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Items: 1 to 20 of 113

1.

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

Hancock DB, Soler Artigas M, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gläser S, Marchini J, Kraft P, Wareham NJ, Völzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ.

PLoS Genet. 2012;8(12):e1003098. doi: 10.1371/journal.pgen.1003098. Epub 2012 Dec 20.

2.

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Soler Artigas M, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD, Stricker BH.

Am J Respir Crit Care Med. 2012 Oct 1;186(7):622-32. doi: 10.1164/rccm.201202-0366OC. Epub 2012 Jul 26.

3.

Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.

Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER.

J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. doi: 10.1016/j.jaci.2013.01.051. Epub 2013 Mar 28.

4.

A genome-wide association study of pulmonary function measures in the Framingham Heart Study.

Wilk JB, Chen TH, Gottlieb DJ, Walter RE, Nagle MW, Brandler BJ, Myers RH, Borecki IB, Silverman EK, Weiss ST, O'Connor GT.

PLoS Genet. 2009 Mar;5(3):e1000429. doi: 10.1371/journal.pgen.1000429. Epub 2009 Mar 20.

5.

IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function.

Sadeghnejad A, Meyers DA, Bottai M, Sterling DA, Bleecker ER, Ohar JA.

Am J Respir Crit Care Med. 2007 Oct 15;176(8):748-52. Epub 2007 Jul 5.

PMID:
17615386
6.

Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.

Zhou H, Yang J, Li D, Xiao J, Wang B, Wang L, Ma C, Xu S, Ou X, Feng Y.

J Hum Genet. 2012 Nov 26;57(11):738-46. doi: 10.1038/jhg.2012.104. Epub 2012 Aug 23.

PMID:
22914670
7.

Genome-wide association study identifies five loci associated with lung function.

Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle WL, Rudnicka AR; Wellcome Trust Case Control Consortium, Barroso I, Loos RJ, Wareham NJ, Mustelin L, Rantanen T, Surakka I, Imboden M, Wichmann HE, Grkovic I, Jankovic S, Zgaga L, Hartikainen AL, Peltonen L, Gyllensten U, Johansson A, Zaboli G, Campbell H, Wild SH, Wilson JF, Gläser S, Homuth G, Völzke H, Mangino M, Soranzo N, Spector TD, Polasek O, Rudan I, Wright AF, Heliövaara M, Ripatti S, Pouta A, Naluai AT, Olin AC, Torén K, Cooper MN, James AL, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Smith GD, Ebrahim S, McKeever TM, Pavord ID, MacLeod AK, Morris AD, Porteous DJ, Cooper C, Dennison E, Shaheen S, Karrasch S, Schnabel E, Schulz H, Grallert H, Bouatia-Naji N, Delplanque J, Froguel P, Blakey JD; NSHD Respiratory Study Team, Britton JR, Morris RW, Holloway JW, Lawlor DA, Hui J, Nyberg F, Jarvelin MR, Jackson C, Kähönen M, Kaprio J, Probst-Hensch NM, Koch B, Hayward C, Evans DM, Elliott P, Strachan DP, Hall IP, Tobin MD.

Nat Genet. 2010 Jan;42(1):36-44. doi: 10.1038/ng.501. Epub 2009 Dec 13.

8.

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

Obeidat M, Wain LV, Shrine N, Kalsheker N, Soler Artigas M, Repapi E, Burton PR, Johnson T, Ramasamy A, Zhao JH, Zhai G, Huffman JE, Vitart V, Albrecht E, Igl W, Hartikainen AL, Pouta A, Cadby G, Hui J, Palmer LJ, Hadley D, McArdle WL, Rudnicka AR, Barroso I, Loos RJ, Wareham NJ, Mangino M, Soranzo N, Spector TD, Gläser S, Homuth G, Völzke H, Deloukas P, Granell R, Henderson J, Grkovic I, Jankovic S, Zgaga L, Polašek O, Rudan I, Wright AF, Campbell H, Wild SH, Wilson JF, Heinrich J, Imboden M, Probst-Hensch NM, Gyllensten U, Johansson Å, Zaboli G, Mustelin L, Rantanen T, Surakka I, Kaprio J, Jarvelin MR, Hayward C, Evans DM, Koch B, Musk AW, Elliott P, Strachan DP, Tobin MD, Sayers I, Hall IP; SpiroMeta Consortium.

