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Results: 1 to 20 of 140

1.

PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.

Glas J, Seiderer J, Czamara D, Pasciuto G, Diegelmann J, Wetzke M, Olszak T, Wolf C, Müller-Myhsok B, Balschun T, Achkar JP, Kamboh MI, Franke A, Duerr RH, Brand S.

PLoS One. 2012;7(12):e52873. doi: 10.1371/journal.pone.0052873. Epub 2012 Dec 27.

PMID:
23300802
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.

Glas J, Wagner J, Seiderer J, Olszak T, Wetzke M, Beigel F, Tillack C, Stallhofer J, Friedrich M, Steib C, Göke B, Ochsenkühn T, Karbalai N, Diegelmann J, Czamara D, Brand S.

PLoS One. 2012;7(3):e33682. doi: 10.1371/journal.pone.0033682. Epub 2012 Mar 21.

PMID:
22457781
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.

Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M.

PLoS Genet. 2007 Apr 20;3(4):e58. Epub 2007 Mar 5.

PMID:
17447842
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.

Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Mar;104(3):665-72. doi: 10.1038/ajg.2008.65. Epub 2009 Feb 3.

PMID:
19262523
[PubMed - indexed for MEDLINE]
5.

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2008 Mar;103(3):682-91. Epub 2007 Dec 20.

PMID:
18162085
[PubMed - indexed for MEDLINE]
6.

IRGM variants and susceptibility to inflammatory bowel disease in the German population.

Glas J, Seiderer J, Bues S, Stallhofer J, Fries C, Olszak T, Tsekeri E, Wetzke M, Beigel F, Steib C, Friedrich M, Göke B, Diegelmann J, Czamara D, Brand S.

PLoS One. 2013;8(1):e54338. doi: 10.1371/journal.pone.0054338. Epub 2013 Jan 24.

PMID:
23365659
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Study of chromosomal region 5p13.1 in Crohn's disease, ulcerative colitis, and rheumatoid arthritis.

Perdigones N, Martín E, Robledo G, Lamas JR, Taxonera C, Díaz-Rubio M, de la Concha EG, López-Nevot MA, García A, Gómez-García M, Fernández-Gutiérrez B, Martín J, Urcelay E.

Hum Immunol. 2010 Aug;71(8):826-8. doi: 10.1016/j.humimm.2010.05.010. Epub 2010 May 16.

PMID:
20561984
[PubMed - indexed for MEDLINE]
8.

The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.

Glas J, Seiderer J, Bayrle C, Wetzke M, Fries C, Tillack C, Olszak T, Beigel F, Steib C, Friedrich M, Diegelmann J, Czamara D, Brand S.

PLoS One. 2011;6(12):e29309. doi: 10.1371/journal.pone.0029309. Epub 2011 Dec 29.

PMID:
22242114
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie CM, Soars D, Bagnall R, Mirza MM, Sanderson J, Forbes A, Mansfield JC, Lewis CM, Schreiber S, Mathew CG.

Gastroenterology. 2007 May;132(5):1665-71. Epub 2007 Mar 24.

PMID:
17484864
[PubMed - indexed for MEDLINE]
10.

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

Glas J, Seiderer J, Wetzke M, Konrad A, Török HP, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Maier K, Griga T, Klein W, Epplen JT, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Brand S.

PLoS One. 2007 Sep 5;2(9):e819.

PMID:
17786191
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.

Török HP, Glas J, Endres I, Tonenchi L, Teshome MY, Wetzke M, Klein W, Lohse P, Ochsenkühn T, Folwaczny M, Göke B, Folwaczny C, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1723-33. doi: 10.1038/ajg.2009.184. Epub 2009 May 19.

PMID:
19455129
[PubMed - indexed for MEDLINE]
12.

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.

Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, Schreiber S, Dijkstra G, Franke A, Nolte IM, Rutgeerts P, Wijmenga C, Vermeire S.

Am J Gastroenterol. 2009 Mar;104(3):630-8. doi: 10.1038/ajg.2008.112. Epub 2009 Jan 27.

PMID:
19174780
[PubMed - indexed for MEDLINE]
13.

Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.

Diegelmann J, Czamara D, Le Bras E, Zimmermann E, Olszak T, Bedynek A, Göke B, Franke A, Glas J, Brand S.

PLoS One. 2013 Nov 5;8(11):e77773. doi: 10.1371/journal.pone.0077773. eCollection 2013.

PMID:
24223725
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Investigation of multiple susceptibility loci for inflammatory bowel disease in an Italian cohort of patients.

Latiano A, Palmieri O, Latiano T, Corritore G, Bossa F, Martino G, Biscaglia G, Scimeca D, Valvano MR, Pastore M, Marseglia A, D'Incà R, Andriulli A, Annese V.

PLoS One. 2011;6(7):e22688. doi: 10.1371/journal.pone.0022688. Epub 2011 Jul 27.

PMID:
21818367
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.

Glas J, Seiderer J, Fischer D, Tengler B, Pfennig S, Wetzke M, Beigel F, Olszak T, Weidinger M, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Diegelmann J, Czamara D, Brand S.

Inflamm Bowel Dis. 2011 Sep;17(9):1917-24. doi: 10.1002/ibd.21562. Epub 2010 Dec 3.

PMID:
21830270
[PubMed - indexed for MEDLINE]
16.

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

Weersma RK, Zhou L, Nolte IM, van der Steege G, van Dullemen HM, Oosterom E, Bok L, Peppelenbosch MP, Faber KN, Kleibeuker JH, Dijkstra G.

Inflamm Bowel Dis. 2008 Dec;14(12):1615-22. doi: 10.1002/ibd.20610.

PMID:
18668679
[PubMed - indexed for MEDLINE]
17.

PTGER4 modulating variants in Crohn's disease.

Prager M, Büttner J, Büning C.

Int J Colorectal Dis. 2014 Aug;29(8):909-15. doi: 10.1007/s00384-014-1881-3. Epub 2014 May 3.

PMID:
24793213
[PubMed - in process]
18.

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.

Seiderer J, Elben I, Diegelmann J, Glas J, Stallhofer J, Tillack C, Pfennig S, Jürgens M, Schmechel S, Konrad A, Göke B, Ochsenkühn T, Müller-Myhsok B, Lohse P, Brand S.

Inflamm Bowel Dis. 2008 Apr;14(4):437-45.

PMID:
18088064
[PubMed - indexed for MEDLINE]
19.

Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease.

Latiano A, Palmieri O, Corritore G, Valvano MR, Bossa F, Cucchiara S, Castro M, Riegler G, De Venuto D, D'Incà R, Andriulli A, Annese V.

Inflamm Bowel Dis. 2010 Jul;16(7):1108-17. doi: 10.1002/ibd.21176.

PMID:
20024904
[PubMed - indexed for MEDLINE]
20.

Analysis of IL12B gene variants in inflammatory bowel disease.

Glas J, Seiderer J, Wagner J, Olszak T, Fries C, Tillack C, Friedrich M, Beigel F, Stallhofer J, Steib C, Wetzke M, Göke B, Ochsenkühn T, Diegelmann J, Czamara D, Brand S.

PLoS One. 2012;7(3):e34349. doi: 10.1371/journal.pone.0034349. Epub 2012 Mar 30.

PMID:
22479607
[PubMed - indexed for MEDLINE]
Free PMC Article

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