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Results: 1 to 20 of 122

1.

Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model.

Benezra M, Hambardzumyan D, Penate-Medina O, Veach DR, Pillarsetty N, Smith-Jones P, Phillips E, Ozawa T, Zanzonico PB, Longo V, Holland EC, Larson SM, Bradbury MS.

Neoplasia. 2012 Dec;14(12):1132-43.

PMID:
23308046
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib.

Dumont RA, Hildebrandt I, Su H, Haubner R, Reischl G, Czernin JG, Mischel PS, Weber WA.

Cancer Res. 2009 Apr 1;69(7):3173-9. doi: 10.1158/0008-5472.CAN-08-3390. Epub 2009 Mar 24.

PMID:
19318569
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.

Agarwal S, Mittapalli RK, Zellmer DM, Gallardo JL, Donelson R, Seiler C, Decker SA, Santacruz KS, Pokorny JL, Sarkaria JN, Elmquist WF, Ohlfest JR.

Mol Cancer Ther. 2012 Oct;11(10):2183-92. doi: 10.1158/1535-7163.MCT-12-0552. Epub 2012 Aug 13.

PMID:
22891038
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Co-administration of NVP-AEW541 and dasatinib induces mitochondrial-mediated apoptosis through Bax activation in malignant human glioma cell lines.

Premkumar DR, Jane EP, Pollack IF.

Int J Oncol. 2010 Sep;37(3):633-43.

PMID:
20664932
[PubMed - indexed for MEDLINE]
5.

Dynamic small-animal PET imaging of tumor proliferation with 3'-deoxy-3'-18F-fluorothymidine in a genetically engineered mouse model of high-grade gliomas.

Bradbury MS, Hambardzumyan D, Zanzonico PB, Schwartz J, Cai S, Burnazi EM, Longo V, Larson SM, Holland EC.

J Nucl Med. 2008 Mar;49(3):422-9. doi: 10.2967/jnumed.107.047092. Epub 2008 Feb 20.

PMID:
18287265
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.

Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, Bading JR, Laug WE, Conti PS.

J Nucl Med. 2004 Oct;45(10):1776-83.

PMID:
15471848
[PubMed - indexed for MEDLINE]
Free Article
8.

Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL), a multi-targeted kinase inhibitor.

Luo FR, Barrett YC, Yang Z, Camuso A, McGlinchey K, Wen ML, Smykla R, Fager K, Wild R, Palme H, Galbraith S, Blackwood-Chirchir A, Lee FY.

Cancer Chemother Pharmacol. 2008 Nov;62(6):1065-74. doi: 10.1007/s00280-008-0699-5. Epub 2008 Feb 27.

PMID:
18301894
[PubMed - indexed for MEDLINE]
9.

Dasatinib, a small molecule inhibitor of the Src kinase, reduces the growth and activates apoptosis in pre-neoplastic Barrett's esophagus cell lines: evidence for a noninvasive treatment of high-grade dysplasia.

Inge LJ, Fowler AJ, Paquette KM, Richer AL, Tran N, Bremner RM.

J Thorac Cardiovasc Surg. 2013 Feb;145(2):531-8. doi: 10.1016/j.jtcvs.2012.10.041. Epub 2012 Nov 9.

PMID:
23142123
[PubMed - indexed for MEDLINE]
10.

Imaging of human epidermal growth factor receptor type 2 expression with 18F-labeled affibody molecule ZHER2:2395 in a mouse model for ovarian cancer.

Heskamp S, Laverman P, Rosik D, Boschetti F, van der Graaf WT, Oyen WJ, van Laarhoven HW, Tolmachev V, Boerman OC.

J Nucl Med. 2012 Jan;53(1):146-53. doi: 10.2967/jnumed.111.093047. Epub 2011 Dec 15.

PMID:
22173842
[PubMed - indexed for MEDLINE]
Free Article
11.

In vivo PET/CT in a human glioblastoma chicken chorioallantoic membrane model: a new tool for oncology and radiotracer development.

Warnock G, Turtoi A, Blomme A, Bretin F, Bahri MA, Lemaire C, Libert LC, Seret AE, Luxen A, Castronovo V, Plenevaux AR.

J Nucl Med. 2013 Oct;54(10):1782-8. doi: 10.2967/jnumed.112.117150. Epub 2013 Aug 22.

PMID:
23970367
[PubMed - indexed for MEDLINE]
12.

The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.

Awde AR, Boisgard R, Thézé B, Dubois A, Zheng J, Dollé F, Jacobs AH, Tavitian B, Winkeler A.

J Nucl Med. 2013 Dec;54(12):2125-31. doi: 10.2967/jnumed.112.118794. Epub 2013 Nov 8.

PMID:
24212976
[PubMed - indexed for MEDLINE]
13.

Role of Src tyrosine kinases in experimental pulmonary hypertension.

Pullamsetti SS, Berghausen EM, Dabral S, Tretyn A, Butrous E, Savai R, Butrous G, Dahal BK, Brandes RP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Rosenkranz S, Schermuly RT.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1354-65. doi: 10.1161/ATVBAHA.112.248500. Epub 2012 Apr 19.

PMID:
22516066
[PubMed - indexed for MEDLINE]
Free Article
14.

A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging.

Jiang H, Moore SJ, Liu S, Liu H, Miao Z, Cochran FV, Liu Y, Tian M, Cochran JR, Zhang H, Cheng Z.

Amino Acids. 2013 Feb;44(2):673-81. doi: 10.1007/s00726-012-1391-y. Epub 2012 Sep 4.

PMID:
22945905
[PubMed - indexed for MEDLINE]
15.

Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.

Roberts WG, Whalen PM, Soderstrom E, Moraski G, Lyssikatos JP, Wang HF, Cooper B, Baker DA, Savage D, Dalvie D, Atherton JA, Ralston S, Szewc R, Kath JC, Lin J, Soderstrom C, Tkalcevic G, Cohen BD, Pollack V, Barth W, Hungerford W, Ung E.

Cancer Res. 2005 Feb 1;65(3):957-66.

PMID:
15705896
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

Dewaele B, Wasag B, Cools J, Sciot R, Prenen H, Vandenberghe P, Wozniak A, Schöffski P, Marynen P, Debiec-Rychter M.

Clin Cancer Res. 2008 Sep 15;14(18):5749-58. doi: 10.1158/1078-0432.CCR-08-0533.

PMID:
18794084
[PubMed - indexed for MEDLINE]
Free Article
18.

Comparison of (18)F-labeled CXCR4 antagonist peptides for PET imaging of CXCR4 expression.

Zhang XX, Sun Z, Guo J, Wang Z, Wu C, Niu G, Ma Y, Kiesewetter DO, Chen X.

Mol Imaging Biol. 2013 Dec;15(6):758-67. doi: 10.1007/s11307-013-0640-0. Erratum in: Mol Imaging Biol. 2013 Dec;15(6):788.

PMID:
23636490
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect.

Zhan C, Gu B, Xie C, Li J, Liu Y, Lu W.

J Control Release. 2010 Apr 2;143(1):136-42. doi: 10.1016/j.jconrel.2009.12.020. Epub 2010 Jan 7.

PMID:
20056123
[PubMed - indexed for MEDLINE]
20.

Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake.

Monazzam A, Razifar P, Ide S, Rugaard Jensen M, Josephsson R, Blomqvist C, Langström B, Bergström M.

Nucl Med Biol. 2009 Apr;36(3):335-42. doi: 10.1016/j.nucmedbio.2008.12.009.

PMID:
19324279
[PubMed - indexed for MEDLINE]

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