Chem Lett. 2010 Jul 1;20(13):3916-9. doi: 10.1016/j.bmcl.2010.05.016. Epub 2010 May 13.

PMID:
20627724
[PubMed - indexed for MEDLINE]
6.

Apoptotic events induced by synthetic naphthylchalcones in human acute leukemia cell lines.

Maioral MF, Gaspar PC, Rosa Souza GR, Mascarello A, Chiaradia LD, Licínio MA, Moraes AC, Yunes RA, Nunes RJ, Santos-Silva MC.

Biochimie. 2013 Apr;95(4):866-74. doi: 10.1016/j.biochi.2012.12.001. Epub 2012 Dec 17.

PMID:
23257665
[PubMed - indexed for MEDLINE]
Free Article
7.

Synthesis of novel 1H-1,2,3-triazole tethered C-5 substituted uracil-isatin conjugates and their cytotoxic evaluation.

Kumar K, Sagar S, Esau L, Kaur M, Kumar V.

Eur J Med Chem. 2012 Dec;58:153-9. doi: 10.1016/j.ejmech.2012.10.008. Epub 2012 Oct 12.

PMID:
23124212
[PubMed - indexed for MEDLINE]
8.

Methoxy- and fluoro-chalcone derivatives arrest cell cycle progression and induce apoptosis in human melanoma cell A375.

Henmi K, Hiwatashi Y, Hikita E, Toyama N, Hirano T.

Biol Pharm Bull. 2009 Jun;32(6):1109-13.

PMID:
19483325
[PubMed - indexed for MEDLINE]
Free Article
9.

β-Ionone derived chalcones as potent antiproliferative agents.

Sharma V, Chaudhary A, Arora S, Saxena AK, Ishar MP.

Eur J Med Chem. 2013 Nov;69:310-5. doi: 10.1016/j.ejmech.2013.08.017. Epub 2013 Aug 19.

PMID:
24056146
[PubMed - indexed for MEDLINE]
10.

Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl)amino]chalcones and hydrazine as potential antitumor and antimalarial agents.

Insuasty B, Montoya A, Becerra D, Quiroga J, Abonia R, Robledo S, Vélez ID, Upegui Y, Nogueras M, Cobo J.

Eur J Med Chem. 2013 Sep;67:252-62. doi: 10.1016/j.ejmech.2013.06.049. Epub 2013 Jul 2.

PMID:
23871905
[PubMed - indexed for MEDLINE]
11.

Synthesis of methoxy-substituted chalcones and in vitro evaluation of their anticancer potential.

Ethiraj KR, Aranjani JM, Khan FR.

Chem Biol Drug Des. 2013 Dec;82(6):732-42. doi: 10.1111/cbdd.12184.

PMID:
23834620
[PubMed - indexed for MEDLINE]
12.

Design, synthesis, and biological evaluation of thiophene analogues of chalcones.

Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.

Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15.

PMID:
18440234
[PubMed - indexed for MEDLINE]
13.

α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells.

Bazzaro M, Anchoori RK, Mudiam MK, Issaenko O, Kumar S, Karanam B, Lin Z, Isaksson Vogel R, Gavioli R, Destro F, Ferretti V, Roden RB, Khan SR.

J Med Chem. 2011 Jan 27;54(2):449-56. doi: 10.1021/jm100589p. Epub 2010 Dec 27.

PMID:
21186794
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Synthesis, structure activity relationship and mode of action of 3-substitutedphenyl-1-(2,2,8,8-tetramethyl-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-6-yl)-propenones as novel anticancer agents in human leukaemia HL-60 cells.

Murthy YL, Suhasini KP, Pathania AS, Bhushan S, Nagendra Sastry Y.

Eur J Med Chem. 2013 Apr;62:545-55. doi: 10.1016/j.ejmech.2013.01.027. Epub 2013 Jan 29.

PMID:
23419739
[PubMed - indexed for MEDLINE]
15.

Solid-phase synthesis of 2'-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines.

Neves MP, Cravo S, Lima RT, Vasconcelos MH, Nascimento MS, Silva AM, Pinto M, Cidade H, Corrêa AG.

Bioorg Med Chem. 2012 Jan 1;20(1):25-33. doi: 10.1016/j.bmc.2011.11.042. Epub 2011 Nov 30.

PMID:
22177409
[PubMed - indexed for MEDLINE]
16.

Synthesis, structure, and in vitro antitumor activity of some glycoside derivatives of ferrocenyl-chalcones and ferrocenyl-pyrazolines.

Zsoldos-Mády V, Csámpai A, Szabó R, Mészáros-Alapi E, Pásztor J, Hudecz F, Sohár P.

ChemMedChem. 2006 Oct;1(10):1119-25.

PMID:
16944543
[PubMed - indexed for MEDLINE]
17.

Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through induction of apoptosis and autophagy.

Wang XJ, Chu NY, Wang QH, Liu C, Jiang CG, Wang XY, Ikejima T, Cheng MS.

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297-300. doi: 10.1016/j.bmcl.2012.06.102. Epub 2012 Jul 7.

PMID:
22959518
[PubMed - indexed for MEDLINE]
18.

Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation.

Mielcke TR, Mascarello A, Filippi-Chiela E, Zanin RF, Lenz G, Leal PC, Chiaradia LD, Yunes RA, Nunes RJ, Battastini AM, Morrone FB, Campos MM.

Eur J Med Chem. 2012 Feb;48:255-64. doi: 10.1016/j.ejmech.2011.12.023. Epub 2011 Dec 22. Erratum in: Eur J Med Chem. 2012 May;51(1):300. Chirardia, Louise D [corrected to Chiaradia, Louise Domeneghini].

PMID:
22209415
[PubMed - indexed for MEDLINE]
19.

2,4-Dihydroxychalcone derivatives as novel potent cell division cycle 25B phosphatase inhibitors and protein tyrosine phosphatase 1B inhibitors.

Xie C, Sun Y, Pan CY, Tang LM, Guan LP.

Pharmazie. 2014 Apr;69(4):257-62.

PMID:
24791588
[PubMed - indexed for MEDLINE]
20.

Synthetic polyamines activating autophagy: effects on cancer cell death.

Minarini A, Zini M, Milelli A, Tumiatti V, Marchetti C, Nicolini B, Falconi M, Farruggia G, Cappadone C, Stefanelli C.

Eur J Med Chem. 2013 Sep;67:359-66. doi: 10.1016/j.ejmech.2013.06.044. Epub 2013 Jul 1.

PMID:
23887056
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk