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Adiponectin corrects high-fat diet-induced disturbances in muscle metabolomic profile and whole-body glucose homeostasis.

Liu Y, Turdi S, Park T, Morris NJ, Deshaies Y, Xu A, Sweeney G.

Diabetes. 2013 Mar;62(3):743-52. doi: 10.2337/db12-0687. Epub 2012 Dec 13.


High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance.

Hoeks J, Wilde Jd, Hulshof MF, Berg SA, Schaart G, Dijk KW, Smit E, Mariman EC.

PLoS One. 2011;6(11):e27274. doi: 10.1371/journal.pone.0027274. Epub 2011 Nov 28.


Enhanced lipid oxidation and maintenance of muscle insulin sensitivity despite glucose intolerance in a diet-induced obesity mouse model.

Trajcevski KE, O'Neill HM, Wang DC, Thomas MM, Al-Sajee D, Steinberg GR, Ceddia RB, Hawke TJ.

PLoS One. 2013 Aug 12;8(8):e71747. doi: 10.1371/journal.pone.0071747. eCollection 2013.


Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice.

Liu Y, Palanivel R, Rai E, Park M, Gabor TV, Scheid MP, Xu A, Sweeney G.

Diabetes. 2015 Jan;64(1):36-48. doi: 10.2337/db14-0267. Epub 2014 Jul 28.


Chronic inflammation exacerbates glucose metabolism disorders in C57BL/6J mice fed with high-fat diet.

Wu Y, Wu T, Wu J, Zhao L, Li Q, Varghese Z, Moorhead JF, Powis SH, Chen Y, Ruan XZ.

J Endocrinol. 2013 Oct 28;219(3):195-204. doi: 10.1530/JOE-13-0160. Print 2013 Dec.


Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice.

Cao K, Xu J, Zou X, Li Y, Chen C, Zheng A, Li H, Li H, Szeto IM, Shi Y, Long J, Liu J, Feng Z.

Free Radic Biol Med. 2014 Feb;67:396-407. doi: 10.1016/j.freeradbiomed.2013.11.029. Epub 2013 Dec 6.


Sex differences in the effect of high-fat diet feeding on rat white adipose tissue mitochondrial function and insulin sensitivity.

Amengual-Cladera E, Lladó I, Gianotti M, Proenza AM.

Metabolism. 2012 Aug;61(8):1108-17. doi: 10.1016/j.metabol.2011.12.016. Epub 2012 Mar 7.


High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression.

White AT, Philp A, Fridolfsson HN, Schilling JM, Murphy AN, Hamilton DL, McCurdy CE, Patel HH, Schenk S.

Am J Physiol Endocrinol Metab. 2014 Nov 1;307(9):E764-72. doi: 10.1152/ajpendo.00001.2014. Epub 2014 Aug 26.


Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.


Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance.

Wang XA, Zhang R, Zhang S, Deng S, Jiang D, Zhong J, Yang L, Wang T, Hong S, Guo S, She ZG, Zhang XD, Li H.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E485-95. doi: 10.1152/ajpendo.00505.2012. Epub 2013 May 21.


Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding.

Montgomery MK, Hallahan NL, Brown SH, Liu M, Mitchell TW, Cooney GJ, Turner N.

Diabetologia. 2013 May;56(5):1129-39. doi: 10.1007/s00125-013-2846-8. Epub 2013 Feb 20.


The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice.

Ceddia RP, Lee D, Maulis MF, Carboneau BA, Threadgill DW, Poffenberger G, Milne G, Boyd KL, Powers AC, McGuinness OP, Gannon M, Breyer RM.

Endocrinology. 2016 Jan;157(1):220-32. doi: 10.1210/en.2015-1693. Epub 2015 Oct 20.


Metabolomic profiling in liver of adiponectin-knockout mice uncovers lysophospholipid metabolism as an important target of adiponectin action.

Liu Y, Sen S, Wannaiampikul S, Palanivel R, Hoo RL, Isserlin R, Bader GD, Tungtrongchitr R, Deshaies Y, Xu A, Sweeney G.

Biochem J. 2015 Jul 1;469(1):71-82. doi: 10.1042/BJ20141455. Epub 2015 Apr 27.


Adiponectin is expressed in the pancreas of high-fat-diet-fed mice and protects pancreatic endothelial function during the development of type 2 diabetes.

Liu XX, Liu KY, Li P, Han S, Peng XD, Shen L.

Diabetes Metab. 2014 Nov;40(5):363-72. doi: 10.1016/j.diabet.2014.05.004. Epub 2014 Jun 27.


Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations.

Liu Z, Lim CY, Su MY, Soh SL, Shui G, Wenk MR, Grove KL, Radda GK, Han W, Xiao X.

J Endocrinol. 2013 Oct 4;219(2):131-43. doi: 10.1530/JOE-13-0111. Print 2013 Nov.


Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.

Pal M, Wunderlich CM, Spohn G, Brönneke HS, Schmidt-Supprian M, Wunderlich FT.

PLoS One. 2013;8(1):e54247. doi: 10.1371/journal.pone.0054247. Epub 2013 Jan 17.


Delivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasis.

Vu V, Liu Y, Sen S, Xu A, Sweeney G.

Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E168-75. doi: 10.1152/ajpendo.00493.2012. Epub 2012 Nov 6.


Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle.

Franko A, von Kleist-Retzow JC, Böse M, Sanchez-Lasheras C, Brodesser S, Krut O, Kunz WS, Wiedermann D, Hoehn M, Stöhr O, Moll L, Freude S, Krone W, Schubert M, Wiesner RJ.

J Mol Med (Berl). 2012 Oct;90(10):1145-60. doi: 10.1007/s00109-012-0887-y. Epub 2012 Mar 13.


Activity-based protein profiling reveals mitochondrial oxidative enzyme impairment and restoration in diet-induced obese mice.

Sadler NC, Angel TE, Lewis MP, Pederson LM, Chauvigné-Hines LM, Wiedner SD, Zink EM, Smith RD, Wright AT.

PLoS One. 2012;7(10):e47996. doi: 10.1371/journal.pone.0047996. Epub 2012 Oct 24.

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