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Results: 1 to 20 of 100

1.

Selective inhibition of the West Nile virus methyltransferase by nucleoside analogs.

Chen H, Liu L, Jones SA, Banavali N, Kass J, Li Z, Zhang J, Kramer LD, Ghosh AK, Li H.

Antiviral Res. 2013 Mar;97(3):232-9. doi: 10.1016/j.antiviral.2012.12.012. Epub 2012 Dec 22.

PMID:
23267828
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

West Nile virus 5'-cap structure is formed by sequential guanine N-7 and ribose 2'-O methylations by nonstructural protein 5.

Ray D, Shah A, Tilgner M, Guo Y, Zhao Y, Dong H, Deas TS, Zhou Y, Li H, Shi PY.

J Virol. 2006 Sep;80(17):8362-70.

PMID:
16912287
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase.

Dong H, Liu L, Zou G, Zhao Y, Li Z, Lim SP, Shi PY, Li H.

J Biol Chem. 2010 Oct 15;285(42):32586-95. doi: 10.1074/jbc.M110.129197. Epub 2010 Aug 4.

PMID:
20685660
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Structure and function of flavivirus NS5 methyltransferase.

Zhou Y, Ray D, Zhao Y, Dong H, Ren S, Li Z, Guo Y, Bernard KA, Shi PY, Li H.

J Virol. 2007 Apr;81(8):3891-903. Epub 2007 Jan 31.

PMID:
17267492
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism.

Dong H, Ren S, Zhang B, Zhou Y, Puig-Basagoiti F, Li H, Shi PY.

J Virol. 2008 May;82(9):4295-307. doi: 10.1128/JVI.02202-07. Epub 2008 Feb 27.

PMID:
18305027
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Flavivirus methyltransferase: a novel antiviral target.

Dong H, Zhang B, Shi PY.

Antiviral Res. 2008 Oct;80(1):1-10. doi: 10.1016/j.antiviral.2008.05.003. Epub 2008 Jun 5. Review.

PMID:
18571739
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2'-O methylations of viral RNA cap.

Dong H, Ren S, Li H, Shi PY.

Virology. 2008 Jul 20;377(1):1-6. doi: 10.1016/j.virol.2008.04.026. Epub 2008 May 23.

PMID:
18501946
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genetic interactions among the West Nile virus methyltransferase, the RNA-dependent RNA polymerase, and the 5' stem-loop of genomic RNA.

Zhang B, Dong H, Zhou Y, Shi PY.

J Virol. 2008 Jul;82(14):7047-58. doi: 10.1128/JVI.00654-08. Epub 2008 Apr 30.

PMID:
18448528
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Biochemical and genetic characterization of dengue virus methyltransferase.

Dong H, Chang DC, Xie X, Toh YX, Chung KY, Zou G, Lescar J, Lim SP, Shi PY.

Virology. 2010 Sep 30;405(2):568-78. doi: 10.1016/j.virol.2010.06.039. Epub 2010 Jul 23.

PMID:
20655081
[PubMed - indexed for MEDLINE]
Free Article
10.

An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein.

Tan CS, Hobson-Peters JM, Stoermer MJ, Fairlie DP, Khromykh AA, Hall RA.

J Gen Virol. 2013 Sep;94(Pt 9):1961-71. doi: 10.1099/vir.0.054395-0. Epub 2013 Jun 5.

PMID:
23740481
[PubMed - indexed for MEDLINE]
11.

Flavivirus RNA cap methyltransferase: structure, function, and inhibition.

Liu L, Dong H, Chen H, Zhang J, Ling H, Li Z, Shi PY, Li H.

Front Biol (Beijing). 2010 Aug 1;5(4):286-303.

PMID:
21927615
[PubMed]
Free PMC Article
12.

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E.

Antiviral Res. 2013 Sep;99(3):292-300. doi: 10.1016/j.antiviral.2013.06.001. Epub 2013 Jun 12.

PMID:
23769894
[PubMed - indexed for MEDLINE]
13.

2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.

Dong H, Chang DC, Hua MH, Lim SP, Chionh YH, Hia F, Lee YH, Kukkaro P, Lok SM, Dedon PC, Shi PY.

PLoS Pathog. 2012;8(4):e1002642. doi: 10.1371/journal.ppat.1002642. Epub 2012 Apr 5.

PMID:
22496660
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase.

Chen H, Zhou B, Brecher M, Banavali N, Jones SA, Li Z, Zhang J, Nag D, Kramer LD, Ghosh AK, Li H.

PLoS One. 2013 Oct 9;8(10):e76900. doi: 10.1371/journal.pone.0076900. eCollection 2013.

PMID:
24130807
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease.

Ezgimen M, Lai H, Mueller NH, Lee K, Cuny G, Ostrov DA, Padmanabhan R.

Antiviral Res. 2012 Apr;94(1):18-24. doi: 10.1016/j.antiviral.2012.02.003. Epub 2012 Feb 11.

PMID:
22343093
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo.

Szretter KJ, Daniels BP, Cho H, Gainey MD, Yokoyama WM, Gale M Jr, Virgin HW, Klein RS, Sen GC, Diamond MS.

PLoS Pathog. 2012;8(5):e1002698. doi: 10.1371/journal.ppat.1002698. Epub 2012 May 10.

PMID:
22589727
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification and characterization of inhibitors of West Nile virus.

Puig-Basagoiti F, Qing M, Dong H, Zhang B, Zou G, Yuan Z, Shi PY.

Antiviral Res. 2009 Jul;83(1):71-9. doi: 10.1016/j.antiviral.2009.03.005. Epub 2009 Apr 1.

PMID:
19501258
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase.

Mastrangelo E, Bollati M, Milani M, Selisko B, Peyrane F, Canard B, Grard G, de Lamballerie X, Bolognesi M.

Protein Sci. 2007 Jun;16(6):1133-45. Epub 2007 May 1.

PMID:
17473012
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells.

Jordan I, Briese T, Fischer N, Lau JY, Lipkin WI.

J Infect Dis. 2000 Oct;182(4):1214-7. Epub 2000 Aug 22.

PMID:
10979920
[PubMed - indexed for MEDLINE]
Free Article
20.

Genetic systems of West Nile virus and their potential applications.

Shi PY.

Curr Opin Investig Drugs. 2003 Aug;4(8):959-65. Review.

PMID:
14508880
[PubMed - indexed for MEDLINE]

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