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Results: 1 to 20 of 111

1.

PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathways.

Clement DL, Mally S, Stock C, Lethan M, Satir P, Schwab A, Pedersen SF, Christensen ST.

J Cell Sci. 2013 Feb 15;126(Pt 4):953-65. doi: 10.1242/jcs.116426. Epub 2012 Dec 21.

PMID:
23264740
[PubMed - indexed for MEDLINE]
Free Article
2.

PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts.

Schneider L, Clement CA, Teilmann SC, Pazour GJ, Hoffmann EK, Satir P, Christensen ST.

Curr Biol. 2005 Oct 25;15(20):1861-6.

PMID:
16243034
[PubMed - indexed for MEDLINE]
Free Article
3.

The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium.

Schneider L, Stock CM, Dieterich P, Jensen BH, Pedersen LB, Satir P, Schwab A, Christensen ST, Pedersen SF.

J Cell Biol. 2009 Apr 6;185(1):163-76. doi: 10.1083/jcb.200806019.

PMID:
19349585
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors.

Meima ME, Webb BA, Witkowska HE, Barber DL.

J Biol Chem. 2009 Sep 25;284(39):26666-75. doi: 10.1074/jbc.M109.019448. Epub 2009 Jul 21.

PMID:
19622752
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Analysis of primary cilia in directional cell migration in fibroblasts.

Christensen ST, Veland IR, Schwab A, Cammer M, Satir P.

Methods Enzymol. 2013;525:45-58. doi: 10.1016/B978-0-12-397944-5.00003-1.

PMID:
23522464
[PubMed - indexed for MEDLINE]
6.

Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes.

Chen S, Mackintosh C.

Cell Signal. 2009 Dec;21(12):1984-93. doi: 10.1016/j.cellsig.2009.09.009. Epub 2009 Sep 15.

PMID:
19765648
[PubMed - indexed for MEDLINE]
Free Article
7.

ERK1/2-p90RSK-mediated phosphorylation of Na+/H+ exchanger isoform 1. A role in ischemic neuronal death.

Luo J, Kintner DB, Shull GE, Sun D.

J Biol Chem. 2007 Sep 21;282(38):28274-84. Epub 2007 Jul 30.

PMID:
17664275
[PubMed - indexed for MEDLINE]
Free Article
8.

The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.

Lauritzen G, Stock CM, Lemaire J, Lund SF, Jensen MF, Damsgaard B, Petersen KS, Wiwel M, Rønnov-Jessen L, Schwab A, Pedersen SF.

Cancer Lett. 2012 Apr 28;317(2):172-83. doi: 10.1016/j.canlet.2011.11.023. Epub 2011 Nov 25.

PMID:
22120673
[PubMed - indexed for MEDLINE]
9.

Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts.

Schneider L, Cammer M, Lehman J, Nielsen SK, Guerra CF, Veland IR, Stock C, Hoffmann EK, Yoder BK, Schwab A, Satir P, Christensen ST.

Cell Physiol Biochem. 2010;25(2-3):279-92. doi: 10.1159/000276562. Epub 2010 Jan 12.

PMID:
20110689
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

EGF upregulates Na+/H+ exchanger NHE1 by post-translational regulation that is important for cervical cancer cell invasiveness.

Chiang Y, Chou CY, Hsu KF, Huang YF, Shen MR.

J Cell Physiol. 2008 Mar;214(3):810-9.

PMID:
17894388
[PubMed - indexed for MEDLINE]
11.

Acidosis-mediated regulation of the NHE1 isoform of the Na⁺/H⁺ exchanger in renal cells.

Odunewu A, Fliegel L.

Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F370-81. doi: 10.1152/ajprenal.00598.2012. Epub 2013 May 15.

PMID:
23678047
[PubMed - indexed for MEDLINE]
Free Article
12.

The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells.

Pedersen SF, Darborg BV, Rasmussen M, Nylandsted J, Hoffmann EK.

Cell Physiol Biochem. 2007;20(6):735-50.

PMID:
17982256
[PubMed - indexed for MEDLINE]
13.

Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2.

Kintner DB, Look A, Shull GE, Sun D.

Am J Physiol Cell Physiol. 2005 Oct;289(4):C934-45. Epub 2005 May 18.

PMID:
15901600
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.

Veland IR, Montjean R, Eley L, Pedersen LB, Schwab A, Goodship J, Kristiansen K, Pedersen SF, Saunier S, Christensen ST.

PLoS One. 2013 Apr 8;8(4):e60193. doi: 10.1371/journal.pone.0060193. Print 2013.

PMID:
23593172
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Sustained intracellular acidosis activates the myocardial Na(+)/H(+) exchanger independent of amino acid Ser(703) and p90(rsk).

Karki P, Coccaro E, Fliegel L.

Biochim Biophys Acta. 2010 Aug;1798(8):1565-76. doi: 10.1016/j.bbamem.2010.05.005. Epub 2010 May 13.

PMID:
20471361
[PubMed - indexed for MEDLINE]
Free Article
16.

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

Denker SP, Barber DL.

J Cell Biol. 2002 Dec 23;159(6):1087-96. Epub 2002 Dec 16.

PMID:
12486114
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Protein kinase B/Akt phosphorylates and inhibits the cardiac Na+/H+ exchanger NHE1.

Snabaitis AK, Cuello F, Avkiran M.

Circ Res. 2008 Oct 10;103(8):881-90. doi: 10.1161/CIRCRESAHA.108.175877. Epub 2008 Aug 28.

PMID:
18757828
[PubMed - indexed for MEDLINE]
Free Article
18.

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells.

Paradiso A, Cardone RA, Bellizzi A, Bagorda A, Guerra L, Tommasino M, Casavola V, Reshkin SJ.

Breast Cancer Res. 2004;6(6):R616-28. Epub 2004 Sep 13.

PMID:
15535843
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury.

Maekawa N, Abe J, Shishido T, Itoh S, Ding B, Sharma VK, Sheu SS, Blaxall BC, Berk BC.

Circulation. 2006 May 30;113(21):2516-23. Epub 2006 May 22.

PMID:
16717153
[PubMed - indexed for MEDLINE]
Free Article
20.

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

Rasmussen M, Alexander RT, Darborg BV, Møbjerg N, Hoffmann EK, Kapus A, Pedersen SF.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C197-212. Epub 2007 Oct 31.

PMID:
17977945
[PubMed - indexed for MEDLINE]
Free Article

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