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Results: 1 to 20 of 110

1.

Regulator of G-protein signaling 5 controls blood pressure homeostasis and vessel wall remodeling.

Holobotovskyy V, Manzur M, Tare M, Burchell J, Bolitho E, Viola H, Hool LC, Arnolda LF, McKitrick DJ, Ganss R.

Circ Res. 2013 Mar 1;112(5):781-91. doi: 10.1161/CIRCRESAHA.111.300142. Epub 2013 Jan 9.

PMID:
23303165
[PubMed - indexed for MEDLINE]
Free Article
2.

PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.

Gunaje JJ, Bahrami AJ, Schwartz SM, Daum G, Mahoney WM Jr.

Am J Physiol Cell Physiol. 2011 Aug;301(2):C478-89. doi: 10.1152/ajpcell.00348.2010. Epub 2011 May 18.

PMID:
21593453
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy.

Wang X, Adams LD, Pabón LM, Mahoney WM Jr, Beaudry D, Gunaje J, Geary RL, Deblois D, Schwartz SM.

J Mol Cell Cardiol. 2008 Mar;44(3):539-50. doi: 10.1016/j.yjmcc.2007.11.019. Epub 2007 Dec 8.

PMID:
18207159
[PubMed - indexed for MEDLINE]
4.

PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity.

Ketsawatsomkron P, Lorca RA, Keen HL, Weatherford ET, Liu X, Pelham CJ, Grobe JL, Faraci FM, England SK, Sigmund CD.

Circ Res. 2012 Nov 9;111(11):1446-58. doi: 10.1161/CIRCRESAHA.112.271577. Epub 2012 Sep 7.

PMID:
22962432
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Rgs5 targeting leads to chronic low blood pressure and a lean body habitus.

Cho H, Park C, Hwang IY, Han SB, Schimel D, Despres D, Kehrl JH.

Mol Cell Biol. 2008 Apr;28(8):2590-7. doi: 10.1128/MCB.01889-07. Epub 2008 Feb 11.

PMID:
18268011
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload.

Li H, He C, Feng J, Zhang Y, Tang Q, Bian Z, Bai X, Zhou H, Jiang H, Heximer SP, Qin M, Huang H, Liu PP, Huang C.

Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13818-23. doi: 10.1073/pnas.1008397107. Epub 2010 Jul 19.

PMID:
20643937
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Regulator of G protein signaling 5 marks peripheral arterial smooth muscle cells and is downregulated in atherosclerotic plaque.

Li J, Adams LD, Wang X, Pabon L, Schwartz SM, Sane DC, Geary RL.

J Vasc Surg. 2004 Sep;40(3):519-28.

PMID:
15337883
[PubMed - indexed for MEDLINE]
8.

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure.

Tang KM, Wang GR, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME.

Nat Med. 2003 Dec;9(12):1506-12. Epub 2003 Nov 9. Erratum in: Nat Med. 2004 Jan;10(1):105. Tang, Mary [corrected to Tang, K Mary]; Wang, Guang [corrected to Wang, Guang-rong].

PMID:
14608379
[PubMed - indexed for MEDLINE]
9.

Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells.

Wang Q, Liu M, Mullah B, Siderovski DP, Neubig RR.

J Biol Chem. 2002 Jul 12;277(28):24949-58. Epub 2002 May 2.

PMID:
12006602
[PubMed - indexed for MEDLINE]
Free Article
10.

Vascular hypertrophy-associated hypertension of profilin1 transgenic mouse model leads to functional remodeling of peripheral arteries.

Hassona MD, Abouelnaga ZA, Elnakish MT, Awad MM, Alhaj M, Goldschmidt-Clermont PJ, Hassanain H.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2112-20. doi: 10.1152/ajpheart.00016.2010. Epub 2010 Apr 16.

PMID:
20400688
[PubMed - indexed for MEDLINE]
Free Article
11.

Activation of cold-sensing transient receptor potential melastatin subtype 8 antagonizes vasoconstriction and hypertension through attenuating RhoA/Rho kinase pathway.

Sun J, Yang T, Wang P, Ma S, Zhu Z, Pu Y, Li L, Zhao Y, Xiong S, Liu D, Zhu Z.

Hypertension. 2014 Jun;63(6):1354-63. doi: 10.1161/HYPERTENSIONAHA.113.02573. Epub 2014 Mar 17.

PMID:
24637663
[PubMed - indexed for MEDLINE]
12.

Regulator of G protein signaling 5: a new player in vascular remodeling.

Manzur M, Ganss R.

Trends Cardiovasc Med. 2009 Jan;19(1):26-30. doi: 10.1016/j.tcm.2009.04.002. Review.

PMID:
19467451
[PubMed - indexed for MEDLINE]
13.

Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance.

Deng W, Wang X, Xiao J, Chen K, Zhou H, Shen D, Li H, Tang Q.

PLoS One. 2012;7(1):e30256. doi: 10.1371/journal.pone.0030256. Epub 2012 Jan 17.

PMID:
22272317
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling.

Keys JR, Zhou RH, Harris DM, Druckman CA, Eckhart AD.

Circulation. 2005 Aug 23;112(8):1145-53. Epub 2005 Aug 15.

PMID:
16103237
[PubMed - indexed for MEDLINE]
Free Article
15.

Rho kinase-mediated vasoconstriction in pulmonary hypertension.

McMurtry IF, Abe K, Ota H, Fagan KA, Oka M.

Adv Exp Med Biol. 2010;661:299-308. doi: 10.1007/978-1-60761-500-2_19. Review.

PMID:
20204738
[PubMed - indexed for MEDLINE]
16.

Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation.

Zhao YD, Cai L, Mirza MK, Huang X, Geenen DL, Hofmann F, Yuan JX, Zhao YY.

Am J Pathol. 2012 Jun;180(6):2268-75. doi: 10.1016/j.ajpath.2012.02.016.

PMID:
22632818
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling.

Sun X, Kaltenbronn KM, Steinberg TH, Blumer KJ.

Mol Pharmacol. 2005 Mar;67(3):631-9. Epub 2004 Nov 24.

PMID:
15563583
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulator of G protein signalling 2 ameliorates angiotensin II-induced hypertension in mice.

Hercule HC, Tank J, Plehm R, Wellner M, da Costa Goncalves AC, Gollasch M, Diedrich A, Jordan J, Luft FC, Gross V.

Exp Physiol. 2007 Nov;92(6):1014-22. Epub 2007 Jul 20.

PMID:
17644703
[PubMed - indexed for MEDLINE]
Free Article
19.

Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation.

Cho H, Kozasa T, Bondjers C, Betsholtz C, Kehrl JH.

FASEB J. 2003 Mar;17(3):440-2. Epub 2003 Jan 2.

PMID:
12514120
[PubMed - indexed for MEDLINE]
Free Article
20.

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.

Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ.

J Clin Invest. 2003 Feb;111(4):445-52.

PMID:
12588882
[PubMed - indexed for MEDLINE]
Free PMC Article
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