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Results: 1 to 20 of 97

1.

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer.

Kreso A, O'Brien CA, van Galen P, Gan OI, Notta F, Brown AM, Ng K, Ma J, Wienholds E, Dunant C, Pollett A, Gallinger S, McPherson J, Mullighan CG, Shibata D, Dick JE.

Science. 2013 Feb 1;339(6119):543-8. doi: 10.1126/science.1227670. Epub 2012 Dec 13.

PMID:
23239622
[PubMed - indexed for MEDLINE]
Free Article
2.

Tumor heterogeneity and response to chemotherapy.

Sugino S, Janicki PK.

Pharmacogenomics. 2013 Dec;14(16):1949. doi: 10.2217/pgs.13.175. No abstract available.

PMID:
24279849
[PubMed - indexed for MEDLINE]
3.

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

Humphries A, Cereser B, Gay LJ, Miller DS, Das B, Gutteridge A, Elia G, Nye E, Jeffery R, Poulsom R, Novelli MR, Rodriguez-Justo M, McDonald SA, Wright NA, Graham TA.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2490-9. doi: 10.1073/pnas.1220353110. Epub 2013 Jun 13.

PMID:
23766371
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Intratumor heterogeneity: finding the needle in a haystack for cancer treatment.

Camps J, Ried T, Castells A.

Gastroenterology. 2013 Jul;145(1):242-4. doi: 10.1053/j.gastro.2013.05.031. Epub 2013 May 29. No abstract available.

PMID:
23726878
[PubMed - indexed for MEDLINE]
5.

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

Notta F, Mullighan CG, Wang JC, Poeppl A, Doulatov S, Phillips LA, Ma J, Minden MD, Downing JR, Dick JE.

Nature. 2011 Jan 20;469(7330):362-7. doi: 10.1038/nature09733. Erratum in: Nature. 2011 Mar 10;471(7337):254.

PMID:
21248843
[PubMed - indexed for MEDLINE]
6.

Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs.

Rao GH, Liu HM, Li BW, Hao JJ, Yang YL, Wang MR, Wang XH, Wang J, Jin HJ, Du L, Chen Q.

Acta Pharmacol Sin. 2013 Jun;34(6):793-804. doi: 10.1038/aps.2013.56.

PMID:
23736004
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.

Siegmund KD, Marjoram P, Woo YJ, Tavaré S, Shibata D.

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4828-33. doi: 10.1073/pnas.0810276106. Epub 2009 Mar 4.

PMID:
19261858
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, Dipersio JF, Wilson RK, Ley TJ.

Cancer Cell. 2014 Mar 17;25(3):379-92. doi: 10.1016/j.ccr.2014.01.031. Epub 2014 Mar 6.

PMID:
24613412
[PubMed - indexed for MEDLINE]
9.

Clonal competition with alternating dominance in multiple myeloma.

Keats JJ, Chesi M, Egan JB, Garbitt VM, Palmer SE, Braggio E, Van Wier S, Blackburn PR, Baker AS, Dispenzieri A, Kumar S, Rajkumar SV, Carpten JD, Barrett M, Fonseca R, Stewart AK, Bergsagel PL.

Blood. 2012 Aug 2;120(5):1067-76. doi: 10.1182/blood-2012-01-405985. Epub 2012 Apr 12.

PMID:
22498740
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors.

Anaka M, Hudson C, Lo PH, Do H, Caballero OL, Davis ID, Dobrovic A, Cebon J, Behren A.

BMC Med Genomics. 2013 Oct 11;6:40. doi: 10.1186/1755-8794-6-40.

PMID:
24119551
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

STAT5a-targeting miRNA enhances chemosensitivity to cisplatin and 5-fluorouracil in human colorectal cancer cells.

Hong X, Chen G, Wang M, Lou C, Mao Y, Li Z, Zhang Y.

Mol Med Rep. 2012 May;5(5):1215-9. doi: 10.3892/mmr.2012.801. Epub 2012 Feb 21.

PMID:
22367509
[PubMed - indexed for MEDLINE]
12.

Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence.

Luetzkendorf J, Mueller LP, Mueller T, Caysa H, Nerger K, Schmoll HJ.

J Cell Mol Med. 2010 Sep;14(9):2292-304. doi: 10.1111/j.1582-4934.2009.00794.x.

PMID:
19508388
[PubMed - indexed for MEDLINE]
13.

Cancer. Cancer cell phenotypes, in fifty shades of grey.

Marusyk A, Polyak K.

Science. 2013 Feb 1;339(6119):528-9. doi: 10.1126/science.1234415. No abstract available.

PMID:
23372002
[PubMed - indexed for MEDLINE]
14.

Epigenetic alteration of PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFα-induced apoptosis.

Lee JH, Kang MJ, Han HY, Lee MG, Jeong SI, Ryu BK, Ha TK, Her NG, Han J, Park SJ, Lee KY, Kim HJ, Chi SG.

Clin Cancer Res. 2011 Dec 15;17(24):7551-62. doi: 10.1158/1078-0432.CCR-11-1026. Epub 2011 Oct 6.

PMID:
21980136
[PubMed - indexed for MEDLINE]
Free Article
15.

Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization.

Sottoriva A, Spiteri I, Shibata D, Curtis C, Tavaré S.

Cancer Res. 2013 Jan 1;73(1):41-9. doi: 10.1158/0008-5472.CAN-12-2273. Epub 2012 Oct 22.

PMID:
23090114
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.

Pang R, Law WL, Chu AC, Poon JT, Lam CS, Chow AK, Ng L, Cheung LW, Lan XR, Lan HY, Tan VP, Yau TC, Poon RT, Wong BC.

Cell Stem Cell. 2010 Jun 4;6(6):603-15. doi: 10.1016/j.stem.2010.04.001.

PMID:
20569697
[PubMed - indexed for MEDLINE]
Free Article
17.

Intratumoral functional heterogeneity and chemotherapy.

Sipos F, Constantinovits M, Műzes G.

World J Gastroenterol. 2014 Mar 14;20(10):2429-32. doi: 10.3748/wjg.v20.i10.2429. Review.

PMID:
24627580
[PubMed - in process]
Free PMC Article
18.

The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information.

Allen WL, Jithesh PV, Oliver GR, Proutski I, Longley DB, Lenz HJ, Proutski V, Harkin P, Johnston PG.

BMC Cancer. 2010 Dec 20;10:687. doi: 10.1186/1471-2407-10-687.

PMID:
21172019
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Evolution of intratumoral genetic heterogeneity during colorectal cancer progression.

Losi L, Baisse B, Bouzourene H, Benhattar J.

Carcinogenesis. 2005 May;26(5):916-22. Epub 2005 Feb 24.

PMID:
15731168
[PubMed - indexed for MEDLINE]
Free Article
20.

The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.

Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M.

Ann Surg Oncol. 2013 Apr;20(4):1395-402. doi: 10.1245/s10434-012-2657-z. Epub 2012 Sep 14.

PMID:
22976378
[PubMed - indexed for MEDLINE]

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