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Items: 1 to 20 of 107

1.

Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants.

Young TS, Dorrestein PC, Walsh CT.

Chem Biol. 2012 Dec 21;19(12):1600-10. doi: 10.1016/j.chembiol.2012.10.013.

2.

Total synthesis and stereochemical assignment of baringolin.

Just-Baringo X, Bruno P, Ottesen LK, Cañedo LM, Albericio F, Álvarez M.

Angew Chem Int Ed Engl. 2013 Jul 22;52(30):7818-21. doi: 10.1002/anie.201302372. Epub 2013 Jun 18.

PMID:
23780649
3.

Nocardithiocin, a novel thiopeptide antibiotic, produced by pathogenic Nocardia pseudobrasiliensis IFM 0757.

Mukai A, Fukai T, Hoshino Y, Yazawa K, Harada K, Mikami Y.

J Antibiot (Tokyo). 2009 Nov;62(11):613-9. doi: 10.1038/ja.2009.90. Epub 2009 Sep 11. Erratum in: J Antibiot (Tokyo). 2010 Feb;63(2):99.

PMID:
19745839
4.

Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans.

Young TS, Walsh CT.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13053-8. doi: 10.1073/pnas.1110435108. Epub 2011 Jul 25.

5.

In vitro and in vivo activities of novel, semisynthetic thiopeptide inhibitors of bacterial elongation factor Tu.

Leeds JA, LaMarche MJ, Brewer JT, Bushell SM, Deng G, Dewhurst JM, Dzink-Fox J, Gangl E, Jain A, Lee L, Lilly M, Manni K, Mullin S, Neckermann G, Osborne C, Palestrant D, Patane MA, Raimondi A, Ranjitkar S, Rann EM, Sachdeva M, Shao J, Tiamfook S, Whitehead L, Yu D.

Antimicrob Agents Chemother. 2011 Nov;55(11):5277-83. doi: 10.1128/AAC.00582-11. Epub 2011 Aug 8.

6.

Antibiotic GE37468 A: a new inhibitor of bacterial protein synthesis. I. Isolation and characterization.

Stella S, Montanini N, Le Monnier F, Ferrari P, Colombo L, Marinelli F, Landini P, Ciciliato I, Goldstein BP, Selva E, et al.

J Antibiot (Tokyo). 1995 Aug;48(8):780-6. Erratum in: J Antibiot (Tokyo) 1995 Dec;48(12):C-3.

7.

In vivo production of thiopeptide variants.

Zhang F, Kelly WL.

Methods Enzymol. 2012;516:3-24. doi: 10.1016/B978-0-12-394291-3.00022-8.

PMID:
23034221
8.

Kocurin, the true structure of PM181104, an anti-methicillin-resistant Staphylococcus aureus (MRSA) thiazolyl peptide from the marine-derived bacterium Kocuria palustris.

Martín J, da S Sousa T, Crespo G, Palomo S, González I, Tormo JR, de la Cruz M, Anderson M, Hill RT, Vicente F, Genilloud O, Reyes F.

Mar Drugs. 2013 Feb 4;11(2):387-98. doi: 10.3390/md11020387.

9.

The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds.

Malcolmson SJ, Young TS, Ruby JG, Skewes-Cox P, Walsh CT.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8483-8. doi: 10.1073/pnas.1307111110. Epub 2013 May 6.

10.

Isolation and characterization of two novel antibacterial cyclic hexapeptides from Streptomyces alboflavus 313.

Ji Z, Qiao G, Wei S, Fan L, Wu W.

Chem Biodivers. 2012 Aug;9(8):1567-78. doi: 10.1002/cbdv.201100364.

PMID:
22899617
11.
12.

Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.

Tocchetti A, Maffioli S, Iorio M, Alt S, Mazzei E, Brunati C, Sosio M, Donadio S.

Chem Biol. 2013 Aug 22;20(8):1067-77. doi: 10.1016/j.chembiol.2013.07.005. Epub 2013 Aug 8.

13.
14.

Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.

Morris RP, Leeds JA, Naegeli HU, Oberer L, Memmert K, Weber E, LaMarche MJ, Parker CN, Burrer N, Esterow S, Hein AE, Schmitt EK, Krastel P.

J Am Chem Soc. 2009 Apr 29;131(16):5946-55. doi: 10.1021/ja900488a.

PMID:
19338336
15.

Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22.

Wang J, Yu Y, Tang K, Liu W, He X, Huang X, Deng Z.

Appl Environ Microbiol. 2010 Apr;76(7):2335-44. doi: 10.1128/AEM.01790-09. Epub 2010 Feb 12.

16.

Radamycin, a novel thiopeptide produced by streptomyces sp. RSP9. II. Physico-chemical properties and structure determination.

Castro Rodríguez J, González Holgado G, Santamaría Sánchez RI, Cañedo LM.

J Antibiot (Tokyo). 2002 Apr;55(4):391-5.

17.

Identification and characterisation of a Streptomyces sp. isolate exhibiting activity against methicillin-resistant Staphylococcus aureus.

Higginbotham SJ, Murphy CD.

Microbiol Res. 2010;165(1):82-6. doi: 10.1016/j.micres.2008.12.004. Epub 2009 Feb 20.

18.

Antibiotic GE37468 A: a novel inhibitor of bacterial protein synthesis. II. Structure elucidation.

Ferrari P, Colombo L, Stella S, Selva E, Zerilli LF.

J Antibiot (Tokyo). 1995 Nov;48(11):1304-11.

19.

Enduracidin analogues with altered halogenation patterns produced by genetically engineered strains of Streptomyces fungicidicus.

Yin X, Chen Y, Zhang L, Wang Y, Zabriskie TM.

J Nat Prod. 2010 Apr 23;73(4):583-9. doi: 10.1021/np900710q.

20.

Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.

Yu Y, Duan L, Zhang Q, Liao R, Ding Y, Pan H, Wendt-Pienkowski E, Tang G, Shen B, Liu W.

ACS Chem Biol. 2009 Oct 16;4(10):855-64. doi: 10.1021/cb900133x.

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