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Items: 1 to 20 of 103


Thioredoxin-like protein 2 is overexpressed in colon cancer and promotes cancer cell metastasis by interaction with ran.

Lu Y, Zhao X, Li K, Luo G, Nie Y, Shi Y, Zhou Y, Ren G, Feng B, Liu Z, Pan Y, Li T, Guo X, Wu K, Miranda-Vizuete A, Wang X, Fan D.

Antioxid Redox Signal. 2013 Sep 20;19(9):899-911. doi: 10.1089/ars.2012.4736. Epub 2013 Mar 4.


Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-κB pathway.

Lu Y, Zhao X, Luo G, Shen G, Li K, Ren G, Pan Y, Wang X, Fan D.

Cancer Lett. 2015 Jul 28;363(2):119-26. doi: 10.1016/j.canlet.2014.12.048. Epub 2014 Dec 30.


miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway.

Zhang X, Shi H, Tang H, Fang Z, Wang J, Cui S.

Int J Mol Med. 2015 May;35(5):1301-8. doi: 10.3892/ijmm.2015.2126. Epub 2015 Mar 6.


Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.

Yuen HF, Chan KK, Grills C, Murray JT, Platt-Higgins A, Eldin OS, O'Byrne K, Janne P, Fennell DA, Johnston PG, Rudland PS, El-Tanani M.

Clin Cancer Res. 2012 Jan 15;18(2):380-91. doi: 10.1158/1078-0432.CCR-11-2035. Epub 2011 Nov 16.


C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasion.

He X, Tan X, Wang X, Jin H, Liu L, Ma L, Yu H, Fan Z.

Tumour Biol. 2014 Dec;35(12):12181-8. doi: 10.1007/s13277-014-2526-4. Epub 2014 Sep 4.


Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway.

Li XX, Huang LY, Peng JJ, Liang L, Shi DB, Zheng HT, Cai SJ.

Int J Oncol. 2014 Aug;45(2):611-8. doi: 10.3892/ijo.2014.2430. Epub 2014 May 9.


Identification and distribution of thioredoxin-like 2 as the antigen for the monoclonal antibody MC3 specific to colorectal cancer.

Lu Y, Wang X, Liu Z, Jin B, Chu D, Zhai H, Zhang F, Li K, Ren G, Miranda-Vizuete A, Guo X, Fan D.

Proteomics. 2008 Jun;8(11):2220-9. doi: 10.1002/pmic.200700770.


Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3.

Porquet N, Poirier A, Houle F, Pin AL, Gout S, Tremblay PL, Paquet ER, Klinck R, Auger FA, Huot J.

BMC Cancer. 2011 Jul 1;11:285. doi: 10.1186/1471-2407-11-285.


The critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis.

Li D, Wei P, Peng Z, Huang C, Tang H, Jia Z, Cui J, Le X, Huang S, Xie K.

Clin Cancer Res. 2013 Jan 1;19(1):62-72. doi: 10.1158/1078-0432.CCR-12-1588. Epub 2012 Nov 7.


PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling.

Peng L, Xing X, Li W, Qu L, Meng L, Lian S, Jiang B, Wu J, Shou C.

Mol Cancer. 2009 Nov 24;8:110. doi: 10.1186/1476-4598-8-110.


Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma.

Shen Z, Deng H, Fang Y, Zhu X, Ye GT, Yan L, Liu H, Li G.

Oncotarget. 2015 Aug 21;6(24):20672-84.


Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth.

Ponnurangam S, Standing D, Rangarajan P, Subramaniam D.

Mol Cancer Ther. 2013 May;12(5):598-609. doi: 10.1158/1535-7163.MCT-12-0907. Epub 2013 Feb 20.


Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell.

Jia ZC, Wan YL, Tang JQ, Dai Y, Liu YC, Wang X, Zhu J.

Int J Colorectal Dis. 2012 Apr;27(4):437-45. doi: 10.1007/s00384-011-1351-0. Epub 2011 Nov 12.


Knockdown of lymphoid enhancer factor 1 inhibits colon cancer progression in vitro and in vivo.

Wang WJ, Yao Y, Jiang LL, Hu TH, Ma JQ, Liao ZJ, Yao JT, Li DF, Wang SH, Nan KJ.

PLoS One. 2013 Oct 2;8(10):e76596. doi: 10.1371/journal.pone.0076596. eCollection 2013.


Restoration of transforming growth factor-beta receptor II expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo.

Liu XQ, Rajput A, Geng L, Ongchin M, Chaudhuri A, Wang J.

J Biol Chem. 2011 May 6;286(18):16082-90. doi: 10.1074/jbc.M111.221697. Epub 2011 Mar 17.


KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis.

Li D, Peng Z, Tang H, Wei P, Kong X, Yan D, Huang F, Li Q, Le X, Li Q, Xie K.

Clin Cancer Res. 2011 Jun 1;17(11):3558-68. doi: 10.1158/1078-0432.CCR-10-2729. Epub 2011 Apr 29.


TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer.

Wei P, Zhang N, Xu Y, Li X, Shi D, Wang Y, Li D, Cai S.

J Transl Med. 2013 Dec 17;11:313. doi: 10.1186/1479-5876-11-313.


ACK1 promotes gastric cancer epithelial-mesenchymal transition and metastasis through AKT-POU2F1-ECD signalling.

Xu SH, Huang JZ, Xu ML, Yu G, Yin XF, Chen D, Yan GR.

J Pathol. 2015 Jun;236(2):175-85. doi: 10.1002/path.4515. Epub 2015 Mar 9.

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