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Results: 1 to 20 of 105

1.

Enhanced phase II detoxification contributes to beneficial effects of dietary restriction as revealed by multi-platform metabolomics studies.

Wen H, Yang HJ, An YJ, Kim JM, Lee DH, Jin X, Park SW, Min KJ, Park S.

Mol Cell Proteomics. 2013 Mar;12(3):575-86. doi: 10.1074/mcp.M112.021352. Epub 2012 Dec 9.

PMID:
23230277
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics.

Kumar BS, Chung BC, Kwon OS, Jung BH.

J Appl Toxicol. 2012 Jul;32(7):505-20. doi: 10.1002/jat.1746. Epub 2011 Dec 1.

PMID:
22131085
[PubMed - indexed for MEDLINE]
3.

Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride.

Khemawoot P, Maruyama C, Tsukada H, Noda H, Ishizaki J, Yokogawa K, Miyamoto K.

Biopharm Drug Dispos. 2007 Sep;28(6):331-8.

PMID:
17617793
[PubMed - indexed for MEDLINE]
4.

Evaluating effects of penicillin treatment on the metabolome of rats.

Sun J, Schnackenberg LK, Khare S, Yang X, Greenhaw J, Salminen W, Mendrick DL, Beger RD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 1;932:134-43. doi: 10.1016/j.jchromb.2013.05.030. Epub 2013 Jun 7.

PMID:
23831706
[PubMed - indexed for MEDLINE]
5.

Targeting metabolomics analysis of the sunscreen agent 2-ethylhexyl 4-(N,N-dimethylamino)benzoate in human urine by automated on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry with liquid chromatography-time-of-flight/mass spectrometry confirmation.

León-González Z, Ferreiro-Vera C, Priego-Capote F, de Castro MD.

J Chromatogr A. 2011 May 20;1218(20):3013-21. doi: 10.1016/j.chroma.2011.03.045. Epub 2011 Mar 26.

PMID:
21481400
[PubMed - indexed for MEDLINE]
6.

Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis.

Moazzami AA, Andersson R, Kamal-Eldin A.

NMR Biomed. 2011 Jun;24(5):499-505. doi: 10.1002/nbm.1615. Epub 2010 Nov 30.

PMID:
21674651
[PubMed - indexed for MEDLINE]
7.

Chronic caloric restriction partially protects against age-related alteration in serum metabolome.

De Guzman JM, Ku G, Fahey R, Youm YH, Kass I, Ingram DK, Dixit VD, Kheterpal I.

Age (Dordr). 2013 Aug;35(4):1091-104. doi: 10.1007/s11357-012-9430-x. Epub 2012 Jun 4.

PMID:
22661299
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Metabonomic study of genkwa flos-induced hepatotoxicity and effect of herb-processing procedure on toxicity.

Geng L, Ma C, Zhang L, Yang G, Cui Y, Su D, Zhao X, Liu Z, Bi K, Chen X.

Phytother Res. 2013 Apr;27(4):521-9. doi: 10.1002/ptr.4748. Epub 2012 May 31.

PMID:
22648611
[PubMed - indexed for MEDLINE]
9.

Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat.

Xie Z, Li H, Wang K, Lin J, Wang Q, Zhao G, Jia W, Zhang Q.

Metabolism. 2010 Apr;59(4):554-60. doi: 10.1016/j.metabol.2009.08.022. Epub 2009 Nov 14.

PMID:
19913842
[PubMed - indexed for MEDLINE]
10.

A combination of metabolomics and metallomics studies of urine and serum from hypercholesterolaemic rats after berberine injection.

Liu F, Gan PP, Wu H, Woo WS, Ong ES, Li SF.

Anal Bioanal Chem. 2012 May;403(3):847-56. doi: 10.1007/s00216-012-5923-9. Epub 2012 Mar 21.

PMID:
22434276
[PubMed - indexed for MEDLINE]
11.

