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Results: 1 to 20 of 144

1.

Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila.

Song S, Jang S, Park J, Bang S, Choi S, Kwon KY, Zhuang X, Kim E, Chung J.

J Biol Chem. 2013 Feb 22;288(8):5660-72. doi: 10.1074/jbc.M112.430801. Epub 2013 Jan 9.

PMID:
23303188
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.

Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.

J Cell Biol. 2010 Apr 19;189(2):211-21. doi: 10.1083/jcb.200910140.

PMID:
20404107
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.

PLoS Genet. 2012;8(3):e1002537. doi: 10.1371/journal.pgen.1002537. Epub 2012 Mar 1.

PMID:
22396657
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
[PubMed - indexed for MEDLINE]
5.

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

Rakovic A, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C.

J Biol Chem. 2013 Jan 25;288(4):2223-37. doi: 10.1074/jbc.M112.391680. Epub 2012 Dec 4.

PMID:
23212910
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM.

Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080.

PMID:
22724072
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):378-83. doi: 10.1073/pnas.0911187107. Epub 2009 Dec 4.

PMID:
19966284
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.

Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R.

Hum Mol Genet. 2013 Jun 15;22(12):2423-34. doi: 10.1093/hmg/ddt095. Epub 2013 Feb 27.

PMID:
23449626
[PubMed - indexed for MEDLINE]
Free Article
9.

Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.

Iguchi M, Kujuro Y, Okatsu K, Koyano F, Kosako H, Kimura M, Suzuki N, Uchiyama S, Tanaka K, Matsuda N.

J Biol Chem. 2013 Jul 26;288(30):22019-32. doi: 10.1074/jbc.M113.467530. Epub 2013 Jun 10.

PMID:
23754282
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

Costa AC, Loh SH, Martins LM.

Cell Death Dis. 2013 Jan 17;4:e467. doi: 10.1038/cddis.2012.205.

PMID:
23328674
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients.

Rakovic A, Grünewald A, Seibler P, Ramirez A, Kock N, Orolicki S, Lohmann K, Klein C.

Hum Mol Genet. 2010 Aug 15;19(16):3124-37. doi: 10.1093/hmg/ddq215. Epub 2010 May 27.

PMID:
20508036
[PubMed - indexed for MEDLINE]
Free Article
12.

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.

Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.

FEBS Lett. 2010 Mar 19;584(6):1073-9. doi: 10.1016/j.febslet.2010.02.016. Epub 2010 Feb 12.

PMID:
20153330
[PubMed - indexed for MEDLINE]
Free Article
13.

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila.

Deng H, Dodson MW, Huang H, Guo M.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14503-8. doi: 10.1073/pnas.0803998105. Epub 2008 Sep 17.

PMID:
18799731
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Imai Y, Kanao T, Sawada T, Kobayashi Y, Moriwaki Y, Ishida Y, Takeda K, Ichijo H, Lu B, Takahashi R.

PLoS Genet. 2010 Dec 2;6(12):e1001229. doi: 10.1371/journal.pgen.1001229.

PMID:
21151955
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations.

Geisler S, Holmström KM, Treis A, Skujat D, Weber SS, Fiesel FC, Kahle PJ, Springer W.

Autophagy. 2010 Oct;6(7):871-8. Epub 2010 Oct 3.

PMID:
20798600
[PubMed - indexed for MEDLINE]
Free Article
16.

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation.

Kim Y, Park J, Kim S, Song S, Kwon SK, Lee SH, Kitada T, Kim JM, Chung J.

Biochem Biophys Res Commun. 2008 Dec 19;377(3):975-80. doi: 10.1016/j.bbrc.2008.10.104. Epub 2008 Oct 26.

PMID:
18957282
[PubMed - indexed for MEDLINE]
17.

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy.

Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW.

Hum Mol Genet. 2010 Dec 15;19(24):4861-70. doi: 10.1093/hmg/ddq419. Epub 2010 Sep 24. Erratum in: Hum Mol Genet. 2013 Apr 15;22(8):1697.

PMID:
20871098
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

[Molecular genetics of PINK1].

Funayama M, Hattori N.

Brain Nerve. 2007 Aug;59(8):831-8. Review. Japanese.

PMID:
17713119
[PubMed - indexed for MEDLINE]
19.

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling.

Sha D, Chin LS, Li L.

Hum Mol Genet. 2010 Jan 15;19(2):352-63. doi: 10.1093/hmg/ddp501. Epub 2009 Oct 30.

PMID:
19880420
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Molecular interaction between parkin and PINK1 in mammalian neuronal cells.

Um JW, Stichel-Gunkel C, Lübbert H, Lee G, Chung KC.

Mol Cell Neurosci. 2009 Apr;40(4):421-32. doi: 10.1016/j.mcn.2008.12.010. Epub 2009 Jan 8.

PMID:
19167501
[PubMed - indexed for MEDLINE]

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