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Results: 1 to 20 of 108

1.

FXR-dependent and -independent interaction of glucocorticoids with the regulatory pathways involved in the control of bile acid handling by the liver.

Rosales R, Romero MR, Vaquero J, Monte MJ, Requena P, Martinez-Augustin O, Sanchez de Medina F, Marin JJ.

Biochem Pharmacol. 2013 Mar 15;85(6):829-38. doi: 10.1016/j.bcp.2013.01.001. Epub 2013 Jan 10.

PMID:
23313557
[PubMed - indexed for MEDLINE]
2.

Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.

Chen W, Owsley E, Yang Y, Stroup D, Chiang JY.

J Lipid Res. 2001 Sep;42(9):1402-12.

PMID:
11518759
[PubMed - indexed for MEDLINE]
Free Article
3.

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.

Yu J, Lo JL, Huang L, Zhao A, Metzger E, Adams A, Meinke PT, Wright SD, Cui J.

J Biol Chem. 2002 Aug 30;277(35):31441-7. Epub 2002 Jun 6.

PMID:
12052824
[PubMed - indexed for MEDLINE]
Free Article
4.

Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.

Vaquero J, Monte MJ, Dominguez M, Muntané J, Marin JJ.

Biochem Pharmacol. 2013 Oct 1;86(7):926-39. doi: 10.1016/j.bcp.2013.07.022. Epub 2013 Aug 6.

PMID:
23928191
[PubMed - indexed for MEDLINE]
5.

Bile salt excretory pump: biology and pathobiology.

Suchy FJ, Ananthanarayanan M.

J Pediatr Gastroenterol Nutr. 2006 Jul;43 Suppl 1:S10-6. Review.

PMID:
16819395
[PubMed - indexed for MEDLINE]
6.

Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.

Hoeke MO, Plass JR, Heegsma J, Geuken M, van Rijsbergen D, Baller JF, Kuipers F, Moshage H, Jansen PL, Faber KN.

Hepatology. 2009 Jan;49(1):151-9. doi: 10.1002/hep.22661.

PMID:
19111018
[PubMed - indexed for MEDLINE]
7.

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ.

J Biol Chem. 2001 Aug 3;276(31):28857-65. Epub 2001 May 31.

PMID:
11387316
[PubMed - indexed for MEDLINE]
Free Article
8.

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp.

Denson LA, Sturm E, Echevarria W, Zimmerman TL, Makishima M, Mangelsdorf DJ, Karpen SJ.

Gastroenterology. 2001 Jul;121(1):140-7.

PMID:
11438503
[PubMed - indexed for MEDLINE]
9.

The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonism.

Deng R, Yang D, Radke A, Yang J, Yan B.

J Pharmacol Exp Ther. 2007 Mar;320(3):1153-62. Epub 2006 Nov 29.

PMID:
17135343
[PubMed - indexed for MEDLINE]
Free Article
10.

Farnesoid X receptor regulates bile acid-amino acid conjugation.

Pircher PC, Kitto JL, Petrowski ML, Tangirala RK, Bischoff ED, Schulman IG, Westin SK.

J Biol Chem. 2003 Jul 25;278(30):27703-11. Epub 2003 May 16.

PMID:
12754200
[PubMed - indexed for MEDLINE]
Free Article
11.

Changes in the expression of genes related to bile acid synthesis and transport by the rat liver during hepatocarcinogenesis.

Monte MJ, Fernandez-Tagarro M, Macias RI, Jimenez F, Gonzalez-San Martin F, Marin JJ.

Clin Sci (Lond). 2005 Aug;109(2):199-207.

PMID:
15853769
[PubMed - indexed for MEDLINE]
Free Article
12.

Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.

Martínez-Fernández P, Hierro L, Jara P, Alvarez L.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1119-29. doi: 10.1152/ajpgi.90371.2008. Epub 2009 Feb 19.

PMID:
19228886
[PubMed - indexed for MEDLINE]
Free Article
13.

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD.

J Biol Chem. 2001 Oct 19;276(42):39411-8. Epub 2001 Aug 16.

PMID:
11509573
[PubMed - indexed for MEDLINE]
Free Article
14.

Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.

Herraez E, Gonzalez-Sanchez E, Vaquero J, Romero MR, Serrano MA, Marin JJ, Briz O.

Mol Pharm. 2012 Sep 4;9(9):2565-76. doi: 10.1021/mp300178a. Epub 2012 Aug 1.

PMID:
22800197
[PubMed - indexed for MEDLINE]
15.

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.

Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM, Tontonoz P, Kliewer S, Willson TM, Edwards PA.

J Biol Chem. 2002 Jan 25;277(4):2908-15. Epub 2001 Nov 12.

PMID:
11706036
[PubMed - indexed for MEDLINE]
Free Article
16.

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.

Cui J, Huang L, Zhao A, Lew JL, Yu J, Sahoo S, Meinke PT, Royo I, Pelaez F, Wright SD.

J Biol Chem. 2003 Mar 21;278(12):10214-20. Epub 2003 Jan 13.

PMID:
12525500
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.

Zollner G, Wagner M, Fickert P, Geier A, Fuchsbichler A, Silbert D, Gumhold J, Zatloukal K, Kaser A, Tilg H, Denk H, Trauner M.

Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G798-805. Epub 2005 Jul 7.

PMID:
16002565
[PubMed - indexed for MEDLINE]
Free Article
18.

Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice.

Cui JY, Aleksunes LM, Tanaka Y, Fu ZD, Guo Y, Guo GL, Lu H, Zhong XB, Klaassen CD.

Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G979-96. doi: 10.1152/ajpgi.00370.2011. Epub 2012 Jan 19.

PMID:
22268101
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.

Ananthanarayanan M, Li Y, Surapureddi S, Balasubramaniyan N, Ahn J, Goldstein JA, Suchy FJ.

Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G771-81. doi: 10.1152/ajpgi.00499.2010. Epub 2011 Feb 17.

PMID:
21330447
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids.

Frankenberg T, Rao A, Chen F, Haywood J, Shneider BL, Dawson PA.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G912-22. Epub 2005 Dec 15.

PMID:
16357058
[PubMed - indexed for MEDLINE]
Free Article

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