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Results: 1 to 20 of 74

1.

53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma.

Jankovic M, Feldhahn N, Oliveira TY, Silva IT, Kieffer-Kwon KR, Yamane A, Resch W, Klein I, Robbiani DF, Casellas R, Nussenzweig MC.

Mol Cell. 2013 Feb 21;49(4):623-31. doi: 10.1016/j.molcel.2012.11.029. Epub 2013 Jan 3.

PMID:
23290917
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements.

Oliveira TY, Resch W, Jankovic M, Casellas R, Nussenzweig MC, Klein IA.

J Immunol Methods. 2012 Jan 31;375(1-2):176-81. doi: 10.1016/j.jim.2011.10.007. Epub 2011 Oct 18.

PMID:
22033343
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.

Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC.

Mol Cell. 2009 Nov 25;36(4):631-41. doi: 10.1016/j.molcel.2009.11.007.

PMID:
19941823
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of the translocation partner in protection against AID-dependent chromosomal translocations.

Jankovic M, Robbiani DF, Dorsett Y, Eisenreich T, Xu Y, Tarakhovsky A, Nussenzweig A, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):187-92. doi: 10.1073/pnas.0908946107. Epub 2009 Dec 4.

PMID:
19966290
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.

Morales JC, Franco S, Murphy MM, Bassing CH, Mills KD, Adams MM, Walsh NC, Manis JP, Rassidakis GZ, Alt FW, Carpenter PB.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3310-5. Epub 2006 Feb 21.

PMID:
16492765
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.

FitzGerald J, Moureau S, Drogaris P, O'Connell E, Abshiru N, Verreault A, Thibault P, Grenon M, Lowndes NF.

PLoS One. 2011 Feb 24;6(2):e14714. doi: 10.1371/journal.pone.0014714.

PMID:
21383990
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC.

Cell. 2011 Sep 30;147(1):95-106. doi: 10.1016/j.cell.2011.07.048.

PMID:
21962510
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice.

Kotani A, Kakazu N, Tsuruyama T, Okazaki IM, Muramatsu M, Kinoshita K, Nagaoka H, Yabe D, Honjo T.

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1616-20. Epub 2007 Jan 24.

PMID:
17251349
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

Middendorp S, Xiao Y, Song JY, Peperzak V, Krijger PH, Jacobs H, Borst J.

Blood. 2009 Sep 10;114(11):2280-9. doi: 10.1182/blood-2009-03-208215. Epub 2009 Jul 16.

PMID:
19608748
[PubMed - indexed for MEDLINE]
Free Article
10.

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC.

Nature. 2006 Mar 2;440(7080):105-9. Epub 2006 Jan 8.

PMID:
16400328
[PubMed - indexed for MEDLINE]
11.

The role of activation-induced cytidine deaminase in lymphomagenesis.

Gu X, Shivarov V, Strout MP.

Curr Opin Hematol. 2012 Jul;19(4):292-8. doi: 10.1097/MOH.0b013e328353da3a. Review.

PMID:
22517589
[PubMed - indexed for MEDLINE]
12.

AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice.

Nepal RM, Zaheen A, Basit W, Li L, Berger SA, Martin A.

Oncogene. 2008 Aug 7;27(34):4752-6. doi: 10.1038/onc.2008.111. Epub 2008 Apr 14.

PMID:
18408759
[PubMed - indexed for MEDLINE]
13.

Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.

Robbiani DF, Nussenzweig MC.

Annu Rev Pathol. 2013 Jan 24;8:79-103. doi: 10.1146/annurev-pathol-020712-164004. Epub 2012 Sep 4. Review.

PMID:
22974238
[PubMed - indexed for MEDLINE]
14.

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.

Bothmer A, Robbiani DF, Feldhahn N, Gazumyan A, Nussenzweig A, Nussenzweig MC.

J Exp Med. 2010 Apr 12;207(4):855-65. doi: 10.1084/jem.20100244. Epub 2010 Apr 5.

PMID:
20368578
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.

Ward IM, Minn K, van Deursen J, Chen J.

Mol Cell Biol. 2003 Apr;23(7):2556-63.

PMID:
12640136
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.

Ruiz JF, Gómez-González B, Aguilera A.

PLoS Genet. 2011 Feb;7(2):e1002009. doi: 10.1371/journal.pgen.1002009. Epub 2011 Feb 24.

PMID:
21383964
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations.

Akasaka T, Muramatsu M, Kadowaki N, Ohno H, Ishizaki K, Yamabe H, Fukuhara S, Okuma M.

Jpn J Cancer Res. 1996 Sep;87(9):930-7.

PMID:
8878455
[PubMed - indexed for MEDLINE]
18.

The double-edged sword of activation-induced cytidine deaminase.

Wu X, Geraldes P, Platt JL, Cascalho M.

J Immunol. 2005 Jan 15;174(2):934-41.

PMID:
15634916
[PubMed - indexed for MEDLINE]
Free Article
19.

Role of 53BP1 oligomerization in regulating double-strand break repair.

Lottersberger F, Bothmer A, Robbiani DF, Nussenzweig MC, de Lange T.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2146-51. doi: 10.1073/pnas.1222617110. Epub 2013 Jan 23.

PMID:
23345425
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice.

Ward IM, Difilippantonio S, Minn K, Mueller MD, Molina JR, Yu X, Frisk CS, Ried T, Nussenzweig A, Chen J.

Mol Cell Biol. 2005 Nov;25(22):10079-86.

PMID:
16260621
[PubMed - indexed for MEDLINE]
Free PMC Article
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