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Items: 1 to 20 of 91

1.

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors.

Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schöneberg T, Schaefer M, Krügel U, Smajilovic S, Bräuner-Osborne H, Baerwald C, Wagner U.

Nat Commun. 2012;3:1329. doi: 10.1038/ncomms2339.

2.

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, Germain RN, Kastner DL, Chae JJ.

Nature. 2012 Dec 6;492(7427):123-7. doi: 10.1038/nature11588. Epub 2012 Nov 11.

3.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

4.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099. Epub 2010 Nov 3.

5.

Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome.

Vyleta ML, Wong J, Magun BE.

PLoS One. 2012;7(5):e36044. doi: 10.1371/journal.pone.0036044. Epub 2012 May 14.

6.

Histones trigger sterile inflammation by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Tschopp J, Anders HJ.

Eur J Immunol. 2013 Dec;43(12):3336-42. doi: 10.1002/eji.201243224. Epub 2013 Sep 6.

7.

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.

Bracey NA, Beck PL, Muruve DA, Hirota SA, Guo J, Jabagi H, Wright JR Jr, Macdonald JA, Lees-Miller JP, Roach D, Semeniuk LM, Duff HJ.

Exp Physiol. 2013 Feb;98(2):462-72. doi: 10.1113/expphysiol.2012.068338. Epub 2012 Jul 30.

8.

Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome.

Ito M, Yanagi Y, Ichinohe T.

PLoS Pathog. 2012;8(8):e1002857. doi: 10.1371/journal.ppat.1002857. Epub 2012 Aug 9.

9.

Critical role for the NLRP3 inflammasome during acute lung injury.

Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA.

J Immunol. 2014 Jun 15;192(12):5974-83. doi: 10.4049/jimmunol.1400368. Epub 2014 May 2.

10.

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P.

Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22.

PMID:
24952504
11.

K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling.

Katsnelson MA, Rucker LG, Russo HM, Dubyak GR.

J Immunol. 2015 Apr 15;194(8):3937-52. doi: 10.4049/jimmunol.1402658. Epub 2015 Mar 11.

12.

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.

Luheshi NM, Giles JA, Lopez-Castejon G, Brough D.

Eur J Immunol. 2012 Mar;42(3):716-25. doi: 10.1002/eji.201142079. Epub 2011 Dec 27.

13.

Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex.

Nour AM, Reichelt M, Ku CC, Ho MY, Heineman TC, Arvin AM.

J Biol Chem. 2011 May 20;286(20):17921-33. doi: 10.1074/jbc.M110.210575. Epub 2011 Mar 8.

14.

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury.

Seo SU, Kamada N, Muñoz-Planillo R, Kim YG, Kim D, Koizumi Y, Hasegawa M, Himpsl SD, Browne HP, Lawley TD, Mobley HL, Inohara N, Núñez G.

Immunity. 2015 Apr 21;42(4):744-55. doi: 10.1016/j.immuni.2015.03.004. Epub 2015 Apr 7.

15.

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation.

Triantafilou K, Hughes TR, Triantafilou M, Morgan BP.

J Cell Sci. 2013 Jul 1;126(Pt 13):2903-13. doi: 10.1242/jcs.124388. Epub 2013 Apr 23.

16.

Basic calcium phosphate crystals induce monocyte/macrophage IL-1β secretion through the NLRP3 inflammasome in vitro.

Pazár B, Ea HK, Narayan S, Kolly L, Bagnoud N, Chobaz V, Roger T, Lioté F, So A, Busso N.

J Immunol. 2011 Feb 15;186(4):2495-502. doi: 10.4049/jimmunol.1001284. Epub 2011 Jan 14.

17.

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R.

Immunity. 2013 Jun 27;38(6):1154-63. doi: 10.1016/j.immuni.2013.05.015.

18.

Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages.

Kahlenberg JM, Carmona-Rivera C, Smith CK, Kaplan MJ.

J Immunol. 2013 Feb 1;190(3):1217-26. doi: 10.4049/jimmunol.1202388. Epub 2012 Dec 24.

19.

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome.

Sauter KA, Wood LJ, Wong J, Iordanov M, Magun BE.

Cancer Biol Ther. 2011 Jun 15;11(12):1008-16. Epub 2011 Jun 15.

20.

Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.

Kuipers MT, Aslami H, Janczy JR, van der Sluijs KF, Vlaar AP, Wolthuis EK, Choi G, Roelofs JJ, Flavell RA, Sutterwala FS, Bresser P, Leemans JC, van der Poll T, Schultz MJ, Wieland CW.

Anesthesiology. 2012 May;116(5):1104-15. doi: 10.1097/ALN.0b013e3182518bc0.

PMID:
22531249
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