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Results: 1 to 20 of 108

1.

Polymorphisms of the core, NS3, and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma.

El-Shamy A, Shindo M, Shoji I, Deng L, Okuno T, Hotta H.

Hepatology. 2013 Aug;58(2):555-63. doi: 10.1002/hep.26205. Epub 2013 Jun 14.

PMID:
23281009
[PubMed - indexed for MEDLINE]
2.

Polymorphisms of hepatitis C virus non-structural protein 5A and core protein and clinical outcome of pegylated-interferon/ribavirin combination therapy.

El-Shamy A, Kim SR, Ide YH, Sasase N, Imoto S, Deng L, Shoji I, Hotta H.

Intervirology. 2012;55(1):1-11. doi: 10.1159/000322219. Epub 2011 Feb 4.

PMID:
21293098
[PubMed - indexed for MEDLINE]
3.

Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy.

Kumthip K, Pantip C, Chusri P, Thongsawat S, O'Brien A, Nelson KE, Maneekarn N.

J Viral Hepat. 2011 Apr;18(4):e117-25. doi: 10.1111/j.1365-2893.2010.01379.x. Epub 2010 Oct 19.

PMID:
20955493
[PubMed - indexed for MEDLINE]
4.

Risk of hepatocellular carcinoma and secondary structure of hepatitis C virus (HCV) NS3 protein amino-terminus, in patients infected with HCV subtype 1b.

Nishise Y, Saito T, Sugahara K, Ito JI, Saito K, Togashi H, Nagano-Fujii M, Hotta H, Kawata S.

J Infect Dis. 2007 Oct 1;196(7):1006-9. Epub 2007 Aug 23.

PMID:
17763321
[PubMed - indexed for MEDLINE]
Free Article
5.

Sequence heterogeneity in NS5A of hepatitis C virus genotypes 2a and 2b and clinical outcome of pegylated-interferon/ribavirin therapy.

El-Shamy A, Shoji I, Kim SR, Ide Y, Imoto S, Deng L, Yoon S, Fujisawa T, Tani S, Yano Y, Seo Y, Azuma T, Hotta H.

PLoS One. 2012;7(2):e30513. doi: 10.1371/journal.pone.0030513. Epub 2012 Feb 2.

PMID:
22319571
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Hepatitis C virus 1b viral factors (core, NS3, and NS5A) and increased risk of hepatocellular carcinoma.

Sharma SD.

Hepatology. 2013 Aug;58(2):491-3. doi: 10.1002/hep.26362. Epub 2013 Jun 25. No abstract available.

PMID:
23471816
[PubMed - indexed for MEDLINE]
7.

Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to pegylated-interferon/ribavirin combination therapy.

El-Shamy A, Shoji I, Saito T, Watanabe H, Ide YH, Deng L, Kawata S, Hotta H.

Microbiol Immunol. 2011 Jun;55(6):418-26. doi: 10.1111/j.1348-0421.2011.00331.x.

PMID:
21371092
[PubMed - indexed for MEDLINE]
8.

Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy.

Akuta N, Suzuki F, Hirakawa M, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H.

J Med Virol. 2011 Jun;83(6):1016-22. doi: 10.1002/jmv.22094.

PMID:
21503914
[PubMed - indexed for MEDLINE]
9.

Amino acid substitutions in the hepatitis C Virus core region and lipid metabolism are associated with hepatocarcinogenesis in nonresponders to interferon plus ribavirin combination therapy.

Seko Y, Akuta N, Suzuki F, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H.

Intervirology. 2013;56(1):13-21. doi: 10.1159/000339993. Epub 2012 Aug 16.

PMID:
22907167
[PubMed - indexed for MEDLINE]
10.

Hepatitis C virus genotype 1b increases cumulative lifetime risk of hepatocellular carcinoma.

Lee MH, Yang HI, Lu SN, Jen CL, You SL, Wang LY, L'Italien G, Chen CJ, Yuan Y; REVEAL-HCV Study Group.

