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Items: 1 to 20 of 82

1.

Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.

Niola F, Zhao X, Singh D, Sullivan R, Castano A, Verrico A, Zoppoli P, Friedmann-Morvinski D, Sulman E, Barrett L, Zhuang Y, Verma I, Benezra R, Aldape K, Iavarone A, Lasorella A.

J Clin Invest. 2013 Jan;123(1):405-17. doi: 10.1172/JCI63811. Epub 2012 Dec 17. Erratum in: J Clin Invest. 2014 Sep 2;124(9):4134.

2.

Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.

Niibori-Nambu A, Midorikawa U, Mizuguchi S, Hide T, Nagai M, Komohara Y, Nagayama M, Hirayama M, Kobayashi D, Tsubota N, Takezaki T, Makino K, Nakamura H, Takeya M, Kuratsu J, Araki N.

PLoS One. 2013 May 21;8(5):e59558. doi: 10.1371/journal.pone.0059558. Print 2013.

3.

Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.

Soroceanu L, Murase R, Limbad C, Singer E, Allison J, Adrados I, Kawamura R, Pakdel A, Fukuyo Y, Nguyen D, Khan S, Arauz R, Yount GL, Moore DH, Desprez PY, McAllister SD.

Cancer Res. 2013 Mar 1;73(5):1559-69. doi: 10.1158/0008-5472.CAN-12-1943. Epub 2012 Dec 13.

4.

Id proteins synchronize stemness and anchorage to the niche of neural stem cells.

Niola F, Zhao X, Singh D, Castano A, Sullivan R, Lauria M, Nam HS, Zhuang Y, Benezra R, Di Bernardo D, Iavarone A, Lasorella A.

Nat Cell Biol. 2012 Apr 22;14(5):477-87. doi: 10.1038/ncb2490.

5.

Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma.

Barrett LE, Granot Z, Coker C, Iavarone A, Hambardzumyan D, Holland EC, Nam HS, Benezra R.

Cancer Cell. 2012 Jan 17;21(1):11-24. doi: 10.1016/j.ccr.2011.11.025.

6.

TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma.

Anido J, Sáez-Borderías A, Gonzàlez-Juncà A, Rodón L, Folch G, Carmona MA, Prieto-Sánchez RM, Barba I, Martínez-Sáez E, Prudkin L, Cuartas I, Raventós C, Martínez-Ricarte F, Poca MA, García-Dorado D, Lahn MM, Yingling JM, Rodón J, Sahuquillo J, Baselga J, Seoane J.

Cancer Cell. 2010 Dec 14;18(6):655-68. doi: 10.1016/j.ccr.2010.10.023.

7.

Id-1 plays a key role in cell adhesion in neural stem cells through the preservation of RAP1 signaling.

Tan R, Lee YJ, Chen X.

Cell Adh Migr. 2012 Jan-Feb;6(1):1-3. doi: 10.4161/cam.19809. No abstract available.

9.

Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP).

Tsygankova OM, Wang H, Meinkoth JL.

J Biol Chem. 2013 Aug 23;288(34):24636-46. doi: 10.1074/jbc.M113.464594. Epub 2013 Jul 17.

10.

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.

Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8644-9. doi: 10.1073/pnas.1221478110. Epub 2013 May 6.

11.

Crosstalk between glioma-initiating cells and endothelial cells drives tumor progression.

Jeon HM, Kim SH, Jin X, Park JB, Kim SH, Joshi K, Nakano I, Kim H.

Cancer Res. 2014 Aug 15;74(16):4482-92. doi: 10.1158/0008-5472.CAN-13-1597. Epub 2014 Jun 24.

12.

AURKA governs self-renewal capacity in glioma-initiating cells via stabilization/activation of β-catenin/Wnt signaling.

Xia Z, Wei P, Zhang H, Ding Z, Yang L, Huang Z, Zhang N.

Mol Cancer Res. 2013 Sep;11(9):1101-11. doi: 10.1158/1541-7786.MCR-13-0044. Epub 2013 Jun 12.

13.

TGM2 inhibition attenuates ID1 expression in CD44-high glioma-initiating cells.

Fu J, Yang QY, Sai K, Chen FR, Pang JC, Ng HK, Kwan AL, Chen ZP.

Neuro Oncol. 2013 Oct;15(10):1353-65. doi: 10.1093/neuonc/not079. Epub 2013 Jul 21.

14.

Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas.

Bourkoula E, Mangoni D, Ius T, Pucer A, Isola M, Musiello D, Marzinotto S, Toffoletto B, Sorrentino M, Palma A, Caponnetto F, Gregoraci G, Vindigni M, Pizzolitto S, Falconieri G, De Maglio G, Pecile V, Ruaro ME, Gri G, Parisse P, Casalis L, Scoles G, Skrap M, Beltrami CA, Beltrami AP, Cesselli D.

Stem Cells. 2014 May;32(5):1239-53. doi: 10.1002/stem.1605.

15.

Glioma-initiating cells retain their tumorigenicity through integration of the Sox axis and Oct4 protein.

Ikushima H, Todo T, Ino Y, Takahashi M, Saito N, Miyazawa K, Miyazono K.

J Biol Chem. 2011 Dec 2;286(48):41434-41. doi: 10.1074/jbc.M111.300863. Epub 2011 Oct 10.

16.

Id1/Id3 knockdown inhibits metastatic potential of pancreatic cancer.

Shuno Y, Tsuno NH, Okaji Y, Tsuchiya T, Sakurai D, Nishikawa T, Yoshikawa N, Sasaki K, Hongo K, Tsurita G, Sunami E, Kitayama J, Tokunaga K, Takahashi K, Nagawa H.

J Surg Res. 2010 Jun 1;161(1):76-82. doi: 10.1016/j.jss.2008.10.031. Epub 2008 Nov 29.

PMID:
19515385
17.

RLIP76 is overexpressed in human glioblastomas and is required for proliferation, tumorigenesis and suppression of apoptosis.

Wang Q, Wang JY, Zhang XP, Lv ZW, Fu D, Lu YC, Hu GH, Luo C, Chen JX.

Carcinogenesis. 2013 Apr;34(4):916-26. doi: 10.1093/carcin/bgs401. Epub 2012 Dec 30.

18.

Intracerebral adenovirus-mediated p53 tumor suppressor gene therapy for experimental human glioma.

Li H, Alonso-Vanegas M, Colicos MA, Jung SS, Lochmuller H, Sadikot AF, Snipes GJ, Seth P, Karpati G, Nalbantoglu J.

Clin Cancer Res. 1999 Mar;5(3):637-42.

19.
20.

The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network.

Fareh M, Turchi L, Virolle V, Debruyne D, Almairac F, de-la-Forest Divonne S, Paquis P, Preynat-Seauve O, Krause KH, Chneiweiss H, Virolle T.

Cell Death Differ. 2012 Feb;19(2):232-44. doi: 10.1038/cdd.2011.89. Epub 2011 Jul 1.

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