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A virally encoded small peptide regulates RTA stability and facilitates Kaposi's sarcoma-associated herpesvirus lytic replication.

Jaber T, Yuan Y.

J Virol. 2013 Mar;87(6):3461-70. doi: 10.1128/JVI.02746-12. Epub 2013 Jan 9.


Overexpression of the kaposi's sarcoma-associated herpesvirus transactivator K-Rta can complement a K-bZIP deletion BACmid and yields an enhanced growth phenotype.

Kato-Noah T, Xu Y, Rossetto CC, Colletti K, Papouskov√° I, Pari GS.

J Virol. 2007 Dec;81(24):13519-32. Epub 2007 Oct 3.


X box binding protein XBP-1s transactivates the Kaposi's sarcoma-associated herpesvirus (KSHV) ORF50 promoter, linking plasma cell differentiation to KSHV reactivation from latency.

Wilson SJ, Tsao EH, Webb BL, Ye H, Dalton-Griffin L, Tsantoulas C, Gale CV, Du MQ, Whitehouse A, Kellam P.

J Virol. 2007 Dec;81(24):13578-86. Epub 2007 Oct 10.


Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway.

Gould F, Harrison SM, Hewitt EW, Whitehouse A.

J Virol. 2009 Jul;83(13):6727-38. doi: 10.1128/JVI.00351-09. Epub 2009 Apr 15.


Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus.

He Z, Liu Y, Liang D, Wang Z, Robertson ES, Lan K.

J Virol. 2010 Feb;84(4):2047-62. doi: 10.1128/JVI.01984-09. Epub 2009 Nov 25.


KSHV PAN RNA associates with demethylases UTX and JMJD3 to activate lytic replication through a physical interaction with the virus genome.

Rossetto CC, Pari G.

PLoS Pathog. 2012;8(5):e1002680. doi: 10.1371/journal.ppat.1002680. Epub 2012 May 10.


Kaposi's sarcoma-associated herpesvirus transactivator RTA promotes degradation of the repressors to regulate viral lytic replication.

Yang Z, Yan Z, Wood C.

J Virol. 2008 Apr;82(7):3590-603. doi: 10.1128/JVI.02229-07. Epub 2008 Jan 23.


An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis.

Prasad A, Lu M, Lukac DM, Zeichner SL.

J Virol. 2012 Apr;86(8):4404-19. doi: 10.1128/JVI.06617-11. Epub 2012 Feb 15.


Enhancement of autophagy during lytic replication by the Kaposi's sarcoma-associated herpesvirus replication and transcription activator.

Wen HJ, Yang Z, Zhou Y, Wood C.

J Virol. 2010 Aug;84(15):7448-58. doi: 10.1128/JVI.00024-10. Epub 2010 May 19.


Activation of the Kaposi's sarcoma-associated herpesvirus major latency locus by the lytic switch protein RTA (ORF50).

Matsumura S, Fujita Y, Gomez E, Tanese N, Wilson AC.

J Virol. 2005 Jul;79(13):8493-505.

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