PLoS One. 2011;6(5):e19382. doi: 10.1371/journal.pone.0019382. Epub 2011 May 20.

9.

Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung function.

Tang W, Bentley AR, Kritchevsky SB, Harris TB, Newman AB, Bauer DC, Meibohm B, Cassano PA; Health ABC study.

Free Radic Biol Med. 2013 Oct;63:304-12. doi: 10.1016/j.freeradbiomed.2013.05.016. Epub 2013 May 17.

10.

Genome-wide association studies identify locus on 6p21 influencing lung function in the Korean population.

Kim WJ, Lee MK, Shin C, Cho NH, Lee SD, Oh YM, Sung J.

Respirology. 2014 Apr;19(3):360-8. doi: 10.1111/resp.12230. Epub 2014 Jan 6.

11.

Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes.

Masuko H, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N.

Int J Chron Obstruct Pulmon Dis. 2011;6:181-9. doi: 10.2147/COPD.S16383. Epub 2011 Mar 2.

12.

Identification of FAM13A gene associated with the ratio of FEV1 to FVC in Korean population by genome-wide association studies including gene-environment interactions.

Kim S, Kim H, Cho N, Lee SK, Han BG, Sull JW, Jee SH, Shin C.

J Hum Genet. 2015 Mar;60(3):139-45. doi: 10.1038/jhg.2014.118. Epub 2015 Jan 22.

PMID:
25608829
13.

Admixture mapping identifies a quantitative trait locus associated with FEV1/FVC in the COPDGene Study.

Parker MM, Foreman MG, Abel HJ, Mathias RA, Hetmanski JB, Crapo JD, Silverman EK, Beaty TH; COPDGene Investigators.

Genet Epidemiol. 2014 Nov;38(7):652-9. doi: 10.1002/gepi.21847. Epub 2014 Aug 11.

14.

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BH, O'Connor GT, London SJ.

Nat Genet. 2010 Jan;42(1):45-52. doi: 10.1038/ng.500. Epub 2009 Dec 13.

15.

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.

Pillai SG, Kong X, Edwards LD, Cho MH, Anderson WH, Coxson HO, Lomas DA, Silverman EK; ECLIPSE and ICGN Investigators.

Am J Respir Crit Care Med. 2010 Dec 15;182(12):1498-505. doi: 10.1164/rccm.201002-0151OC. Epub 2010 Jul 23.

16.

Framingham Heart Study genome-wide association: results for pulmonary function measures.

Wilk JB, Walter RE, Laramie JM, Gottlieb DJ, O'Connor GT.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S8.

17.

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.

Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH, Albrecht E, Dominiczak AF, Kerr SM, Smith BH, Cadby G, Hui J, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Ebrahim S, Smith GD, Barroso I, Loos RJ, Wareham NJ, Cooper C, Dennison E, Shaheen SO, Liu JZ, Marchini J; Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, Dahgam S, Naluai AT, Olin AC, Karrasch S, Heinrich J, Schulz H, McKeever TM, Pavord ID, Heliövaara M, Ripatti S, Surakka I, Blakey JD, Kähönen M, Britton JR, Nyberg F, Holloway JW, Lawlor DA, Morris RW, James AL, Jackson CM, Hall IP, Tobin MD; SpiroMeta Consortium.

Am J Respir Crit Care Med. 2011 Oct 1;184(7):786-95. doi: 10.1164/rccm.201102-0192OC.

18.

Longevity-associated mitochondrial DNA 5178 C/A polymorphism and its interaction with cigarette consumption are associated with pulmonary function in middle-aged Japanese men.

Kokaze A, Ishikawa M, Matsunaga N, Yoshida M, Satoh M, Teruya K, Honmyo R, Shirasawa T, Hoshino H, Takashima Y.

J Hum Genet. 2007;52(8):680-5. Epub 2007 Jul 17.

PMID:
17636359
19.

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ.

Nat Genet. 2014 Jul;46(7):669-77. doi: 10.1038/ng.3011. Epub 2014 Jun 15.

20.

Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function.

Wilk JB, Herbert A, Shoemaker CM, Gottlieb DJ, Karamohamed S.

Am J Respir Crit Care Med. 2007 Mar 15;175(6):554-60. Epub 2007 Jan 4.

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