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Results: 1 to 20 of 311

1.

Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.

Kumar M, Roe K, Orillo B, Muruve DA, Nerurkar VR, Gale M Jr, Verma S.

J Virol. 2013 Apr;87(7):3655-67. doi: 10.1128/JVI.02667-12. Epub 2013 Jan 9.

PMID:
23302887
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection.

Ramos HJ, Lanteri MC, Blahnik G, Negash A, Suthar MS, Brassil MM, Sodhi K, Treuting PM, Busch MP, Norris PJ, Gale M Jr.

PLoS Pathog. 2012;8(11):e1003039. doi: 10.1371/journal.ppat.1003039. Epub 2012 Nov 29.

PMID:
23209411
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IPS-1 is essential for the control of West Nile virus infection and immunity.

Suthar MS, Ma DY, Thomas S, Lund JM, Zhang N, Daffis S, Rudensky AY, Bevan MJ, Clark EA, Kaja MK, Diamond MS, Gale M Jr.

PLoS Pathog. 2010 Feb 5;6(2):e1000757. doi: 10.1371/journal.ppat.1000757.

PMID:
20140199
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.

van de Veerdonk FL, Joosten LA, Shaw PJ, Smeekens SP, Malireddi RK, van der Meer JW, Kullberg BJ, Netea MG, Kanneganti TD.

Eur J Immunol. 2011 Aug;41(8):2260-8. doi: 10.1002/eji.201041226. Epub 2011 Jul 4.

PMID:
21681738
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

PMID:
23625200
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes.

Suthar MS, Brassil MM, Blahnik G, McMillan A, Ramos HJ, Proll SC, Belisle SE, Katze MG, Gale M Jr.

PLoS Pathog. 2013 Feb;9(2):e1003168. doi: 10.1371/journal.ppat.1003168. Epub 2013 Feb 7.

PMID:
23544010
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system.

Szretter KJ, Daffis S, Patel J, Suthar MS, Klein RS, Gale M Jr, Diamond MS.

J Virol. 2010 Dec;84(23):12125-38. doi: 10.1128/JVI.01026-10. Epub 2010 Sep 29.

PMID:
20881045
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293. Epub 2013 Aug 21.

PMID:
23966627
[PubMed - indexed for MEDLINE]
Free Article
9.

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus.

Kumar M, Roe K, Nerurkar PV, Orillo B, Thompson KS, Verma S, Nerurkar VR.

J Neuroinflammation. 2014 Apr 21;11:80. doi: 10.1186/1742-2094-11-80.

PMID:
24750819
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Critical role for the AIM2 inflammasome during acute CNS bacterial infection.

Hanamsagar R, Aldrich A, Kielian T.

J Neurochem. 2014 May;129(4):704-11. doi: 10.1111/jnc.12669. Epub 2014 Feb 19.

PMID:
24484406
[PubMed - indexed for MEDLINE]
11.

Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system.

Shrestha B, Zhang B, Purtha WE, Klein RS, Diamond MS.

J Virol. 2008 Sep;82(18):8956-64. doi: 10.1128/JVI.01118-08. Epub 2008 Jul 16.

PMID:
18632856
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.

Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M Jr, Diamond MS.

J Virol. 2008 Sep;82(17):8465-75. doi: 10.1128/JVI.00918-08. Epub 2008 Jun 18.

PMID:
18562536
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.

PMID:
23110696
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.

Thackray LB, Shrestha B, Richner JM, Miner JJ, Pinto AK, Lazear HM, Gale M Jr, Diamond MS.

J Virol. 2014 Oct;88(19):11007-21. doi: 10.1128/JVI.01545-14. Epub 2014 Jul 16.

PMID:
25031348
[PubMed - indexed for MEDLINE]
16.

Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus.

Kumar M, Roe K, Nerurkar PV, Namekar M, Orillo B, Verma S, Nerurkar VR.

PLoS One. 2012;7(8):e44682. doi: 10.1371/journal.pone.0044682. Epub 2012 Aug 31.

PMID:
22953001
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921. Epub 2012 Jan 19.

PMID:
22213227
[PubMed - indexed for MEDLINE]
18.

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis.

Mariathasan S, Weiss DS, Dixit VM, Monack DM.

J Exp Med. 2005 Oct 17;202(8):1043-9.

PMID:
16230474
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection.

Glass WG, Lim JK, Cholera R, Pletnev AG, Gao JL, Murphy PM.

J Exp Med. 2005 Oct 17;202(8):1087-98.

PMID:
16230476
[PubMed - indexed for MEDLINE]
Free PMC Article
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