Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 83

1.

Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.

Huebner AJ, Dai D, Morasso M, Schmidt EE, Schäfer M, Werner S, Roop DR.

Dev Cell. 2012 Dec 11;23(6):1238-46. doi: 10.1016/j.devcel.2012.11.002.

PMID:
23237955
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus.

Chen H, Li J, Li H, Hu Y, Tevebaugh W, Yamamoto M, Que J, Chen X.

PLoS One. 2012;7(5):e36504. doi: 10.1371/journal.pone.0036504. Epub 2012 May 2. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/b2554ac2-5eec-4fc1-b625-c79f0cc064ed.

PMID:
22567161
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic analysis of cytoprotective functions supported by graded expression of Keap1.

Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.

Mol Cell Biol. 2010 Jun;30(12):3016-26. doi: 10.1128/MCB.01591-09. Epub 2010 Apr 19.

PMID:
20404090
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.

He X, Ma Q.

J Pharmacol Exp Ther. 2010 Jan;332(1):66-75. doi: 10.1124/jpet.109.160465. Epub 2009 Oct 6.

PMID:
19808700
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice.

Yagishita Y, Fukutomi T, Sugawara A, Kawamura H, Takahashi T, Pi J, Uruno A, Yamamoto M.

Diabetes. 2014 Feb;63(2):605-18. doi: 10.2337/db13-0909. Epub 2013 Nov 1.

PMID:
24186865
[PubMed - indexed for MEDLINE]
Free Article
6.

The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.

Copple IM, Goldring CE, Jenkins RE, Chia AJ, Randle LE, Hayes JD, Kitteringham NR, Park BK.

Hepatology. 2008 Oct;48(4):1292-301. doi: 10.1002/hep.22472.

PMID:
18785192
[PubMed - indexed for MEDLINE]
7.

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.

Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.

Nat Cell Biol. 2010 Mar;12(3):213-23. doi: 10.1038/ncb2021. Epub 2010 Feb 21.

PMID:
20173742
[PubMed - indexed for MEDLINE]
8.

KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.

Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD.

Mol Cell Biol. 2011 May;31(9):1800-11. doi: 10.1128/MCB.05036-11. Epub 2011 Mar 7.

PMID:
21383067
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein.

Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC, Roop DR.

J Cell Biol. 2000 Oct 16;151(2):389-400.

PMID:
11038185
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The Keap1-Nrf2 system as an in vivo sensor for electrophiles.

Uruno A, Motohashi H.

Nitric Oxide. 2011 Aug 1;25(2):153-60. doi: 10.1016/j.niox.2011.02.007. Epub 2011 Mar 6.

PMID:
21385624
[PubMed - indexed for MEDLINE]
11.

Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium.

Chen H, Hu Y, Fang Y, Djukic Z, Yamamoto M, Shaheen NJ, Orlando RC, Chen X.

Gut. 2014 May;63(5):711-9. doi: 10.1136/gutjnl-2012-303731. Epub 2013 May 15.

PMID:
23676441
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of notch1 signaling by nrf2: implications for tissue regeneration.

Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, Kensler TW.

Sci Signal. 2010 Jul 13;3(130):ra52. doi: 10.1126/scisignal.2000762.

PMID:
20628156
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

He X, Chen MG, Lin GX, Ma Q.

J Biol Chem. 2006 Aug 18;281(33):23620-31. Epub 2006 Jun 19.

PMID:
16785233
[PubMed - indexed for MEDLINE]
Free Article
14.

Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis.

Yoneda K, Nakagawa T, Lawrence OT, Huard J, Demitsu T, Kubota Y, Presland RB.

J Invest Dermatol. 2012 Apr;132(4):1206-14. doi: 10.1038/jid.2011.460. Epub 2012 Jan 26.

PMID:
22277945
[PubMed - indexed for MEDLINE]
Free Article
15.

The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling.

Kanzaki H, Shinohara F, Kajiya M, Kodama T.

J Biol Chem. 2013 Aug 9;288(32):23009-20. doi: 10.1074/jbc.M113.478545. Epub 2013 Jun 25. Erratum in: J Biol Chem. 2014 Feb 28;289(9):5536.

PMID:
23801334
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.

Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S, Li RC, Xu Y, Dore S, Cao W.

Free Radic Biol Med. 2012 Mar 1;52(5):928-36. doi: 10.1016/j.freeradbiomed.2011.12.006. Epub 2011 Dec 17.

PMID:
22226832
[PubMed - indexed for MEDLINE]
17.

Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis.

Ohkoshi A, Suzuki T, Ono M, Kobayashi T, Yamamoto M.

Cancer Prev Res (Phila). 2013 Feb;6(2):149-59. doi: 10.1158/1940-6207.CAPR-12-0401-T. Epub 2012 Dec 18.

PMID:
23250896
[PubMed - indexed for MEDLINE]
18.

Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice.

Randle LE, Goldring CE, Benson CA, Metcalfe PN, Kitteringham NR, Park BK, Williams DP.

Toxicology. 2008 Jan 20;243(3):249-60. Epub 2007 Oct 23.

PMID:
18078705
[PubMed - indexed for MEDLINE]
19.

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.

J Biol Chem. 2003 Mar 7;278(10):8135-45. Epub 2002 Dec 27.

PMID:
12506115
[PubMed - indexed for MEDLINE]
Free Article
20.

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.

Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, Kumagai Y.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):645-50. Epub 2007 Sep 18.

PMID:
17904103
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk