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Results: 1 to 20 of 87

1.

Identification of novel interacting partners of Sirtuin6.

Polyakova O, Borman S, Grimley R, Vamathevan J, Hayes B, Solari R.

PLoS One. 2012;7(12):e51555. doi: 10.1371/journal.pone.0051555. Epub 2012 Dec 11.

PMID:
23240041
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.

Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R.

Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041.

PMID:
20141841
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair.

McCord RA, Michishita E, Hong T, Berber E, Boxer LD, Kusumoto R, Guan S, Shi X, Gozani O, Burlingame AL, Bohr VA, Chua KF.

Aging (Albany NY). 2009 Jan 15;1(1):109-21.

PMID:
20157594
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

Toiber D, Erdel F, Bouazoune K, Silberman DM, Zhong L, Mulligan P, Sebastian C, Cosentino C, Martinez-Pastor B, Giacosa S, D'Urso A, Näär AM, Kingston R, Rippe K, Mostoslavsky R.

Mol Cell. 2013 Aug 22;51(4):454-68. doi: 10.1016/j.molcel.2013.06.018. Epub 2013 Aug 1.

PMID:
23911928
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging.

Jia G, Su L, Singhal S, Liu X.

Mol Cell Biochem. 2012 May;364(1-2):345-50. doi: 10.1007/s11010-012-1236-8. Review.

PMID:
22286818
[PubMed - indexed for MEDLINE]
6.

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.

Grimley R, Polyakova O, Vamathevan J, McKenary J, Hayes B, Patel C, Smith J, Bridges A, Fosberry A, Bhardwaja A, Mouzon B, Chung CW, Barrett N, Richmond N, Modha S, Solari R.

PLoS One. 2012;7(7):e39847. doi: 10.1371/journal.pone.0039847. Epub 2012 Jul 6. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/9c1a5765-6471-401f-bc74-a916c8ead46f.

PMID:
22792191
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

Tsai YC, Greco TM, Boonmee A, Miteva Y, Cristea IM.

Mol Cell Proteomics. 2012 May;11(5):60-76. doi: 10.1074/mcp.A111.015156.

PMID:
22586326
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A proteomic perspective of Sirtuin 6 (SIRT6) phosphorylation and interactions and their dependence on its catalytic activity.

Miteva YV, Cristea IM.

Mol Cell Proteomics. 2014 Jan;13(1):168-83. doi: 10.1074/mcp.M113.032847. Epub 2013 Oct 25.

PMID:
24163442
[PubMed - indexed for MEDLINE]
9.

Functional dissection of SIRT6: identification of domains that regulate histone deacetylase activity and chromatin localization.

Tennen RI, Berber E, Chua KF.

Mech Ageing Dev. 2010 Mar;131(3):185-92. doi: 10.1016/j.mad.2010.01.006. Epub 2010 Feb 1.

PMID:
20117128
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SIRT6 exhibits nucleosome-dependent deacetylase activity.

Gil R, Barth S, Kanfi Y, Cohen HY.

Nucleic Acids Res. 2013 Oct;41(18):8537-45. doi: 10.1093/nar/gkt642. Epub 2013 Jul 26.

PMID:
23892288
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

Tsai YC, Greco TM, Boonmee A, Miteva Y, Cristea IM.

Mol Cell Proteomics. 2012 Feb;11(2):M111.015156. doi: 10.1074/mcp.M111.015156. Epub 2011 Dec 5.

PMID:
22147730
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination.

Ronnebaum SM, Wu Y, McDonough H, Patterson C.

Mol Cell Biol. 2013 Nov;33(22):4461-72. doi: 10.1128/MCB.00480-13. Epub 2013 Sep 16.

PMID:
24043303
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.

Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21790-4. doi: 10.1073/pnas.1016306107. Epub 2010 Nov 22.

PMID:
21098266
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW.

Cell. 2006 Jan 27;124(2):315-29.

PMID:
16439206
[PubMed - indexed for MEDLINE]
Free Article
15.

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.

Law IK, Liu L, Xu A, Lam KS, Vanhoutte PM, Che CM, Leung PT, Wang Y.

Proteomics. 2009 May;9(9):2444-56. doi: 10.1002/pmic.200800738.

PMID:
19343720
[PubMed - indexed for MEDLINE]
16.

Chromatin and beyond: the multitasking roles for SIRT6.

Kugel S, Mostoslavsky R.

Trends Biochem Sci. 2014 Feb;39(2):72-81. doi: 10.1016/j.tibs.2013.12.002. Epub 2014 Jan 14. Review.

PMID:
24438746
[PubMed - indexed for MEDLINE]
17.

Genetic identification of a network of factors that functionally interact with the nucleosome remodeling ATPase ISWI.

Burgio G, La Rocca G, Sala A, Arancio W, Di Gesù D, Collesano M, Sperling AS, Armstrong JA, van Heeringen SJ, Logie C, Tamkun JW, Corona DF.

PLoS Genet. 2008 Jun 6;4(6):e1000089. doi: 10.1371/journal.pgen.1000089.

PMID:
18535655
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

SIRT6: a master epigenetic gatekeeper of glucose metabolism.

Zhong L, Mostoslavsky R.

Transcription. 2010 Jul-Aug;1(1):17-21. doi: 10.4161/trns.1.1.12143.

PMID:
21327158
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

New nuclear partners for nucleosome assembly protein 1: unexpected associations.

Seebart C, Prenni J, Tomschik M, Zlatanova J.

Biochem Cell Biol. 2010 Dec;88(6):927-36. doi: 10.1139/O10-115.

PMID:
21102655
[PubMed - indexed for MEDLINE]
20.

Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks.

Kawahara TL, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY.

PLoS Genet. 2011 Jun;7(6):e1002153. doi: 10.1371/journal.pgen.1002153. Epub 2011 Jun 30.

PMID:
21738489
[PubMed - indexed for MEDLINE]
Free PMC Article

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