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Results: 1 to 20 of 145

1.

Synthesis, biological evaluation, 3D-QSAR studies of novel aryl-2H-pyrazole derivatives as telomerase inhibitors.

Luo Y, Zhang S, Qiu KM, Liu ZJ, Yang YS, Fu J, Zhong WQ, Zhu HL.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):1091-5. doi: 10.1016/j.bmcl.2012.12.010. Epub 2012 Dec 20.

PMID:
23312949
[PubMed - indexed for MEDLINE]
2.

Synthesis and molecular docking study of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential antitumor agents.

Liu XH, Liu HF, Chen J, Yang Y, Song BA, Bai LS, Liu JX, Zhu HL, Qi XB.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5705-8. doi: 10.1016/j.bmcl.2010.08.017. Epub 2010 Aug 10.

PMID:
20800480
[PubMed - indexed for MEDLINE]
3.

Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents.

Zhang XM, Qiu M, Sun J, Zhang YB, Yang YS, Wang XL, Tang JF, Zhu HL.

Bioorg Med Chem. 2011 Nov 1;19(21):6518-24. doi: 10.1016/j.bmc.2011.08.013. Epub 2011 Aug 16.

PMID:
21962523
[PubMed - indexed for MEDLINE]
4.

Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents.

Liu XH, Ruan BF, Liu JX, Song BA, Jing LH, Li J, Yang Y, Zhu HL, Qi XB.

Bioorg Med Chem Lett. 2011 May 15;21(10):2916-20. doi: 10.1016/j.bmcl.2011.03.066. Epub 2011 Mar 23.

PMID:
21486698
[PubMed - indexed for MEDLINE]
5.

Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors.

Zhang YB, Wang XL, Liu W, Yang YS, Tang JF, Zhu HL.

Bioorg Med Chem. 2012 Nov 1;20(21):6356-65. doi: 10.1016/j.bmc.2012.08.059. Epub 2012 Sep 11.

PMID:
23018096
[PubMed - indexed for MEDLINE]
6.

Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents.

Huang XF, Lu X, Zhang Y, Song GQ, He QL, Li QS, Yang XH, Wei Y, Zhu HL.

Bioorg Med Chem. 2012 Aug 15;20(16):4895-900. doi: 10.1016/j.bmc.2012.06.056. Epub 2012 Jul 10.

PMID:
22819191
[PubMed - indexed for MEDLINE]
7.

Synthesis, biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3,4-oxadiazole moiety as potential antitumor agents.

Zheng QZ, Zhang XM, Xu Y, Cheng K, Jiao QC, Zhu HL.

Bioorg Med Chem. 2010 Nov 15;18(22):7836-41. doi: 10.1016/j.bmc.2010.09.051. Epub 2010 Sep 25.

PMID:
20947362
[PubMed - indexed for MEDLINE]
8.

Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.

Liu JJ, Zhang H, Sun J, Wang ZC, Yang YS, Li DD, Zhang F, Gong HB, Zhu HL.

Bioorg Med Chem. 2012 Oct 15;20(20):6089-96. doi: 10.1016/j.bmc.2012.08.020. Epub 2012 Aug 25.

PMID:
22985957
[PubMed - indexed for MEDLINE]
9.

Identification of novel 3,5-diarylpyrazoline derivatives containing salicylamide moiety as potential anti-melanoma agents.

Li QS, Lv XH, Zhang YB, Dong JJ, Zhou WP, Yang Y, Zhu HL.

Bioorg Med Chem Lett. 2012 Nov 1;22(21):6596-601. doi: 10.1016/j.bmcl.2012.09.004. Epub 2012 Sep 10.

PMID:
23025996
[PubMed - indexed for MEDLINE]
10.

Novel 3-(2-(3-methyl-5-substituted-phenyl-4,5-dihydropyrazol-1-yl)-2-oxoethoxy)-2-substituted-phenyl-4H-chromen-4-one: synthesis and anticancer activity.

Liu XH, Li J, Wu FR, Song BA, Bhadury PS, Shi L.

Med Chem. 2011 Nov;7(6):605-10.

PMID:
22313300
[PubMed - indexed for MEDLINE]
11.

Synthesis and biological evaluation of pyrazole derivatives containing thiourea skeleton as anticancer agents.

Lv PC, Li HQ, Sun J, Zhou Y, Zhu HL.

