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Results: 1 to 20 of 101

1.

Mechanism-based inhibition of CYP1A1 and CYP3A4 by the furanocoumarin chalepensin.

Ueng YF, Chen CC, Yamazaki H, Kiyotani K, Chang YP, Lo WS, Li DT, Tsai PL.

Drug Metab Pharmacokinet. 2013;28(3):229-38. Epub 2012 Dec 18.

PMID:
23257392
[PubMed - indexed for MEDLINE]
Free Article
2.

Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.

Ueng YF, Chen CC, Chung YT, Liu TY, Chang YP, Lo WS, Murayama N, Yamazaki H, Souček P, Chau GY, Chi CW, Chen RM, Li DT.

Br J Pharmacol. 2011 Jul;163(6):1250-62. doi: 10.1111/j.1476-5381.2011.01341.x.

PMID:
21418183
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A dual function of the furanocoumarin chalepensin in inhibiting Cyp2a and inducing Cyp2b in mice: the protein stabilization and receptor-mediated activation.

Lo WS, Lim YP, Chen CC, Hsu CC, Souček P, Yun CH, Xie W, Ueng YF.

Arch Toxicol. 2012 Dec;86(12):1927-38. doi: 10.1007/s00204-012-0902-7. Epub 2012 Jul 12.

PMID:
22790670
[PubMed - indexed for MEDLINE]
4.

Inhibition selectivity of grapefruit juice components on human cytochromes P450.

Tassaneeyakul W, Guo LQ, Fukuda K, Ohta T, Yamazoe Y.

Arch Biochem Biophys. 2000 Jun 15;378(2):356-63.

PMID:
10860553
[PubMed - indexed for MEDLINE]
5.

Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.

Wen X, Wang JS, Neuvonen PJ, Backman JT.

Eur J Clin Pharmacol. 2002 Jan;57(11):799-804.

PMID:
11868802
[PubMed - indexed for MEDLINE]
6.

Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.

Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2000 Oct;30(10):955-69.

PMID:
11315104
[PubMed - indexed for MEDLINE]
7.

Development of novel furanocoumarin dimers as potent and selective inhibitors of CYP3A4.

Row E, Brown SA, Stachulski AV, Lennard MS.

Drug Metab Dispos. 2006 Feb;34(2):324-30. Epub 2005 Nov 18.

PMID:
16299162
[PubMed - indexed for MEDLINE]
Free Article
8.

Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.

Kranendonk M, Carreira F, Theisen P, Laires A, Fisher CW, Rueff J, Estabrook RW, Vermeulen NP.

Mutat Res. 1999 Apr 26;441(1):73-83.

PMID:
10224324
[PubMed - indexed for MEDLINE]
9.

Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.

Butler AM, Murray M.

J Pharmacol Exp Ther. 1997 Feb;280(2):966-73.

PMID:
9023313
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2.

Chang TK, Chen J, Lee WB.

J Pharmacol Exp Ther. 2001 Dec;299(3):874-82.

PMID:
11714871
[PubMed - indexed for MEDLINE]
Free Article
12.

Inhibition of CYP3A4 and CYP2C9 by podophyllotoxin: implication for clinical drug-drug interactions.

Song JH, Sun DX, Chen B, Ji DH, Pu J, Xu J, Tian FD, Guo L.

J Biosci. 2011 Dec;36(5):879-85.

PMID:
22116286
[PubMed - indexed for MEDLINE]
Free Article
13.

Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate.

Lillibridge JH, Liang BH, Kerr BM, Webber S, Quart B, Shetty BV, Lee CA.

Drug Metab Dispos. 1998 Jul;26(7):609-16.

PMID:
9660842
[PubMed - indexed for MEDLINE]
Free Article
14.

Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes.

Qi XY, Liang SC, Ge GB, Liu Y, Dong PP, Zhang JW, Wang AX, Hou J, Zhu LL, Yang L, Tu CX.

Food Chem Toxicol. 2013 Jun;56:392-7. doi: 10.1016/j.fct.2013.02.054. Epub 2013 Mar 14.

PMID:
23500771
[PubMed - indexed for MEDLINE]
15.

Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds.

Nakajima M, Suzuki M, Yamaji R, Takashina H, Shimada N, Yamazaki H, Yokoi T.

Xenobiotica. 1999 Dec;29(12):1191-202.

PMID:
10647906
[PubMed - indexed for MEDLINE]
16.

Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole.

Ueng YF, Hsieh CH, Don MJ.

Food Chem Toxicol. 2005 May;43(5):707-12.

PMID:
15778010
[PubMed - indexed for MEDLINE]
17.

Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.

Hanioka N, Ozawa S, Jinno H, Tanaka-Kagawa T, Nishimura T, Ando M, Sawada Ji J.

Drug Metab Dispos. 2002 Apr;30(4):391-6.

PMID:
11901092
[PubMed - indexed for MEDLINE]
Free Article
18.

Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes.

Cohen LH, van Leeuwen RE, van Thiel GC, van Pelt JF, Yap SH.

Biopharm Drug Dispos. 2000 Dec;21(9):353-64.

PMID:
11523064
[PubMed - indexed for MEDLINE]
19.

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.

Fang ZZ, Zhang YY, Ge GB, Huo H, Liang SC, Yang L.

Br J Clin Pharmacol. 2010 Feb;69(2):193-9. doi: 10.1111/j.1365-2125.2009.03572.x.

PMID:
20233183
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.

Koenigs LL, Peter RM, Thompson SJ, Rettie AE, Trager WF.

Drug Metab Dispos. 1997 Dec;25(12):1407-15.

PMID:
9394031
[PubMed - indexed for MEDLINE]
Free Article

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