Liquiritigenin, a flavonoid aglycone from licorice, has a choleretic effect and the ability to induce hepatic transporters and phase-II enzymes.

Kim YW, Kang HE, Lee MG, Hwang SJ, Kim SC, Lee CH, Kim SG.

Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G372-81. doi: 10.1152/ajpgi.90524.2008. Epub 2008 Dec 12.

PMID:
19074639
[PubMed - indexed for MEDLINE]
Free Article
12.

Metabolic signatures of esophageal cancer: NMR-based metabolomics and UHPLC-based focused metabolomics of blood serum.

Zhang X, Xu L, Shen J, Cao B, Cheng T, Zhao T, Liu X, Zhang H.

Biochim Biophys Acta. 2013 Aug;1832(8):1207-16. doi: 10.1016/j.bbadis.2013.03.009. Epub 2013 Mar 20.

PMID:
23524237
[PubMed - indexed for MEDLINE]
Free Article
13.

Analysis of urinary metabolic profile in aging rats undergoing caloric restriction.

Zhang Y, Yan S, Gao X, Xiong X, Dai W, Liu X, Li L, Zhang W, Mei C.

Aging Clin Exp Res. 2012 Feb;24(1):79-84. doi: 10.3275/7519. Epub 2011 Feb 21.

PMID:
21339700
[PubMed - indexed for MEDLINE]
14.

Metabolomic investigations of American oysters using H-NMR spectroscopy.

Tikunov AP, Johnson CB, Lee H, Stoskopf MK, Macdonald JM.

Mar Drugs. 2010 Oct 8;8(10):2578-96. doi: 10.3390/md8102578.

PMID:
21116407
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The impact of blood on liver metabolite profiling - a combined metabolomic and proteomic approach.

Ly-Verdú S, Schaefer A, Kahle M, Groeger T, Neschen S, Arteaga-Salas JM, Ueffing M, de Angelis MH, Zimmermann R.

Biomed Chromatogr. 2014 Feb;28(2):231-40. doi: 10.1002/bmc.3010. Epub 2013 Aug 12.

PMID:
23934789
[PubMed - indexed for MEDLINE]
16.

Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease.

Dumas ME, Kinross J, Nicholson JK.

Gastroenterology. 2014 Jan;146(1):46-62. doi: 10.1053/j.gastro.2013.11.001. Epub 2013 Nov 7.

PMID:
24211299
[PubMed - indexed for MEDLINE]
17.

Metabolomics, pathway regulation, and pathway discovery.

Zhang GF, Sadhukhan S, Tochtrop GP, Brunengraber H.

J Biol Chem. 2011 Jul 8;286(27):23631-5. doi: 10.1074/jbc.R110.171405. Epub 2011 May 12. Review.

PMID:
21566142
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.

Seo KA, Bae SK, Choi YK, Choi CS, Liu KH, Shin JG.

Drug Metab Dispos. 2010 Nov;38(11):2007-13. doi: 10.1124/dmd.110.035295. Epub 2010 Aug 16.

PMID:
20713656
[PubMed - indexed for MEDLINE]
Free Article
19.

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy.

Dunn WB, Broadhurst DI, Atherton HJ, Goodacre R, Griffin JL.

Chem Soc Rev. 2011 Jan;40(1):387-426. doi: 10.1039/b906712b. Epub 2010 Aug 17. Review.

PMID:
20717559
[PubMed - indexed for MEDLINE]
20.

Ultraperformance liquid chromatography-mass spectrometry based comprehensive metabolomics combined with pattern recognition and network analysis methods for characterization of metabolites and metabolic pathways from biological data sets.

Zhang AH, Sun H, Han Y, Yan GL, Yuan Y, Song GC, Yuan XX, Xie N, Wang XJ.

Anal Chem. 2013 Aug 6;85(15):7606-12. doi: 10.1021/ac401793d. Epub 2013 Jul 25.

PMID:
23845028
[PubMed - indexed for MEDLINE]

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