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Items: 1 to 20 of 111

1.

Identification and analysis of murine pancreatic islet enhancers.

Tennant BR, Robertson AG, Kramer M, Li L, Zhang X, Beach M, Thiessen N, Chiu R, Mungall K, Whiting CJ, Sabatini PV, Kim A, Gottardo R, Marra MA, Lynn FC, Jones SJ, Hoodless PA, Hoffman BG.

Diabetologia. 2013 Mar;56(3):542-52. doi: 10.1007/s00125-012-2797-5. Epub 2012 Dec 14.

PMID:
23238790
2.

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.

Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, Dai D, Zhao Y, Hirst M, Verchere CB, Helgason CD, Marra MA, Jones SJ, Hoodless PA.

Genome Res. 2010 Aug;20(8):1037-51. doi: 10.1101/gr.104356.109. Epub 2010 Jun 15.

3.

The study of regulatory effects of Pdx-1, MafA and NeuroD1 on the activity of porcine insulin promoter and the expression of human islet amyloid polypeptide.

Liu XD, Ruan JX, Xia JH, Yang SL, Fan JH, Li K.

Mol Cell Biochem. 2014 Sep;394(1-2):59-66. doi: 10.1007/s11010-014-2081-8. Epub 2014 May 14.

PMID:
24825179
4.

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

J Clin Invest. 2009 Jul;119(7):1888-98. doi: 10.1172/JCI37028.

5.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.

6.

Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population.

Kubo A, Stull R, Takeuchi M, Bonham K, Gouon-Evans V, Sho M, Iwano M, Saito Y, Keller G, Snodgrass R.

PLoS One. 2011;6(9):e24058. doi: 10.1371/journal.pone.0024058. Epub 2011 Sep 13.

7.

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets.

Dai C, Brissova M, Hang Y, Thompson C, Poffenberger G, Shostak A, Chen Z, Stein R, Powers AC.

Diabetologia. 2012 Mar;55(3):707-18. doi: 10.1007/s00125-011-2369-0. Epub 2011 Dec 14.

8.

Programming of human umbilical cord mesenchymal stem cells in vitro to promote pancreatic gene expression.

Wang H, Yang Y, Ho G, Lin X, Wu W, Li W, Lin L, Feng X, Huo X, Jiang J, Liu X, Huang T, Wei C, Ma L.

Mol Med Rep. 2013 Sep;8(3):769-74. doi: 10.3892/mmr.2013.1598. Epub 2013 Jul 23.

PMID:
23900717
9.

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.

Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L.

J Biol Chem. 2009 Nov 6;284(45):31236-48. doi: 10.1074/jbc.M109.048694. Epub 2009 Sep 15.

10.

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G.

Development. 2010 Jan;137(2):203-12. doi: 10.1242/dev.041673.

11.

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells.

Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R.

Mol Cell Biol. 2003 Sep;23(17):6049-62.

12.

Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1.

Sharma S, Jhala US, Johnson T, Ferreri K, Leonard J, Montminy M.

Mol Cell Biol. 1997 May;17(5):2598-604.

13.

The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.

Serup P, Petersen HV, Pedersen EE, Edlund H, Leonard J, Petersen JS, Larsson LI, Madsen OD.

Biochem J. 1995 Sep 15;310 ( Pt 3):997-1003.

14.

The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.

Pound LD, Hang Y, Sarkar SA, Wang Y, Milam LA, Oeser JK, Printz RL, Lee CE, Stein R, Hutton JC, O'Brien RM.

Biochem J. 2011 Jan 1;433(1):95-105. doi: 10.1042/BJ20101488.

15.

Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells.

Wilson LM, Wong SH, Yu N, Geras-Raaka E, Raaka BM, Gershengorn MC.

Stem Cells. 2009 Nov;27(11):2703-11. doi: 10.1002/stem.229.

16.

Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.

Martin CC, Flemming BP, Wang Y, Oeser JK, O'Brien RM.

J Mol Endocrinol. 2008 Nov;41(5):315-28. doi: 10.1677/JME-08-0062. Epub 2008 Aug 27.

17.

Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas.

Van Velkinburgh JC, Samaras SE, Gerrish K, Artner I, Stein R.

J Biol Chem. 2005 Nov 18;280(46):38438-44. Epub 2005 Sep 7.

18.

Pdx1 and USF transcription factors co-ordinately regulate Alx3 gene expression in pancreatic β-cells.

Fernández-Pérez A, Vallejo M.

Biochem J. 2014 Oct 15;463(2):287-96. doi: 10.1042/BJ20140643.

PMID:
25040025
19.

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R.

Mol Cell Biol. 2006 Aug;26(15):5735-43.

20.

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages.

Limbert C, Päth G, Ebert R, Rothhammer V, Kassem M, Jakob F, Seufert J.

Cytotherapy. 2011 Aug;13(7):802-13. doi: 10.3109/14653249.2011.571248. Epub 2011 Apr 21.

PMID:
21506889
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