Int J Cancer. 2014 Sep 1;135(5):1119-26. doi: 10.1002/ijc.28753. Epub 2014 Feb 14.

PMID:
24482200
[PubMed - indexed for MEDLINE]
11.

Virological and biochemical features in elderly HCV patients with hepatocellular carcinoma: amino acid substitutions in HCV core region as predictor of mortality after first treatment.

Ogura S, Akuta N, Hirakawa M, Kawamura Y, Yatsuji H, Sezaki H, Hosaka T, Kobayashi M, Suzuki F, Suzuki Y, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H.

Intervirology. 2009;52(4):179-88. doi: 10.1159/000225193. Epub 2009 Jun 17.

PMID:
19546575
[PubMed - indexed for MEDLINE]
12.

High amino acid variability within the NS5A of hepatitis C virus (HCV) is associated with hepatocellular carcinoma in patients with HCV-1b-related cirrhosis.

Giménez-Barcons M, Franco S, Suárez Y, Forns X, Ampurdanès S, Puig-Basagoiti F, Sánchez-Fueyo A, Barrera JM, Llovet JM, Bruix J, Sánchez-Tapias JM, Rodés J, Saiz JC.

Hepatology. 2001 Jul;34(1):158-67.

PMID:
11431747
[PubMed - indexed for MEDLINE]
13.

Identification of hepatitis C virus (HCV) subtype 1b strains that are highly, or only weakly, associated with hepatocellular carcinoma on the basis of the secondary structure of an amino-terminal portion of the HCV NS3 protein.

Ogata S, Florese RH, Nagano-Fujii M, Hidajat R, Deng L, Ku Y, Yoon S, Saito T, Kawata S, Hotta H.

J Clin Microbiol. 2003 Jul;41(7):2835-41.

PMID:
12843009
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evolution of hepatitis C virus non-structural 5A gene in the progression of liver disease to hepatocellular carcinoma.

De Mitri MS, Cassini R, Bagaglio S, Morsica G, Andreone P, Marino N, Bernardi M.

Liver Int. 2007 Oct;27(8):1126-33.

PMID:
17845542
[PubMed - indexed for MEDLINE]
15.
16.

Interferon resistance of hepatitis C virus genotype 1b: relationship to nonstructural 5A gene quasispecies mutations.

Pawlotsky JM, Germanidis G, Neumann AU, Pellerin M, Frainais PO, Dhumeaux D.

J Virol. 1998 Apr;72(4):2795-805.

PMID:
9525599
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Deep-sequencing analysis of the association between the quasispecies nature of the hepatitis C virus core region and disease progression.

Miura M, Maekawa S, Takano S, Komatsu N, Tatsumi A, Asakawa Y, Shindo K, Amemiya F, Nakayama Y, Inoue T, Sakamoto M, Yamashita A, Moriishi K, Enomoto N.

J Virol. 2013 Dec;87(23):12541-51. doi: 10.1128/JVI.00826-13. Epub 2013 Aug 14.

PMID:
23946458
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma.

Akuta N, Suzuki F, Kawamura Y, Yatsuji H, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Arase Y, Ikeda K, Kumada H.

J Med Virol. 2008 Aug;80(8):1354-62. doi: 10.1002/jmv.21202.

PMID:
18551609
[PubMed - indexed for MEDLINE]
19.

Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis.

Akuta N, Suzuki F, Seko Y, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Hara T, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H.

Hepatology. 2012 Dec;56(6):2134-41. doi: 10.1002/hep.25949.

PMID:
22806754
[PubMed - indexed for MEDLINE]
20.

Epidemic spread of hepatitis C virus genotype 3a and relation to high incidence of hepatocellular carcinoma in Pakistan.

Khan A, Tanaka Y, Azam Z, Abbas Z, Kurbanov F, Saleem U, Hamid S, Jafri W, Mizokami M.

J Med Virol. 2009 Jul;81(7):1189-97. doi: 10.1002/jmv.21466.

PMID:
19475617
[PubMed - indexed for MEDLINE]

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