Bioorg Med Chem. 2010 Jul 1;18(13):4606-14. doi: 10.1016/j.bmc.2010.05.034. Epub 2010 May 20.

PMID:
20627597
[PubMed - indexed for MEDLINE]
12.

Synthesis, molecular modeling and biological evaluation of 2-aminomethyl-5-(quinolin-2-yl)-1,3,4-oxadiazole-2(3H)-thione quinolone derivatives as novel anticancer agent.

Sun J, Zhu H, Yang ZM, Zhu HL.

Eur J Med Chem. 2013 Feb;60:23-8. doi: 10.1016/j.ejmech.2012.11.039. Epub 2012 Dec 4.

PMID:
23279864
[PubMed - indexed for MEDLINE]
13.

Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivatives.

Lee CC, Huang KF, Lin PY, Huang FC, Chen CL, Chen TC, Guh JH, Lin JJ, Huang HS.

Eur J Med Chem. 2012 Jan;47(1):323-36. doi: 10.1016/j.ejmech.2011.10.059. Epub 2011 Nov 7.

PMID:
22100139
[PubMed - indexed for MEDLINE]
14.

Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives containing benzodioxole as potential anticancer agents.

Wang HH, Qiu KM, Cui HE, Yang YS, Yin-Luo, Xing M, Qiu XY, Bai LF, Zhu HL.

Bioorg Med Chem. 2013 Jan 15;21(2):448-55. doi: 10.1016/j.bmc.2012.11.020. Epub 2012 Nov 24.

PMID:
23245802
[PubMed - indexed for MEDLINE]
15.

Design, modification and 3D QSAR studies of novel 2,3-dihydrobenzo[b][1,4]dioxin-containing 4,5-dihydro-1H-pyrazole derivatives as inhibitors of B-Raf kinase.

Yang YS, Li QS, Sun S, Zhang YB, Wang XL, Zhang F, Tang JF, Zhu HL.

Bioorg Med Chem. 2012 Oct 15;20(20):6048-58. doi: 10.1016/j.bmc.2012.08.043. Epub 2012 Aug 30.

PMID:
22985962
[PubMed - indexed for MEDLINE]
16.

Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors.

Li CY, Li QS, Yan L, Sun XG, Wei R, Gong HB, Zhu HL.

Bioorg Med Chem. 2012 Jun 15;20(12):3746-55. doi: 10.1016/j.bmc.2012.04.047. Epub 2012 Apr 28.

PMID:
22583669
[PubMed - indexed for MEDLINE]
17.

Design, modification and 3D QSAR studies of novel naphthalin-containing pyrazoline derivatives with/without thiourea skeleton as anticancer agents.

Yang W, Hu Y, Yang YS, Zhang F, Zhang YB, Wang XL, Tang JF, Zhong WQ, Zhu HL.

Bioorg Med Chem. 2013 Mar 1;21(5):1050-63. doi: 10.1016/j.bmc.2013.01.013. Epub 2013 Jan 16.

PMID:
23391364
[PubMed - indexed for MEDLINE]
18.

Synthesis and biological validation of novel pyrazole derivatives with anticancer activity guided by 3D-QSAR analysis.

Vujasinović I, Paravić-Radičević A, Mlinarić-Majerski K, Brajša K, Bertoša B.

Bioorg Med Chem. 2012 Mar 15;20(6):2101-10. doi: 10.1016/j.bmc.2012.01.032. Epub 2012 Jan 28.

PMID:
22341245
[PubMed - indexed for MEDLINE]
19.

Synthesis and biological evaluation of new phenothiazine derivatives bearing a pyrazole unit as protein farnesyltransferase inhibitors.

Baciu-Atudosie L, Ghinet A, Farce A, Dubois J, Belei D, Bîcu E.

Bioorg Med Chem Lett. 2012 Nov 15;22(22):6896-902. doi: 10.1016/j.bmcl.2012.09.030. Epub 2012 Sep 17.

PMID:
23036952
[PubMed - indexed for MEDLINE]
20.

Design and synthesis of novel 2-methyl-4,5-substitutedbenzo[f]-3,3a,4,5-tetrahydro-pyrazolo[1,5-d][1,4]oxazepin-8(7H)-one derivatives as telomerase inhibitors.

Liu XH, Jia YM, Song BA, Pang ZX, Yang S.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):720-3. doi: 10.1016/j.bmcl.2012.11.101. Epub 2012 Dec 3.

PMID:
23265905
[PubMed - indexed for MEDLINE]

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