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Items: 1 to 20 of 212

1.

Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.

Fan H, Zhao X, Sun S, Luo M, Guan JL.

J Biol Chem. 2013 Feb 1;288(5):3322-33. doi: 10.1074/jbc.M112.420497. Epub 2012 Dec 19.

2.

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells.

Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL.

Cancer Res. 2009 Jan 15;69(2):466-74. doi: 10.1158/0008-5472.CAN-08-3078.

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Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.

Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ.

Am J Pathol. 2008 Nov;173(5):1551-65. doi: 10.2353/ajpath.2008.080308. Epub 2008 Oct 9.

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Distinct FAK activities determine progenitor and mammary stem cell characteristics.

Luo M, Zhao X, Chen S, Liu S, Wicha MS, Guan JL.

Cancer Res. 2013 Sep 1;73(17):5591-602. doi: 10.1158/0008-5472.CAN-13-1351. Epub 2013 Jul 5.

7.

Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer.

Guan JL.

IUBMB Life. 2010 Apr;62(4):268-76. doi: 10.1002/iub.303. Review.

8.

CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer.

Chen YS, Wu MJ, Huang CY, Lin SC, Chuang TH, Yu CC, Lo JF.

PLoS One. 2011;6(11):e28053. doi: 10.1371/journal.pone.0028053. Epub 2011 Nov 28.

9.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

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TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer.

Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP.

Oncogene. 2013 Apr 18;32(16):2005-15. doi: 10.1038/onc.2012.230. Epub 2012 Jun 18.

12.

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression.

Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, Muller WJ.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20302-7. Epub 2007 Dec 3.

13.

Differential effect of the focal adhesion kinase Y397F mutant on v-Src-stimulated cell invasion and tumor growth.

Chang LC, Huang CH, Cheng CH, Chen BH, Chen HC.

J Biomed Sci. 2005;12(4):571-85. Epub 2005 Nov 10.

PMID:
16132110
14.

Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.

Zheng Y, Gierut J, Wang Z, Miao J, Asara JM, Tyner AL.

Oncogene. 2013 Sep 5;32(36):4304-12. doi: 10.1038/onc.2012.427. Epub 2012 Oct 1.

15.

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.

Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, Smith KD, Cushing RC, Seagroves TN.

Breast Cancer Res. 2012 Jan 7;14(1):R6.

16.

Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation.

van Nimwegen MJ, Verkoeijen S, van Buren L, Burg D, van de Water B.

Cancer Res. 2005 Jun 1;65(11):4698-706.

17.

Membrane Type 1 Matrix Metalloproteinase induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells.

Yang CC, Zhu LF, Xu XH, Ning TY, Ye JH, Liu LK.

BMC Cancer. 2013 Apr 1;13:171. doi: 10.1186/1471-2407-13-171.

18.

Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells.

Nagaharu K, Zhang X, Yoshida T, Katoh D, Hanamura N, Kozuka Y, Ogawa T, Shiraishi T, Imanaka-Yoshida K.

Am J Pathol. 2011 Feb;178(2):754-63. doi: 10.1016/j.ajpath.2010.10.015.

19.

Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models.

Dunlap SM, Chiao LJ, Nogueira L, Usary J, Perou CM, Varticovski L, Hursting SD.

Cancer Prev Res (Phila). 2012 Jul;5(7):930-42. doi: 10.1158/1940-6207.CAPR-12-0034. Epub 2012 May 15.

20.

MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.

Kong X, Li G, Yuan Y, He Y, Wu X, Zhang W, Wu Z, Chen T, Wu W, Lobie PE, Zhu T.

PLoS One. 2012;7(8):e41523. doi: 10.1371/journal.pone.0041523. Epub 2012 Aug 2.

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