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Results: 1 to 20 of 124

1.

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses.

Xu YQ, Long L, Yan JQ, Wei L, Pan MQ, Gao HM, Zhou P, Liu M, Zhu CS, Tang BS, Wang Q.

CNS Neurosci Ther. 2013 Mar;19(3):170-7. doi: 10.1111/cns.12053. Epub 2012 Dec 28.

PMID:
23279934
[PubMed - indexed for MEDLINE]
2.

Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.

Yan J, Xu Y, Zhu C, Zhang L, Wu A, Yang Y, Xiong Z, Deng C, Huang XF, Yenari MA, Yang YG, Ying W, Wang Q.

PLoS One. 2011;6(6):e20945. doi: 10.1371/journal.pone.0020945. Epub 2011 Jun 22.

PMID:
21731633
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway.

Tiong CX, Lu M, Bian JS.

Br J Pharmacol. 2010 Sep;161(2):467-80. doi: 10.1111/j.1476-5381.2010.00887.x. Erratum in: Br J Pharmacol. 2013 Apr;168(8):2011-2.

PMID:
20735429
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Neurotrophin-3 reduces apoptosis induced by 6-OHDA in PC12 cells through Akt signaling pathway.

Li Z, Hu Y, Zhu Q, Zhu J.

Int J Dev Neurosci. 2008 Oct;26(6):635-40. doi: 10.1016/j.ijdevneu.2008.03.009. Epub 2008 Apr 4.

PMID:
18462913
[PubMed - indexed for MEDLINE]
5.

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.

Kumar A, Sharma N, Gupta A, Kalonia H, Mishra J.

Brain Res. 2012 Aug 30;1471:13-22. doi: 10.1016/j.brainres.2012.06.050. Epub 2012 Jul 10.

PMID:
22789904
[PubMed - indexed for MEDLINE]
6.

Neuroprotection by marine-derived compound, 11-dehydrosinulariolide, in an in vitro Parkinson's model: a promising candidate for the treatment of Parkinson's disease.

Chen WF, Chakraborty C, Sung CS, Feng CW, Jean YH, Lin YY, Hung HC, Huang TY, Huang SY, Su TM, Sung PJ, Sheu JH, Wen ZH.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Mar;385(3):265-75. doi: 10.1007/s00210-011-0710-2. Epub 2011 Nov 27.

PMID:
22119889
[PubMed - indexed for MEDLINE]
7.

Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Chong CM, Zhou ZY, Razmovski-Naumovski V, Cui GZ, Zhang LQ, Sa F, Hoi PM, Chan K, Lee SM.

Neurosci Lett. 2013 May 24;543:121-5. doi: 10.1016/j.neulet.2013.02.069. Epub 2013 Apr 3.

PMID:
23562886
[PubMed - indexed for MEDLINE]
8.

Isoliquiritigenin isolated from licorice Glycyrrhiza uralensis prevents 6-hydroxydopamine-induced apoptosis in dopaminergic neurons.

Hwang CK, Chun HS.

Biosci Biotechnol Biochem. 2012;76(3):536-43.

PMID:
22451397
[PubMed - indexed for MEDLINE]
Free Article
9.

Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats.

Lee EY, Lee JE, Park JH, Shin IC, Koh HC.

Toxicol Lett. 2012 Sep 18;213(3):332-44. doi: 10.1016/j.toxlet.2012.07.016. Epub 2012 Jul 27.

PMID:
22842585
[PubMed - indexed for MEDLINE]
10.

Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway.

Fujita H, Ogino T, Kobuchi H, Fujiwara T, Yano H, Akiyama J, Utsumi K, Sasaki J.

Brain Res. 2006 Oct 3;1113(1):10-23. Epub 2006 Aug 30.

PMID:
16945353
[PubMed - indexed for MEDLINE]
11.

Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways.

Zhang Z, Cui W, Li G, Yuan S, Xu D, Hoi MP, Lin Z, Dou J, Han Y, Lee SM.

J Agric Food Chem. 2012 Aug 22;60(33):8171-82. doi: 10.1021/jf301511m. Epub 2012 Aug 9.

PMID:
22838648
[PubMed - indexed for MEDLINE]
12.

Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death.

Lou H, Fan P, Perez RG, Lou H.

Bioorg Med Chem. 2011 Jul 1;19(13):4021-7. doi: 10.1016/j.bmc.2011.05.021. Epub 2011 May 19.

PMID:
21652214
[PubMed - indexed for MEDLINE]
13.

Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death.

Chen G, Bower KA, Ma C, Fang S, Thiele CJ, Luo J.

FASEB J. 2004 Jul;18(10):1162-4. Epub 2004 May 7.

PMID:
15132987
[PubMed - indexed for MEDLINE]
Free Article
14.

Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway.

Gao Y, Dong C, Yin J, Shen J, Tian J, Li C.

Cell Mol Neurobiol. 2012 May;32(4):523-9. doi: 10.1007/s10571-011-9792-0. Epub 2012 Jan 6.

PMID:
22222440
[PubMed - indexed for MEDLINE]
15.

Neuroprotection by urate on 6-OHDA-lesioned rat model of Parkinson's disease: linking to Akt/GSK3β signaling pathway.

Gong L, Zhang QL, Zhang N, Hua WY, Huang YX, Di PW, Huang T, Xu XS, Liu CF, Hu LF, Luo WF.

J Neurochem. 2012 Dec;123(5):876-85. doi: 10.1111/jnc.12038. Epub 2012 Oct 25.

PMID:
23094836
[PubMed - indexed for MEDLINE]
16.

Erythropoietin protects PC12 cells from beta-amyloid(25-35)-induced apoptosis via PI3K/Akt signaling pathway.

Ma R, Xiong N, Huang C, Tang Q, Hu B, Xiang J, Li G.

Neuropharmacology. 2009 May-Jun;56(6-7):1027-34. doi: 10.1016/j.neuropharm.2009.02.006. Epub 2009 Mar 4.

PMID:
19268480
[PubMed - indexed for MEDLINE]
17.

Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk.

Xiao H, Lv F, Xu W, Zhang L, Jing P, Cao X.

Toxicology. 2011 Dec 18;290(2-3):286-94. doi: 10.1016/j.tox.2011.10.007. Epub 2011 Oct 15.

PMID:
22019741
[PubMed - indexed for MEDLINE]
18.

Ethanolic extract of fructus Alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Zhang ZJ, Cheang LC, Wang MW, Li GH, Chu IK, Lin ZX, Lee SM.

Cell Mol Neurobiol. 2012 Jan;32(1):27-40. doi: 10.1007/s10571-011-9731-0. Epub 2011 Jul 9.

PMID:
21744117
[PubMed - indexed for MEDLINE]
19.

Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3.

Koh SH, Kim SH, Kwon H, Park Y, Kim KS, Song CW, Kim J, Kim MH, Yu HJ, Henkel JS, Jung HK.

Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):72-81.

PMID:
14559356
[PubMed - indexed for MEDLINE]
20.

Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation.

Ha KS, Kim KM, Kwon YG, Bai SK, Nam WD, Yoo YM, Kim PK, Chung HT, Billiar TR, Kim YM.

FASEB J. 2003 Jun;17(9):1036-47.

PMID:
12773486
[PubMed - indexed for MEDLINE]
Free Article

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