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Items: 1 to 20 of 120

1.

Sivelestat improves outcome of crush injury by inhibiting high-mobility group box 1 in rats.

Cuong NT, Abe C, Binh NH, Hara A, Morita H, Ogura S.

Shock. 2013 Jan;39(1):89-95. doi: 10.1097/SHK.0b013e31827a2412.

PMID:
23247125
2.

A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.

Hagiwara S, Iwasaka H, Togo K, Noguchi T.

Inflammation. 2008 Aug;31(4):227-34. doi: 10.1007/s10753-008-9069-z.

PMID:
18536984
3.

The effect of the neutrophil elastase inhibitor sivelestat on early injury after liver resection.

Tsujii S, Okabayashi T, Shiga M, Takezaki Y, Sugimoto T, Kobayashi M, Hanazaki K.

World J Surg. 2012 May;36(5):1122-7. doi: 10.1007/s00268-012-1501-8.

PMID:
22366983
4.

Neutrophil elastase inhibitor improves survival of rats with clinically relevant sepsis.

Suda K, Takeuchi H, Hagiwara T, Miyasho T, Okamoto M, Kawasako K, Yamada S, Suganuma K, Wada N, Saikawa Y, Fukunaga K, Funakoshi Y, Hashimoto S, Yokota H, Maruyama I, Ishizaka A, Kitagawa Y.

Shock. 2010 May;33(5):526-31. doi: 10.1097/SHK.0b013e3181cc064b.

PMID:
19953005
5.

Neutrophil elastase inhibitor improves survival rate after ischemia reperfusion injury caused by supravisceral aortic clamping in rats.

Fujimura N, Obara H, Suda K, Takeuchi H, Miyasho T, Kawasako K, Du W, Yamada S, Ono S, Matsumoto K, Matsuda S, Yagi H, Kitago M, Shinoda M, Itano O, Tanabe M, Sakamoto M, Maruyama I, Kitagawa Y.

J Surg Res. 2013 Mar;180(1):e31-6. doi: 10.1016/j.jss.2012.04.037. Epub 2012 May 8.

PMID:
22595015
6.

Systemic involvement of high-mobility group box 1 protein and therapeutic effect of anti-high-mobility group box 1 protein antibody in a rat model of crush injury.

Shimazaki J, Matsumoto N, Ogura H, Muroya T, Kuwagata Y, Nakagawa J, Yamakawa K, Hosotsubo H, Imamura Y, Shimazu T.

Shock. 2012 Jun;37(6):634-8. doi: 10.1097/SHK.0b013e31824ed6b7.

PMID:
22392147
7.

Prevention of leukocyte activation by the neutrophil elastase inhibitor, sivelestat, in the hepatic microcirculation after ischemia-reperfusion.

Nakano Y, Kondo T, Matsuo R, Murata S, Fukunaga K, Ohkohchi N.

J Surg Res. 2009 Aug;155(2):311-7. doi: 10.1016/j.jss.2008.07.025. Epub 2008 Aug 27.

PMID:
19482311
8.
9.

Prospective randomized controlled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer.

Kawahara Y, Ninomiya I, Fujimura T, Funaki H, Nakagawara H, Takamura H, Oyama K, Tajima H, Fushida S, Inaba H, Kayahara M.

Dis Esophagus. 2010 May;23(4):329-39. doi: 10.1111/j.1442-2050.2009.01010.x. Epub 2009 Sep 25.

PMID:
19788440
10.

Protective effect of Sivelestat in a porcine hepatectomy model prepared using an intermittent Pringle method.

Shimoda M, Iwasaki Y, Okada T, Sawada T, Kubota K.

Eur J Pharmacol. 2008 Jun 10;587(1-3):248-52. doi: 10.1016/j.ejphar.2008.02.064. Epub 2008 Feb 29.

PMID:
18374331
11.

Synergistic effects of recombinant human soluble thrombomodulin and fluid-volume resuscitation in a rat lethal crush injury model.

Mohri T, Tanaka H, Tajima G, Kajino K, Sonoi H, Hosotsubo H, Ogura H, Kuwagata Y, Shimazu T, Sugimoto H.

Shock. 2006 Dec;26(6):581-6.

PMID:
17117133
12.

Addition of a neutrophil elastase inhibitor to the organ flushing solution decreases lung reperfusion injury in rat lung transplantation.

Mori H, Nagahiro I, Osaragi T, Kotani K, Nakanishi H, Sano Y, Date H, Shimizu N.

Eur J Cardiothorac Surg. 2007 Nov;32(5):791-5. Epub 2007 Sep 20.

PMID:
17888675
13.

Potential of sivelestat in protection against severe acute pancreatitis-associated lung injury in rats.

Wang HH, Tang AM, Chen L, Zhou MT.

Exp Lung Res. 2012 Nov;38(9-10):445-52. doi: 10.3109/01902148.2012.721860. Epub 2012 Sep 24.

PMID:
23005337
14.

Role of neutrophil elastase in lung injury induced by burn-blast combined injury in rats.

Chai JK, Cai JH, Deng HP, Zou XF, Liu W, Hu QG, Shen CA, Yin HN, Zhang XB, Chi YF, Ma L, Feng R.

Burns. 2013 Jun;39(4):745-53. doi: 10.1016/j.burns.2012.08.005. Epub 2012 Sep 19.

PMID:
22999209
15.

Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model.

Murata I, Nozaki R, Ooi K, Ohtake K, Kimura S, Ueda H, Nakano G, Sonoda K, Inoue Y, Uchida H, Kanamoto I, Morimoto Y, Kobayashi J.

J Trauma Acute Care Surg. 2012 Jun;72(6):1548-54. doi: 10.1097/TA.0b013e31824a76b5.

PMID:
22695420
16.

Protective effects of a selective neutrophil elastase inhibitor (sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation.

Inoue Y, Seiyama A, Tanaka H, Ukai I, Akimau P, Nishino M, Shimazu T, Sugimoto H.

Crit Care Med. 2005 Aug;33(8):1814-22.

PMID:
16096460
17.

Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats.

Yang T, Zhang J, Sun L, Zhu X, Li J, Wang J, Chen H, Bao R, Deng X, Hou J, Liu Y.

Inflamm Res. 2012 Jun;61(6):563-9. doi: 10.1007/s00011-012-0445-7. Epub 2012 Apr 7.

PMID:
22484827
18.

Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury.

Sakai S, Tajima H, Miyashita T, Nakanuma S, Makino I, Hayashi H, Nakagawara H, Kitagawa H, Fushida S, Fujimura T, Saito H, Munesue S, Yamamoto Y, Ohta T.

Dig Dis Sci. 2014 Apr;59(4):787-94. doi: 10.1007/s10620-013-2963-8. Epub 2013 Dec 8.

PMID:
24318803
19.

Preventive effect of sivelestat on postoperative respiratory disorders after thoracic esophagectomy.

Nagai Y, Watanabe M, Baba Y, Iwatsuki M, Hirashima K, Karashima R, Kurashige J, Kinoshita K, Baba H.

Surg Today. 2013 Apr;43(4):361-6. doi: 10.1007/s00595-013-0508-6. Epub 2013 Feb 15.

PMID:
23412514
20.

Effects of sivelestat on bronchial inflammatory responses after esophagectomy.

Yamaguchi K, Sugasawa Y, Takeuchi K, Kugimiya T, Kumakura S, Iwanuma Y, Kajiyama Y, Tsurumaru M, Nagaoka I, Inada E.

Int J Mol Med. 2011 Aug;28(2):187-92. doi: 10.3892/ijmm.2011.690. Epub 2011 May 6.

PMID:
21567070
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