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Items: 1 to 20 of 205

1.

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells.

Carbajo-Pescador S, Steinmetz C, Kashyap A, Lorenz S, Mauriz JL, Heise M, Galle PR, González-Gallego J, Strand S.

Br J Cancer. 2013 Feb 5;108(2):442-9. doi: 10.1038/bjc.2012.563. Epub 2012 Dec 20.

2.

Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis.

Barreyro FJ, Kobayashi S, Bronk SF, Werneburg NW, Malhi H, Gores GJ.

J Biol Chem. 2007 Sep 14;282(37):27141-54. Epub 2007 Jul 11.

3.

Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma.

Wang JG, Zheng XX, Zeng GY, Zhou YJ, Yuan H.

Oncol Rep. 2014 Jan;31(1):488-96. doi: 10.3892/or.2013.2855. Epub 2013 Nov 15.

PMID:
24247909
4.

Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells.

Wildey GM, Howe PH.

J Biol Chem. 2009 Jul 24;284(30):20227-39. doi: 10.1074/jbc.M109.027201. Epub 2009 Jun 3.

5.

FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.

Shukla S, Rizvi F, Raisuddin S, Kakkar P.

Free Radic Biol Med. 2014 Nov;76:185-99. doi: 10.1016/j.freeradbiomed.2014.07.039. Epub 2014 Aug 13.

PMID:
25128467
6.

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines.

Sunters A, Fernández de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA, Coffer PJ, Medema RH, Coombes RC, Lam EW.

J Biol Chem. 2003 Dec 12;278(50):49795-805. Epub 2003 Oct 3.

7.

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW.

Oncogene. 2005 Mar 31;24(14):2317-29.

PMID:
15688014
8.

18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.

Sharma G, Kar S, Palit S, Das PK.

J Cell Physiol. 2012 May;227(5):1923-31. doi: 10.1002/jcp.22920.

PMID:
21732363
9.

RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells.

Yamamura Y, Lee WL, Inoue K, Ida H, Ito Y.

J Biol Chem. 2006 Feb 24;281(8):5267-76. Epub 2005 Dec 22.

10.

NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons.

Hughes R, Kristiansen M, Lassot I, Desagher S, Mantovani R, Ham J.

Cell Death Differ. 2011 Jun;18(6):937-47. doi: 10.1038/cdd.2010.166. Epub 2010 Dec 17.

11.

HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of FoxO3a and altering its localization.

Tanaka-Nakanishi A, Yasunaga J, Takai K, Matsuoka M.

Cancer Res. 2014 Jan 1;74(1):188-200. doi: 10.1158/0008-5472.CAN-13-0436. Epub 2013 Oct 31.

12.

Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.

Guan H, Song L, Cai J, Huang Y, Wu J, Yuan J, Li J, Li M.

PLoS One. 2011;6(5):e19946. doi: 10.1371/journal.pone.0019946. Epub 2011 May 18.

13.

Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells.

Park EJ, Woo SM, Min KJ, Kwon TK.

J Pineal Res. 2014 Jan;56(1):97-106. doi: 10.1111/jpi.12102. Epub 2013 Nov 8.

PMID:
24117987
14.

Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

Möller C, Alfredsson J, Engström M, Wootz H, Xiang Z, Lennartsson J, Jönsson JI, Nilsson G.

Blood. 2005 Aug 15;106(4):1330-6. Epub 2005 Apr 26.

15.

FOXO3-mediated up-regulation of Bim contributes to rhein-induced cancer cell apoptosis.

Wang J, Liu S, Yin Y, Li M, Wang B, Yang L, Jiang Y.

Apoptosis. 2015 Mar;20(3):399-409. doi: 10.1007/s10495-014-1071-3.

PMID:
25501496
16.

Follicle-stimulating hormone regulates pro-apoptotic protein Bcl-2-interacting mediator of cell death-extra long (BimEL)-induced porcine granulosa cell apoptosis.

Wang XL, Wu Y, Tan LB, Tian Z, Liu JH, Zhu DS, Zeng SM.

J Biol Chem. 2012 Mar 23;287(13):10166-77. doi: 10.1074/jbc.M111.293274. Epub 2012 Jan 10.

17.

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms.

De Bruyne E, Bos TJ, Schuit F, Van Valckenborgh E, Menu E, Thorrez L, Atadja P, Jernberg-Wiklund H, Vanderkerken K.

Blood. 2010 Mar 25;115(12):2430-40. doi: 10.1182/blood-2009-07-232801. Epub 2010 Jan 19.

18.

BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

Yuan Z, Wang F, Zhao Z, Zhao X, Qiu J, Nie C, Wei Y.

PLoS One. 2011;6(5):e20586. doi: 10.1371/journal.pone.0020586. Epub 2011 May 31.

19.

Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.

Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA.

PLoS One. 2010 Sep 27;5(9):e13026. doi: 10.1371/journal.pone.0013026.

20.

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.

Stan SD, Hahm ER, Warin R, Singh SV.

Cancer Res. 2008 Sep 15;68(18):7661-9. doi: 10.1158/0008-5472.CAN-08-1510.

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