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Items: 1 to 20 of 110


Mitochondrial permeability transition pore inhibitors prevent ethanol-induced neuronal death in mice.

Lamarche F, Carcenac C, Gonthier B, Cottet-Rousselle C, Chauvin C, Barret L, Leverve X, Savasta M, Fontaine E.

Chem Res Toxicol. 2013 Jan 18;26(1):78-88. doi: 10.1021/tx300395w. Epub 2013 Jan 7.


Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy.

Matas J, Young NT, Bourcier-Lucas C, Ascah A, Marcil M, Deschepper CF, Burelle Y.

J Mol Cell Cardiol. 2009 Mar;46(3):420-30. doi: 10.1016/j.yjmcc.2008.10.020. Epub 2008 Nov 6.


Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.

Dumas JF, Argaud L, Cottet-Rousselle C, Vial G, Gonzalez C, Detaille D, Leverve X, Fontaine E.

J Biol Chem. 2009 May 29;284(22):15117-25. doi: 10.1074/jbc.M900926200. Epub 2009 Apr 3.


Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death.

Devun F, Walter L, Belliere J, Cottet-Rousselle C, Leverve X, Fontaine E.

PLoS One. 2010 Jul 26;5(7):e11792. doi: 10.1371/journal.pone.0011792.


Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

El-Mir MY, Detaille D, R-Villanueva G, Delgado-Esteban M, Guigas B, Attia S, Fontaine E, Almeida A, Leverve X.

J Mol Neurosci. 2008;34(1):77-87. Epub 2007 Nov 27.


Effects of FK506 and cyclosporin a on calcium ionophore-induced mitochondrial depolarization and cytosolic calcium in astrocytes and neurons.

Kahraman S, Bambrick LL, Fiskum G.

J Neurosci Res. 2011 Dec;89(12):1973-8. doi: 10.1002/jnr.22709. Epub 2011 Jul 11.


The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes.

Reddy PV, Rao KV, Norenberg MD.

Lab Invest. 2008 Aug;88(8):816-30. doi: 10.1038/labinvest.2008.49. Epub 2008 Jun 30.


Protection of pancreatic INS-1 ╬▓-cells from glucose- and fructose-induced cell death by inhibiting mitochondrial permeability transition with cyclosporin A or metformin.

Lablanche S, Cottet-Rousselle C, Lamarche F, Benhamou PY, Halimi S, Leverve X, Fontaine E.

Cell Death Dis. 2011 Mar 24;2:e134. doi: 10.1038/cddis.2011.15.


Ethanol withdrawal provokes opening of the mitochondrial membrane permeability transition pore in an estrogen-preventable manner.

Jung ME, Wilson AM, Ju X, Wen Y, Metzger DB, Simpkins JW.

J Pharmacol Exp Ther. 2009 Mar;328(3):692-8. doi: 10.1124/jpet.108.146829. Epub 2008 Dec 2.


Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore.

Takuma K, Phuagphong P, Lee E, Mori K, Baba A, Matsuda T.

J Biol Chem. 2001 Dec 21;276(51):48093-9. Epub 2001 Oct 24.


The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria.

Azarashvili T, Grachev D, Krestinina O, Evtodienko Y, Yurkov I, Papadopoulos V, Reiser G.

Cell Calcium. 2007 Jul;42(1):27-39. Epub 2006 Dec 15.


Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition.

Greco T, Fiskum G.

J Bioenerg Biomembr. 2010 Dec;42(6):491-7. doi: 10.1007/s10863-010-9312-9.


Neuroglobin overexpression inhibits oxygen-glucose deprivation-induced mitochondrial permeability transition pore opening in primary cultured mouse cortical neurons.

Yu Z, Liu N, Li Y, Xu J, Wang X.

Neurobiol Dis. 2013 Aug;56:95-103. doi: 10.1016/j.nbd.2013.04.015. Epub 2013 Apr 29.


Prerequisites for ubiquinone analogs to prevent mitochondrial permeability transition-induced cell death.

Belliere J, Devun F, Cottet-Rousselle C, Batandier C, Leverve X, Fontaine E.

J Bioenerg Biomembr. 2012 Feb;44(1):207-12. doi: 10.1007/s10863-012-9406-7. Review. Erratum in: J Bioenerg Biomembr. 2012 Jun;44(3):397.


Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury.

Zhang WH, Wang H, Wang X, Narayanan MV, Stavrovskaya IG, Kristal BS, Friedlander RM.

Stroke. 2008 Feb;39(2):455-62. doi: 10.1161/STROKEAHA.107.496810. Epub 2008 Jan 3.

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