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HIV-1 Vpu protein mediates the transport of potassium in Saccharomyces cerevisiae.

Herrero L, Monroy N, González ME.

Biochemistry. 2013 Jan 8;52(1):171-7. doi: 10.1021/bi3011175. Epub 2012 Dec 20.


Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice.

Sato K, Misawa N, Fukuhara M, Iwami S, An DS, Ito M, Koyanagi Y.

J Virol. 2012 May;86(9):5000-13. doi: 10.1128/JVI.07062-11. Epub 2012 Feb 22.


Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV-1 release.

Hsu K, Han J, Shinlapawittayatorn K, Deschenes I, Marbán E.

Biophys J. 2010 Sep 22;99(6):1718-25. doi: 10.1016/j.bpj.2010.07.027.


The transmembrane domain of BST-2 determines its sensitivity to down-modulation by human immunodeficiency virus type 1 Vpu.

Rong L, Zhang J, Lu J, Pan Q, Lorgeoux RP, Aloysius C, Guo F, Liu SL, Wainberg MA, Liang C.

J Virol. 2009 Aug;83(15):7536-46. doi: 10.1128/JVI.00620-09. Epub 2009 May 27.


Cell type-dependence for Vpu function.

Geraghty RJ, Talbot KJ, Callahan M, Harper W, Panganiban AT.

J Med Primatol. 1994 Feb-May;23(2-3):146-50.


Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.

Hout DR, Gomez ML, Pacyniak E, Gomez LM, Fegley B, Mulcahy ER, Hill MS, Culley N, Pinson DM, Nothnick W, Powers MF, Wong SW, Stephens EB.

Virology. 2006 Jan 20;344(2):541-59. Epub 2005 Sep 30.


Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIV(KU-1bMC33)) results in the synthesis of two envelope precursor proteins, increased numbers of virus particles associated with the cell surface and is pathogenic for pig-tailed macaques.

Hout DR, Gomez ML, Pacyniak E, Mulcahy ER, Gomez LM, Jackson M, Flick M, Fegley B, McCormick C, Wisdom BJ, Culley N, Pinson DM, Powers M, Wong SW, Stephens EB.

Virology. 2004 May 20;323(1):91-107.


Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release.

Ruiz A, Hill MS, Schmitt K, Guatelli J, Stephens EB.

Virology. 2008 Aug 15;378(1):58-68. doi: 10.1016/j.virol.2008.05.022. Epub 2008 Jun 24.


Effects of Vpu expression on Xenopus oocyte membrane conductance.

Coady MJ, Daniel NG, Tiganos E, Allain B, Friborg J, Lapointe JY, Cohen EA.

Virology. 1998 Apr 25;244(1):39-49.


Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells.

Lambelé M, Koppensteiner H, Symeonides M, Roy NH, Chan J, Schindler M, Thali M.

J Virol. 2015 Mar;89(6):3247-55. doi: 10.1128/JVI.03719-14. Epub 2015 Jan 7.


[Establishment of a high-throughput screening assay for interaction inhibitor between BST-2 and Vpu].

Pang XJ, Hu SQ, Zhang Y, Cen S, Jin Q, Guo F.

Bing Du Xue Bao. 2012 Nov;28(6):633-8. Chinese.


Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317.

Bolduan S, Votteler J, Lodermeyer V, Greiner T, Koppensteiner H, Schindler M, Thiel G, Schubert U.

Virology. 2011 Jul 20;416(1-2):75-85. doi: 10.1016/j.virol.2011.04.009. Epub 2011 May 23.


Bacteria-based analysis of HIV-1 Vpu channel activity.

Taube R, Alhadeff R, Assa D, Krugliak M, Arkin IT.

PLoS One. 2014 Oct 1;9(10):e105387. doi: 10.1371/journal.pone.0105387. eCollection 2014.


Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network.

Dubé M, Roy BB, Guiot-Guillain P, Mercier J, Binette J, Leung G, Cohen EA.

J Virol. 2009 May;83(9):4574-90. doi: 10.1128/JVI.01800-08. Epub 2009 Feb 25.


HIV-1 Vpu's lipid raft association is dispensable for counteraction of the particle release restriction imposed by CD317/Tetherin.

Fritz JV, Tibroni N, Keppler OT, Fackler OT.

Virology. 2012 Mar 1;424(1):33-44. doi: 10.1016/j.virol.2011.12.008. Epub 2012 Jan 4.

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