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Results: 1 to 20 of 124

1.

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET.

Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D.

Development. 2013 Feb 1;140(3):519-29. doi: 10.1242/dev.087585.

PMID:
23293284
[PubMed - indexed for MEDLINE]
Free Article
2.

KAP1 controls endogenous retroviruses in embryonic stem cells.

Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D.

Nature. 2010 Jan 14;463(7278):237-40. doi: 10.1038/nature08674.

PMID:
20075919
[PubMed - indexed for MEDLINE]
3.

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

Matsui T, Leung D, Miyashita H, Maksakova IA, Miyachi H, Kimura H, Tachibana M, Lorincz MC, Shinkai Y.

Nature. 2010 Apr 8;464(7290):927-31. doi: 10.1038/nature08858. Epub 2010 Feb 17. Erratum in: Nature. 2014 Sep 4;513(7516):128.

PMID:
20164836
[PubMed - indexed for MEDLINE]
4.

The KRAB-ZFP/KAP1 system contributes to the early embryonic establishment of site-specific DNA methylation patterns maintained during development.

Quenneville S, Turelli P, Bojkowska K, Raclot C, Offner S, Kapopoulou A, Trono D.

Cell Rep. 2012 Oct 25;2(4):766-73. doi: 10.1016/j.celrep.2012.08.043. Epub 2012 Oct 4.

PMID:
23041315
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing.

Leung DC, Dong KB, Maksakova IA, Goyal P, Appanah R, Lee S, Tachibana M, Shinkai Y, Lehnertz B, Mager DL, Rossi F, Lorincz MC.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5718-23. doi: 10.1073/pnas.1014660108. Epub 2011 Mar 22.

PMID:
21427230
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells.

Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J, Pfaff SL, Trono D.

Genome Res. 2013 Mar;23(3):452-61. doi: 10.1101/gr.147678.112. Epub 2012 Dec 10.

PMID:
23233547
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading.

Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D.

PLoS Genet. 2010 Mar 5;6(3):e1000869. doi: 10.1371/journal.pgen.1000869.

PMID:
20221260
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

Silencing of endogenous retroviruses: when and why do histone marks predominate?

Leung DC, Lorincz MC.

Trends Biochem Sci. 2012 Apr;37(4):127-33. doi: 10.1016/j.tibs.2011.11.006. Epub 2011 Dec 15.

PMID:
22178137
[PubMed - indexed for MEDLINE]
10.

Histone H3-K9 methyltransferase ESET is essential for early development.

Dodge JE, Kang YK, Beppu H, Lei H, Li E.

Mol Cell Biol. 2004 Mar;24(6):2478-86.

PMID:
14993285
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Zfp819, a novel KRAB-zinc finger protein, interacts with KAP1 and functions in genomic integrity maintenance of mouse embryonic stem cells.

Tan X, Xu X, Elkenani M, Smorag L, Zechner U, Nolte J, Engel W, Pantakani DV.

Stem Cell Res. 2013 Nov;11(3):1045-59. doi: 10.1016/j.scr.2013.07.006. Epub 2013 Jul 30.

PMID:
23954693
[PubMed - indexed for MEDLINE]
12.

Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells.

Liu S, Brind'Amour J, Karimi MM, Shirane K, Bogutz A, Lefebvre L, Sasaki H, Shinkai Y, Lorincz MC.

Genes Dev. 2014 Sep 15;28(18):2041-55. doi: 10.1101/gad.244848.114.

PMID:
25228647
[PubMed - indexed for MEDLINE]
13.

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.

Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ 3rd.

Genes Dev. 2002 Apr 15;16(8):919-32.

PMID:
11959841
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies.

Briers S, Crawford C, Bickmore WA, Sutherland HG.

J Cell Sci. 2009 Apr 1;122(Pt 7):937-46. doi: 10.1242/jcs.034793. Epub 2009 Mar 3.

PMID:
19258395
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis.

Wiznerowicz M, Jakobsson J, Szulc J, Liao S, Quazzola A, Beermann F, Aebischer P, Trono D.

J Biol Chem. 2007 Nov 23;282(47):34535-41. Epub 2007 Sep 24.

PMID:
17893143
[PubMed - indexed for MEDLINE]
Free Article
16.

In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions.

Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D.

Mol Cell. 2011 Nov 4;44(3):361-72. doi: 10.1016/j.molcel.2011.08.032.

PMID:
22055183
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications.

Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D.

J Virol. 2009 Jun;83(11):5574-80. doi: 10.1128/JVI.00001-09. Epub 2009 Mar 11.

PMID:
19279087
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Evolutionally dynamic L1 regulation in embryonic stem cells.

Castro-Diaz N, Ecco G, Coluccio A, Kapopoulou A, Yazdanpanah B, Friedli M, Duc J, Jang SM, Turelli P, Trono D.

Genes Dev. 2014 Jul 1;28(13):1397-409. doi: 10.1101/gad.241661.114. Epub 2014 Jun 17.

PMID:
24939876
[PubMed - indexed for MEDLINE]
19.

Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation.

Lorincz MC, Schübeler D, Groudine M.

Mol Cell Biol. 2001 Dec;21(23):7913-22.

PMID:
11689684
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo.

Snowden AW, Gregory PD, Case CC, Pabo CO.

Curr Biol. 2002 Dec 23;12(24):2159-66.

PMID:
12498693
[PubMed - indexed for MEDLINE]

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