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Items: 1 to 20 of 102

1.

Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics.

Schmeits PC, Volger OL, Zandvliet ET, van Loveren H, Peijnenburg AA, Hendriksen PJ.

Toxicol Lett. 2013 Feb 13;217(1):1-13. doi: 10.1016/j.toxlet.2012.12.005. Epub 2012 Dec 17.

PMID:
23253260
2.

DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells.

Schmeits PC, Katika MR, Peijnenburg AA, van Loveren H, Hendriksen PJ.

Toxicol Lett. 2014 Jan 30;224(3):395-406. doi: 10.1016/j.toxlet.2013.11.005. Epub 2013 Nov 15.

PMID:
24247028
3.

Exposure of Jurkat cells to bis (tri-n-butyltin) oxide (TBTO) induces transcriptomics changes indicative for ER- and oxidative stress, T cell activation and apoptosis.

Katika MR, Hendriksen PJ, van Loveren H, Peijnenburg A.

Toxicol Appl Pharmacol. 2011 Aug 1;254(3):311-22. doi: 10.1016/j.taap.2011.04.021. Epub 2011 May 13.

PMID:
21601586
4.

Transcriptome analysis of the human T lymphocyte cell line Jurkat and human peripheral blood mononuclear cells exposed to deoxynivalenol (DON): New mechanistic insights.

Katika MR, Hendriksen PJ, Shao J, van Loveren H, Peijnenburg A.

Toxicol Appl Pharmacol. 2012 Oct 1;264(1):51-64. doi: 10.1016/j.taap.2012.07.017. Epub 2012 Jul 28.

PMID:
22846391
5.

Immunocytological and biochemical analysis of the mode of action of bis (tri-n-butyltin) tri-oxide (TBTO) in Jurkat cells.

Katika MR, Hendriksen PJ, de Ruijter NC, van Loveren H, Peijnenburg A.

Toxicol Lett. 2012 Jul 20;212(2):126-36. doi: 10.1016/j.toxlet.2012.05.010. Epub 2012 May 18.

PMID:
22613032
6.

Transcriptomics analysis of primary mouse thymocytes exposed to bis(tri-n-butyltin)dioxide (TBTO).

van Kol SW, Hendriksen PJ, van Loveren H, Peijnenburg A.

Toxicology. 2012 Jun 14;296(1-3):37-47. doi: 10.1016/j.tox.2012.03.002. Epub 2012 Mar 14.

PMID:
22434021
7.

In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics.

Baken KA, Arkusz J, Pennings JL, Vandebriel RJ, van Loveren H.

Toxicology. 2007 Jul 31;237(1-3):35-48. Epub 2007 May 5.

PMID:
17553608
8.

Characterization of the modes of action of deoxynivalenol (DON) in the human Jurkat T-cell line.

Katika MR, Hendriksen PJ, van Loveren H, A C M Peijnenburg A.

J Immunotoxicol. 2015 Jul-Sep;12(3):206-16. doi: 10.3109/1547691X.2014.925995. Epub 2014 Jul 2.

PMID:
24988111
9.
10.

Induction of apoptosis and activation of JNK and p38 MAPK pathways in deoxynivalenol-treated cell lines.

Baltriukiene D, Kalvelyte A, Bukelskiene V.

Altern Lab Anim. 2007 Mar;35(1):53-9.

11.

Dual roles of sphingolipids in signaling of the escape from and onset of apoptosis in a mouse cytotoxic T-cell line, CTLL-2.

Nakamura S, Kozutsumi Y, Sun Y, Miyake Y, Fujita T, Kawasaki T.

J Biol Chem. 1996 Jan 19;271(3):1255-7.

13.

JAK/STAT pathway plays a critical role in the proinflammatory gene expression and apoptosis of RAW264.7 cells induced by trichothecenes as DON and T-2 toxin.

Wang X, Liu Q, Ihsan A, Huang L, Dai M, Hao H, Cheng G, Liu Z, Wang Y, Yuan Z.

Toxicol Sci. 2012 Jun;127(2):412-24. doi: 10.1093/toxsci/kfs106. Epub 2012 Mar 27.

14.

Proteomic analysis of mouse thymoma EL4 cells treated with bis(tri-n-butyltin)oxide (TBTO).

Osman AM, van Kol S, Peijnenburg A, Blokland M, Pennings JL, Kleinjans JC, van Loveren H.

J Immunotoxicol. 2009 Sep;6(3):174-83. doi: 10.3109/15476910903496691.

PMID:
19552622
15.

Transcriptome-based functional classifiers for direct immunotoxicity.

Shao J, Berger LF, Hendriksen PJ, Peijnenburg AA, van Loveren H, Volger OL.

Arch Toxicol. 2014 Mar;88(3):673-89. doi: 10.1007/s00204-013-1179-1. Epub 2013 Dec 20.

PMID:
24356939
16.

Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models.

Schmeits PC, Schaap MM, Luijten M, van Someren E, Boorsma A, van Loveren H, Peijnenburg AA, Hendriksen PJ.

Arch Toxicol. 2015 Dec;89(12):2325-37. doi: 10.1007/s00204-014-1365-9. Epub 2014 Sep 17.

PMID:
25224403
17.

The effects of deoxynivalenol on gene expression in the murine thymus.

van Kol SW, Hendriksen PJ, van Loveren H, Peijnenburg A.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):299-311. doi: 10.1016/j.taap.2010.11.001. Epub 2010 Nov 11.

18.

Toxicity of bis(tri-n-butyltin)oxide in the rat. II. Suppression of thymus-dependent immune responses and of parameters of nonspecific resistance after short-term exposure.

Vos JG, de Klerk A, Krajnc EI, Kruizinga W, van Ommen B, Rozing J.

Toxicol Appl Pharmacol. 1984 Sep 30;75(3):387-408.

PMID:
6474470
19.
20.

Lysophosphatidylcholine induces Ca(2+) mobilization in Jurkat human T lymphocytes and CTLL-2 mouse T lymphocytes by different pathways.

Wang Q, Wu YJ.

Eur J Pharm Sci. 2011 Dec 18;44(5):602-9. doi: 10.1016/j.ejps.2011.10.007. Epub 2011 Oct 14.

PMID:
22019492
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