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Results: 1 to 20 of 111

1.

Synthesis and biological activity of 25-hydroxy-2-methylene-vitamin D3 compounds.

Sibilska I, Sicinski RR, Plum LA, DeLuca HF.

J Steroid Biochem Mol Biol. 2013 Jul;136:17-22. doi: 10.1016/j.jsbmb.2012.12.012. Epub 2012 Dec 27. Review.

PMID:
23274116
[PubMed - indexed for MEDLINE]
2.

1-desoxy analog of 2MD: synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3.

Sibilska I, Barycka KM, Sicinski RR, Plum LA, Deluca HF.

J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):51-5. doi: 10.1016/j.jsbmb.2010.03.063. Epub 2010 Mar 27.

PMID:
20347975
[PubMed - indexed for MEDLINE]
3.

Highly potent 2-methylene analogs of 1α,25-dihydroxyvitamin D3: synthesis and biological evaluation.

Sibilska IK, Szybinski M, Sicinski RR, Plum LA, Deluca HF.

J Steroid Biochem Mol Biol. 2013 Jul;136:9-13. doi: 10.1016/j.jsbmb.2013.02.001. Epub 2013 Feb 11. Review.

PMID:
23410597
[PubMed - indexed for MEDLINE]
4.

Synthesis of novel 19-norvitamin D3 analogs with unnatural triene system.

Kulesza U, Mouriño A, Plum LA, Deluca HF, Sicinski RR.

J Steroid Biochem Mol Biol. 2013 Jul;136:23-6. doi: 10.1016/j.jsbmb.2012.12.008. Epub 2012 Dec 25. Review.

PMID:
23270753
[PubMed - indexed for MEDLINE]
5.

Synthesis and biological evaluation of novel 6-substituted analogs of 1α,25-dihydroxy-19-norvitamin D3.

Sokolowska K, Sicinski RR, Mouriño A, Plum LA, DeLuca HF.

J Steroid Biochem Mol Biol. 2013 Jul;136:30-3. doi: 10.1016/j.jsbmb.2012.10.016. Epub 2012 Oct 30. Review.

PMID:
23116698
[PubMed - indexed for MEDLINE]
6.

New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.

Sicinski RR, Prahl JM, Smith CM, DeLuca HF.

J Med Chem. 1998 Nov 5;41(23):4662-74.

PMID:
9804706
[PubMed - indexed for MEDLINE]
7.

13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D₃ (2MD): total synthesis, docking to the VDR, and biological evaluation.

Plonska-Ocypa K, Sibilska I, Sicinski RR, Sicinska W, Plum LA, DeLuca HF.

Bioorg Med Chem. 2011 Dec 1;19(23):7205-20. doi: 10.1016/j.bmc.2011.09.048. Epub 2011 Oct 2.

PMID:
22018918
[PubMed - indexed for MEDLINE]
8.

Ring-A-seco analogs of 1α,25-dihydroxy-19-norvitamin D3.

Glebocka A, Sicinski RR, Plum LA, Deluca HF.

J Steroid Biochem Mol Biol. 2013 Jul;136:39-43. doi: 10.1016/j.jsbmb.2012.09.030. Epub 2012 Oct 9. Review.

PMID:
23064199
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.

Plonska-Ocypa K, Sicinski RR, Plum LA, Grzywacz P, Frelek J, Clagett-Dame M, DeLuca HF.

Bioorg Med Chem. 2009 Feb 15;17(4):1747-63. doi: 10.1016/j.bmc.2008.11.082. Epub 2008 Dec 10.

PMID:
19167893
[PubMed - indexed for MEDLINE]
10.

Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.

Shimazaki M, Miyamoto Y, Yamamoto K, Yamada S, Takami M, Shinki T, Udagawa N, Shimizu M.

Bioorg Med Chem. 2006 Jul 1;14(13):4645-56. Epub 2006 Mar 2.

PMID:
16513359
[PubMed - indexed for MEDLINE]
11.

2-Ethyl and 2-ethylidene analogues of 1alpha,25-dihydroxy-19-norvitamin D(3): synthesis, conformational analysis, biological activities, and docking to the modeled rVDR ligand binding domain.

Sicinski RR, Rotkiewicz P, Kolinski A, Sicinska W, Prahl JM, Smith CM, DeLuca HF.

J Med Chem. 2002 Aug 1;45(16):3366-80.

PMID:
12139448
[PubMed - indexed for MEDLINE]
12.

New highly calcemic 1 alpha,25-dihydroxy-19-norvitamin D(3) compounds with modified side chain: 26,27-dihomo- and 26,27-dimethylene analogs in 20S-series.

Sicinski RR, Prahl JM, Smith CM, DeLuca HF.

Steroids. 2002 Mar;67(3-4):247-56.

PMID:
11856548
[PubMed - indexed for MEDLINE]
13.

New derivative of 1alpha,25-dihydroxy-19-norvitamin D3 with 3'-alkoxypropylidene moiety at C-2: synthesis, biological activity and conformational analysis.

Glebocka A, Sicinski RR, DeLuca HF.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):25-30.

PMID:
15225741
[PubMed - indexed for MEDLINE]
14.

2-(3'-Hydroxypropylidene)-1alpha-hydroxy-19-norvitamin D compounds with truncated side chains.

Glebocka A, Sicinski RR, Plum LA, DeLuca HF.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):310-5. Epub 2007 Jan 16.

PMID:
17223340
[PubMed - indexed for MEDLINE]
15.

Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.

Shimizu M, Miyamoto Y, Kobayashi E, Shimazaki M, Yamamoto K, Reischl W, Yamada S.

Bioorg Med Chem. 2006 Jun 15;14(12):4277-94. Epub 2006 Feb 24.

PMID:
16503143
[PubMed - indexed for MEDLINE]
16.

Synthesis and Biological Activity of 25-Hydroxy-2-methylene-vitamin D3 Analogues Monohydroxylated in the A-ring.

Sibilska IK, Sicinski RR, Ochalek JT, Plum LA, Deluca HF.

J Med Chem. 2014 Sep 15. [Epub ahead of print]

PMID:
25221942
[PubMed - as supplied by publisher]
17.

2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor.

Grzywacz P, Plum LA, Sicinska W, Sicinski RR, Prahl JM, DeLuca HF.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):13-7.

PMID:
15225739
[PubMed - indexed for MEDLINE]
18.

New derivatives of 1alpha,25-dihydroxy-19-norvitamin D3 with two substituents at C-2: synthesis and biological activity.

Shimizu M, Iwasaki Y, Shimazaki M, Amano Y, Yamamoto K, Reischl W, Yamada S.

Bioorg Med Chem Lett. 2005 Mar 1;15(5):1451-5.

PMID:
15713405
[PubMed - indexed for MEDLINE]
19.

New 1alpha,25-dihydroxy-19-norvitamin D3 analogs with a frozen A-ring conformation.

Glebocka A, Sicinski RR, Plum LA, DeLuca HF.

J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):46-50. doi: 10.1016/j.jsbmb.2010.03.011. Epub 2010 Mar 7.

PMID:
20214980
[PubMed - indexed for MEDLINE]
20.

Synthesis and biological activity of 1 alpha, 25-dihydroxy-18-norvitamin D3 and 1 alpha, 25-dihydroxy-18,19-dinorvitamin D3.

Sicinski RR, Perlman KL, Prahl J, Smith C, DeLuca HF.

J Med Chem. 1996 Oct 25;39(22):4497-506.

PMID:
8893845
[PubMed - indexed for MEDLINE]

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